Issues and challenges: cloud computing e-Government in developing countries

Cloud computing has become essential for IT resources that can be delivered as a service over the Internet. Many e-government services that are used worldwide provide communities with relatively complex applications and services. Governments are still facing many challenges in their implementation of e-government services in general, including Saudi Arabia, such as poor IT infrastructure, lack of finance, and insufficient data security. This research paper investigates the challenges of e-government cloud service models in developing countries. This paper finds that governments in developing countries are influenced by how the top management deals with the attention to the adoption of cloud computing. Further, organisational readiness levels of technologies, such as IT infrastructure, internet availability and social trust of the adoption of new technology as cloud computing, still present limitations for e-government cloud services adoption. Based on the findings of the critical review, this paper identifies the issues and challenges affecting the adoption of cloud computing in e- government such as IT infrastructure, internet availability, and trust adopted new technologies thereby highlighting benefits of cloud computing-based e-government services. Furthermore, we propose recommendations for developing IT systems focused on trust when adopting cloud computing in e-government services (CCEGov)

IoT-HASS: A Framework For Protecting Smart Home Environment

While many solutions have been proposed for smart home security, the problem that no single solution fully protects the smart home environment still exists. In this research we propose a security framework to protect the smart home environment. The proposed framework includes three engines that complement each other to protect the smart home IoT devices. The first engine is an IDS/IPS module that monitors all traffic in the home network and then detects, alerts users, and/or blocks packets using anomaly-based detection. The second engine works as a device management module that scans and verifies IoT devices in the home network, allowing the user to flag any suspect device. The third engine works as a privacy monitoring module that monitors and detects information transmitted in plaintext and alerts the user if such information is detected. We call the proposed system IoT-Home Advanced Security System or IoT-HASS for short. IoT-HASS was developed using Python 3 and can be implemented in two modes of operation. The in-line mode allows the IoT-HASS to be installed in-line with the traffic inside a Raspberry Pi or a Router. In the in-line mode IoT-HASS acts as an IPS that can detect and block threats as well as alert the user. The second mode is the passive mode where IoT-HASS in not installed in-line with the traffic and can act as an IDS that passively monitors the traffic, detecting threats and alerting the user, but not blocking the attack. IoT-HASS was evaluated via four testing scenarios. It demonstrated superior performance in all testing scenarios in detecting attacks such as DDoS attacks, Brute Force Attacks, and Cross Site Scripting (XSS) Attacks. In each of the four test scenarios, we also tested the device management functionality, which we found to successfully scan and display IoT devices for the homeowner. The extensive evaluating and testing of IoT-HASS showed that IoT-HASS can successfully run in a small device such as a Raspberry Pi, and thus, it will most likely run in an embedded device as an IoT device. Our future research will concentrate on strengthening the current features of IoT-HASS to include additional functionalities

Epidemiology of viral hepatitis in Sudan

Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the virus varied from 47%–78%, with a hepatitis B surface antigen prevalence ranging from 6.8% in central Sudan to 26% in southern Sudan. Studies pointed to infection in early childhood in southern Sudan while there was a trend of increasing infection rate with increasing age in northern Sudan. Hepatitis B virus was the commonest cause of chronic liver disease and hepatocellular carcinoma and was the second commonest cause of acute liver failure in the Sudan. Studies of hepatitis C virus showed a low seroprevalence of 2.2%–4.8% and there was no association with schistosomiasis or with parenteral antischistosomal therapy. Hepatitis E virus was the commonest cause of acute hepatitis among pediatric, adult, and displaced populations. Recent introduction of screening of blood and blood products for hepatitis B virus and hepatitis C virus infections and the introduction of hepatitis B virus vaccine as part of the extended program of immunization is expected to reduce the infection rate of these viruses in the Sudan

Cloud computing in government organizations: towards a new comprehensive model

Cloud computing is a new information technology paradigm, one which has been adopted in many different sectors. Many developing countries are working on improving e-government to provide services to their citizens that are integrated and effective. Therefore, the Saudi government has made improving e-government a high priority. The aim of this study is to explore significant factors affecting the adoption of cloud computing in e-government services in Saudi Arabia as a case study. After identifying these factors, we propose a new comprehensive model for the Adoption of Cloud Computing in Saudi G-GOVernment (ACCE-GOV) that has been adopted from the Technology Organisation Environment (TOE) framework and the Diffusion of Innovations (DOI) theory. This research model examines factors of technological context (compatibility, complexity, service quality, security, and relative advantages), organisational context (top management support, organisation size, and technology readiness), environmental context (regulations and competitive pressures), and social context (awareness, trust, and attitude) in regard to the adoption of cloud computing. Ultimately, this study enhances the decision-making of the Saudi government through understanding and highlighting the most important factors that influence the adoption of cloud computing in an e-government context. This is a position paper, reporting on the work in progress. The findings of this study will be useful for the researchers who considers suitability of different methodological approaches for cloud computing adoption and evaluation

