QoSatAr: a cross-layer architecture for E2E QoS provisioning over DVB-S2 broadband satellite systems

This article presents QoSatAr, a cross-layer architecture developed to provide end-to-end quality of service (QoS) guarantees for Internet protocol (IP) traffic over the Digital Video Broadcasting-Second generation (DVB-S2) satellite systems. The architecture design is based on a cross-layer optimization between the physical layer and the network layer to provide QoS provisioning based on the bandwidth availability present in the DVB-S2 satellite channel. Our design is developed at the satellite-independent layers, being in compliance with the ETSI-BSM-QoS standards. The architecture is set up inside the gateway, it includes a Re-Queuing Mechanism (RQM) to enhance the goodput of the EF and AF traffic classes and an adaptive IP scheduler to guarantee the high-priority traffic classes taking into account the channel conditions affected by rain events. One of the most important aspect of the architecture design is that QoSatAr is able to guarantee the QoS requirements for specific traffic flows considering a single parameter: the bandwidth availability which is set at the physical layer (considering adaptive code and modulation adaptation) and sent to the network layer by means of a cross-layer optimization. The architecture has been evaluated using the NS-2 simulator. In this article, we present evaluation metrics, extensive simulations results and conclusions about the performance of the proposed QoSatAr when it is evaluated over a DVB-S2 satellite scenario. The key results show that the implementation of this architecture enables to keep control of the satellite system load while guaranteeing the QoS levels for the high-priority traffic classes even when bandwidth variations due to rain events are experienced. Moreover, using the RQM mechanism the user’s quality of experience is improved while keeping lower delay and jitter values for the high-priority traffic classes. In particular, the AF goodput is enhanced around 33% over the drop tail scheme (on average)

Polyamines in Human Milk and Their Benefits for Infant Health

Breastfeeding is the gold standard for infant nutrition in the first six months of life when feeding choices determine growth and development. However, human milk is a complex and highly variable fluid that, in addition to nutrients, contains several bioactive components, including polyamines (putrescine, spermidine, and spermine), and constitutes the first exogenous source of these compounds for infants. Active in various cellular processes, polyamines are involved in the growth and maturation of the gastrointestinal tract and the development of the immune system and therefore play an important role in the first year of life. This chapter reviews the impact of polyamines on infant growth and health, the polyamine content in human milk and how it is influenced by factors related to both the mother-child dyad and breastfeeding itself. In addition, a comparative analysis of human milk and infant formulas in terms of polyamine content and profile is presented

Large-eddy simulation sensitivities to variations of configuration and forcing parameters in canonical boundary-layer flows for wind energy applications

The sensitivities of idealized large-eddy simulations (LESs) to variations of model configuration and forcing parameters on quantities of interest to wind power applications are examined. Simulated wind speed, turbulent fluxes, spectra and cospectra are assessed in relation to variations in two physical factors, geostrophic wind speed and surface roughness length, and several model configuration choices, including mesh size and grid aspect ratio, turbulence model, and numerical discretization schemes, in three different code bases. Two case studies representing nearly steady neutral and convective atmospheric boundary layer (ABL) flow conditions over nearly flat and homogeneous terrain were used to force and assess idealized LESs, using periodic lateral boundary conditions. Comparison with fast-response velocity measurements at 10 heights within the lowest 100&thinsp;m indicates that most model configurations performed similarly overall, with differences between observed and predicted wind speed generally smaller than measurement variability. Simulations of convective conditions produced turbulence quantities and spectra that matched the observations well, while those of neutral simulations produced good predictions of stress, but smaller than observed magnitudes of turbulence kinetic energy, likely due to tower wakes influencing the measurements. While sensitivities to model configuration choices and variability in forcing can be considerable, idealized LESs are shown to reliably reproduce quantities of interest to wind energy applications within the lower ABL during quasi-ideal, nearly steady neutral and convective conditions over nearly flat and homogeneous terrain.</p

Coupled mesoscale–microscale modeling of air quality in a polluted city using WRF-LES-Chem

To perform realistic high-resolution air quality modeling in a polluted urban area, the Weather Research and Forecasting (WRF) model is used with an embedded large-eddy simulation (LES) module and online chemistry. As an illustration, a numerical experiment is conducted in the megacity of Hong Kong, which is characterized by multi-type inhomogeneous pollution sources and complex topography. The results from the multi-resolution simulations at mesoscale and LES scales are evaluated by comparing them with ozone sounding profiles and surface observations. The comparisons show that both mesoscale and LES simulations reproduce the mean concentrations of the chemical species and their diurnal variations at the background stations well. However, the mesoscale simulations largely underestimate the NOx concentrations and overestimate O3 at the roadside stations due to the coarse representation of the traffic emissions. The LES simulations improve the agreement with the measurements near the road traffic, and the LES with the highest spatial resolution (33.3 m) provides the best results. The large-eddy simulations show more detailed structures in the spatial distributions of chemical species than the mesoscale simulations, highlighting the capability of LES to resolve high-resolution photochemical transformations in urban areas. Compared to the mesoscale model results, the LES simulations show similar evolutions in the profiles of the chemical species as a function of the boundary layer development over a diurnal cycle.</p

