The Venetian Money Market

The long awaited conclusion to the magisterial Money and Banking in Medieval and Renaissance Venice.Originally published in 1997. In 1985 Frederic C. Lane and Reinhold C. Mueller published the magisterial Money and Banking in Medieval and Renaissance Venice, volume 1: Coins and Moneys of Account. Now, after ten years of further research and writing, Reinhold Mueller completes the work that he and the late Frederic Lane began. The history of money and banking in Venice is crucial to an understanding of European economic history. Because of its strategic location between East and West, Venice rapidly rose to a position of preeminence in Mediterranean trade. To keep trade moving from London to Constantinople and beyond, Venetian merchants and bankers created specialized financial institutions to serve private entrepreneurs and public administrators: deposit banks, foreign exchange banks, a grain office, and a bureau of the public debt. This new book clarifies Venice's pivotal role in Italian and international banking and finance. It also sets banking—and panics—in the context of more generalized and recurrent crises involving territorial wars, competition for markets, and debates over interest rates and the question of usury

Ebrei nella Terraferma veneta del Quattrocento

This book is a collection of the proceedings of the study seminar held in Verona on 14 November 2003. This was the occasion for the presentation of the results of archive research performed by young researchers on the Jewish presence in numerous cities and smaller towns of the Venetian hinterland in the fifteenth century (Vicenza, Verona, Treviso, Feltre, and the minor centres of the Polesine and Verona and Vicenza territory). The various themes that are developed though attentive and documented analysis include: the autonomous initiative of the civic communities in the relation with the Jewish moneylenders and the attitude of Venice, divided between protection and the anti-Jewish tensions that were widespread among the lagoon nobility; the encounter and dialectic between the Ashkenazi and Italian components in the communities settled within the cities and hamlets of Veneto; the difference of the social and cultural climate between the first and second half of the fifteenth century, marked by incisive Franciscan preaching and attempts at expulsion from the cities; a look 'from the inside' which opens up the role of women in the economic life of the Jewish communities. Over twenty years after the convention on 'The Jews and Venice' promoted by the Fondazione Cini, these contributions illustrate the revival of study and the ever-present need for comparison and exchange on the issue of the Jewish presence in Italy

The Midpoint Rule as a Variational--Symplectic Integrator. I. Hamiltonian Systems

Numerical algorithms based on variational and symplectic integrators exhibit special features that make them promising candidates for application to general relativity and other constrained Hamiltonian systems. This paper lays part of the foundation for such applications. The midpoint rule for Hamilton's equations is examined from the perspectives of variational and symplectic integrators. It is shown that the midpoint rule preserves the symplectic form, conserves Noether charges, and exhibits excellent long--term energy behavior. The energy behavior is explained by the result, shown here, that the midpoint rule exactly conserves a phase space function that is close to the Hamiltonian. The presentation includes several examples.Comment: 11 pages, 8 figures, REVTe

Healthcare Utilization and Costs in Sepsis Survivors in Germany-Secondary Analysis of a Prospective Cohort Study

Background: Survivors of sepsis often face long-term sequelae after intensive care treatment. Compared to the period of hospitalization, little is known about the ambulatory healthcare utilization in sepsis patients. The study evaluated healthcare utilization and associated costs of sepsis care including allied health professions after initial hospitalization. Methods: Secondary analysis was performed on data in 210 sepsis patients prospectively enrolled from nine intensive care study centers across Germany. Data was collected via structured surveys among their Primary care (Family-) physicians (PCPs) within the first month after discharge from ICU (baseline) and again at 6, 12 and 24 months after discharge, each relating to the period following the last survey. Costs were assessed by standardized cost unit rates from a health care system’s perspective. Changes in healthcare utilization and costs over time were calculated using the Wilcoxon rank-sum test. Results: Of the 210 patients enrolled, 146 (69.5%) patients completed the 24 months follow-up. In total, 109 patients were hospitalized within the first 6 months post-intensive care. Mean total direct costs per patient at 0–6 months were €17,531 (median: €6047), at 7–12 months €9029 (median: €3312), and at 13–24 months €18,703 (median: €12,828). The largest contributor to the total direct costs within the first 6 months was re-hospitalizations (€13,787 (median: €2965). After this first half year, we observed a significant decline in inpatient care costs for re-hospitalizations (p ≤ 0.001). PCPs were visited by more than 95% of patients over 24 months. Conclusions: Sepsis survivors have high health care utilization. Hospital readmissions are frequent and costly. Highest costs and hospitalizations were observed in more than half of patients within the first six months post-intensive care. Among all outpatient care providers, PCPs were consulted most frequently. Clinical impact: Sepsis survivors have a high healthcare utilization and related costs which persist after discharge from hospital. Within outpatient care, possible needs of sepsis survivors as physiotherapy or psychotherapy seem not to be met appropriately. Development of sepsis aftercare programs for early detection and treatment of complications should be prioritized

The roles of inflammation and immune mechanisms in Alzheimer's disease

AbstractThe Alzheimer's Association's Research roundtable met in April 2015 to explore the role of neuroinflammatory mechanisms in the progression of Alzheimer's disease (AD). The ability of innate immune cells, particularly microglia and astrocytes, to mediate neuroinflammation in AD has been implicated as a significant contributor to disease pathogenesis. Adaptive immunity, which plays an important role in responding to injury and some diseases of the central nervous system, may contribute to neuroinflammation in AD as well. Communication between the central and peripheral immune systems may also be important in AD. An increased understanding of the physiology of the innate immune system may aid the identification of new therapeutic targets or mechanisms. The development of predictive animal models and translatable neuroinflammation biomarkers for AD would also facilitate the advancement of novel treatments for innate immunity. Important challenges impeding the advancement of new therapeutic agents and strategies to overcome them were discussed

Determination of the pion charge form factor for Q^2=0.60-1.60 GeV^2

The data analysis for the reaction H(e,e' pi^+)n, which was used to determine values for the charged pion form factor Fpi for values of Q^2=0.6-1.6 GeV^2, has been repeated with careful inspection of all steps and special attention to systematic uncertainties. Also the method used to extract Fpi from the measured longitudinal cross section was critically reconsidered. Final values for the separated longitudinal and transverse cross sections and the extracted values of Fpi are presented.Comment: 11 pages, 6 figure

Charged pion form factor between Q^2=0.60 and 2.45 GeV^2. II. Determination of, and results for, the pion form factor

The charged pion form factor, Fpi(Q^2), is an important quantity which can be used to advance our knowledge of hadronic structure. However, the extraction of Fpi from data requires a model of the 1H(e,e'pi+)n reaction, and thus is inherently model dependent. Therefore, a detailed description of the extraction of the charged pion form factor from electroproduction data obtained recently at Jefferson Lab is presented, with particular focus given to the dominant uncertainties in this procedure. Results for Fpi are presented for Q^2=0.60-2.45 GeV^2. Above Q^2=1.5 GeV^2, the Fpi values are systematically below the monopole parameterization that describes the low Q^2 data used to determine the pion charge radius. The pion form factor can be calculated in a wide variety of theoretical approaches, and the experimental results are compared to a number of calculations. This comparison is helpful in understanding the role of soft versus hard contributions to hadronic structure in the intermediate Q^2 regime.Comment: 18 pages, 11 figure