Interchangeability and Comparative Effectiveness between Micronized and Non-micronized Products of Glibenclamide Tablets

Background: During the last few years there was wide debate about the interchangeability and effectiveness between circulated products containing Glibenclamide in the market.Objectives: This study aimed to compare the effectiveness of this product “non-micronized” to the originator’s product of Glibenclamide tablets “of micronized” sulfonylurea.Methods: 12 volunteers received a dose of 5mg of Glibenclamide (from test and standard products) under fasting conditions in two separate sessions using randomized crossover design. Blood glucose level for the volunteers was monitored to avoid the development of hypoglycemia. Plasma samples were collected over 24 hours and analyzed using HPLC.Results: The maximum concentration Cmax for the test and reference products were 2.508 ± 0.104 and 3.526 ± 0.118 (ìg/ml) respectively and the area under the curve AUC0-[ were 3.511 ± 0.153 4.572 ± 0.202 (ìg.h/ml) for these products respectively, with a difference of about 24% between the test and reference products in its AUC.Conclusions: The results indicate that the test product is not bioequivalent to reference product. The difference in formulation between micronized product and non-micronized product of Glibenclamide tablets has impact on clinical outcomes.Key words:sulfonylurea,Blood glucose,hypoglycemia

Immunological stimulation for the treatment of leishmaniasis: A modality worthy of serious consideration

Instead of relying on drugs to reduce the parasite burden of leishmaniasis, and waiting for the effector immune response to develop in time to control the parasites, immunotherapy in conjunction with chemotherapy can rapidly induce the effector immune response. With a safe and potent drug plus an affordable therapeutic vaccine (immunostimulant), which remains to be developed, a single visit by patients with visceral or cutaneous leishmaniasis might be sufficient to induce a quick and lasting recovery. Drug toxicity and the emergence of resistance could also be dramatically reduced compared with present long-term monotherapy. Immunotherapy could be an effective addition to chemotherapy for leishmaniasi

Reproductive traits and lactation performance of Kenana cows at Umbenein Livestock Research Station, Sinnar State, Sudan

Sudanese Kenana breed is one of the largest east African Zebu cattle. Its performance is close to the best dairy breeds in Africa. This study aimed to estimate selected reproduction and lactation traits and effects of sire, lactation number and year of calving on those traits in Kenana cows at Umbenein Livestock Research Station, Sinnar State, Sudan. The official records of the station during the years 2000 -2017 were used. Overall mean of age at first calving, calving interval, open, dry and lactation periods (day) and lactation, daily and standard yields (kg) were 1673, 468, 184, 151, 315, 2260, 7 and 2042, respectively. The daughters of the sire of Umbenein Research Station showed earlier age at first calving and shorter calving interval, open and dry periods, while those of the sire of Umbenein village were higher in lactation, daily and standard yields. Lactation number had significant effects (P≤0.05) on lactation yield, calving interval and open period and were least in the fourth lactation. Daily and standard yields were higher in the third lactation, with a clear drop in the fourth one. Year of calving had significant effects (P≤0.05) on calving interval, open period, daily and standard yields. All traits studied, except lactation period, were higher in 2009-2011 years of calving and decreased in 2012-2014 and 2015-2017 calvings

Wilson’s Disease and Autoimmune Hepatitis Coexistence: A Cause of Diagnostic Delay

This case report describes a 27-year-old housewife who presented with a progressive and insidious onset of abdominal distension, loss of appetite, and fatigue which started 3 months before her presentation. The physical assessment showed moderate ascites and small liver size, and no other peripheral evidence of chronic liver disease was observed. A diagnosis of liver cirrhosis and was confirmed by investigations and imaging, where ascites responded well to therapy with diuretics. Investigations for the cause of cirrhosis was established through the diagnosis of autoimmune hepatitis, and she was started on steroids and azathioprine with partial improvement in liver biochemistry. She presented 8 months later with neuropsychiatric symptoms in the form of slurred speech and difficulty walking. Accordingly, Wilson’s disease was suspected to be the cause and further investigations confirmed this. A chelating agent, D penicillamine, was added to her immunosuppressive treatment. Nine months later she showed slow improvement in her neurological symptoms and was referred for assessment for liver transplantation. Wilson’s disease, although rare, should be suspected in patients with decompensated liver disease. The dominance of clinical and epidemiological features of autoimmune hepatitis as a common causative pathology for chronic liver disease in young and middle-aged ladies may hide the presence of other serious different pathologies such as Wilson’s disease