Memoria del I Coloquio de verano de investigación de la Escuela de Negocios de ITESO, 2022

Esta memoria recoge cinco de las ponencias presentadas en el Coloquio de investigación de verano de la ENI, 2022. Son una muestra del trabajo de investigación que hacemos en el Departamento de Economía, Administración y Mercadología (DEAM), en el Centro Universidad Empresa (CUE) y en el Centro para la Gestión de la Innovación y la Tecnología (CEGINT); una investigación con una orientación principalmente práctica y aplicada, enfocada a las micro, pequeñas y medianas empresas y a su contexto socioeconómico. Esperamos que puedan ser ocasión de diálogo y de contribución no sólo al campo académico en el que nos desenvolvemos, sino también a las realidades mismas en las que queremos colaborar para apoyar los esfuerzos hacia una economía y una sociedad más justas y más humanas.ITESO, A.C

Detection of Carbon Monoxide in the Atmosphere of WASP-39b Applying Standard Cross-Correlation Techniques to JWST NIRSpec G395H Data

Carbon monoxide was recently reported in the atmosphere of the hot Jupiter WASP-39b using the NIRSpec PRISM transit observation of this planet, collected as part of the JWST Transiting Exoplanet Community Early Release Science (JTEC ERS) Program. This detection, however, could not be confidently confirmed in the initial analysis of the higher resolution observations with NIRSpec G395H disperser. Here we confirm the detection of CO in the atmosphere of WASP-39b using the NIRSpec G395H data and cross-correlation techniques. We do this by searching for the CO signal in the unbinned transmission spectrum of the planet between 4.6 and 5.0 $\mu$m, where the contribution of CO is expected to be higher than that of other anticipated molecules in the planet's atmosphere. Our search results in a detection of CO with a cross-correlation function (CCF) significance of $6.6 \sigma$ when using a template with only ${\rm ^{12}C^{16}O}$ lines. The CCF significance of the CO signal increases to $7.5 \sigma$ when including in the template lines from additional CO isotopologues, with the largest contribution being from ${\rm ^{13}C^{16}O}$. Our results highlight how cross-correlation techniques can be a powerful tool for unveiling the chemical composition of exoplanetary atmospheres from medium-resolution transmission spectra, including the detection of isotopologues.Comment: Accepted for publication in The Astrophysical Journal Letter

Characterization of germanium detectors for the first underground laboratory in Mexico

This article reports the characterization of two High Purity Germanium detectors performed by extracting and comparing their efficiencies using experimental data and Monte Carlo simulations. The efficiencies were calculated for pointlike γ-ray sources as well as for extended calibration sources. Characteristics of the detectors such as energy linearity, energy resolution and full energy peak efficiencies are reported from measurements performed on surface laboratories. The detectors will be deployed in a γ-ray assay facility that will be located in the first underground laboratory in Mexico, Laboratorio Subterr&apos;aneo de Mineral del Chico (LABChico), in the Comarca Minera UNESCO Global Geopark [1]

Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry.

AIMS: Calmodulinopathy due to mutations in any of the three CALM genes (CALM1-3) causes life-threatening arrhythmia syndromes, especially in young individuals. The International Calmodulinopathy Registry (ICalmR) aims to define and link the increasing complexity of the clinical presentation to the underlying molecular mechanisms. METHODS AND RESULTS: The ICalmR is an international, collaborative, observational study, assembling and analysing clinical and genetic data on CALM-positive patients. The ICalmR has enrolled 140 subjects (median age 10.8 years [interquartile range 5-19]), 97 index cases and 43 family members. CALM-LQTS and CALM-CPVT are the prevalent phenotypes. Primary neurological manifestations, unrelated to post-anoxic sequelae, manifested in 20 patients. Calmodulinopathy remains associated with a high arrhythmic event rate (symptomatic patients, n = 103, 74%). However, compared with the original 2019 cohort, there was a reduced frequency and severity of all cardiac events (61% vs. 85%; P = .001) and sudden death (9% vs. 27%; P = .008). Data on therapy do not allow definitive recommendations. Cardiac structural abnormalities, either cardiomyopathy or congenital heart defects, are present in 30% of patients, mainly CALM-LQTS, and lethal cases of heart failure have occurred. The number of familial cases and of families with strikingly different phenotypes is increasing. CONCLUSION: Calmodulinopathy has pleiotropic presentations, from channelopathy to syndromic forms. Clinical severity ranges from the early onset of life-threatening arrhythmias to the absence of symptoms, and the percentage of milder and familial forms is increasing. There are no hard data to guide therapy, and current management includes pharmacological and surgical antiadrenergic interventions with sodium channel blockers often accompanied by an implantable cardioverter-defibrillator