Plant Products as Biopesticides: Building On Traditional Knowledge of Vrkshayurveda: Traditional Indian Plant Science

Today there is a global search for alternatives to chemical pesticides and as part of this process there are various efforts to test the use and efficacy of natural products for pest control and crop protection. Our Centre has been involved in exploring the traditional knowledge regarding the use of natural products for pest control and crop protection. As part of this effort, we have looked at the traditional folk practices prevalent among farmers as well as information from classical literature on the subject drawn from Vrkshayurveda (traditional Indian plant science). Following this, we have carried out experiments for standardizing and field testing promising natural products by determining the precise range and kind of pests controlled by them, determining the optimum concentration where they can be effective against pests without being harmful to useful organisms and predators as well as studying their mode of action. Subsequently, we have also developed storage forms of various of these products by using methods based on Ayurveda. Studies on the stability and shelf life of these products are also being carried out through an insect rearing laboratory. Finally, we have also set up village based biopesticides units where a range of these products are being prepared thus providing valuable inputs to sustainable agriculture and a means of livelihood to rural women and farmers

NETMAT: A knowledge-based grid system analysis tool

The increasing expansion of electric power systems renders the power system operator's task increasingly complex. The integration into energy management systems of further analytical algorithms implies that more data has to be analysed by the control engineer. For these reasons and many others, more sophisticated tools are required by power engineers to ease the pressure under which they perform their task. The advent of knowledge-based systems has led to a new approach to the problem. The combination of expert systems and numerical algorithms can be advantageously exploited to assist the power system engineer in operating the system. This paper presents the development of a knowledge-based tool for grid system analysis. The tool, NETMAT (NETwork Modelling AssistanT) , is to be used to analyse the impact of grid system maintenance and modification procedures and of new generating plants on power utilities, and in particular on their ability to generate and sell electricity. NE TMAT consists of a number of numerical applications interfaced to an expert system shell through specific problem domain knowledge bases. Results are presented based on the use of the IEEE-30 busbar network as a test network

Deal or no deal: can incentives encourage widespread adoption of intelligent speed adaptation devices?

Given the burden of injury, economic, environmental and social consequences associated with speeding, reducing road traffic speed remains a major priority. Intelligent speed adaptation (ISA) is a promising but controversial new in-vehicle system that provides drivers with support on the speed-control task. In order to model potential system uptake, this paper explores drivers’ preferences for two different types of ISA given a number of alternative fiscal incentives and non-fiscal measures, using a stated preference approach. As would be expected with such a contentious issue, the analysis revealed the presence of significant variations in sensitivities and preferences in the sample. While a non-negligible part of the sample population has such strong opposition to ISA that no reasonable discounts or incentives would lead to them buying or accepting such a system, there is also a large part of the population that, if given the right incentives, would be willing or even keen to equip their vehicle with an ISA device

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

The induction of regulatory T (T reg) cells holds considerable potential as a treatment for autoimmune diseases. We have previously shown that CD4(+)CD25(hi) T reg cells isolated from patients with active rheumatoid arthritis (RA) have a defect in their ability to suppress proinflammatory cytokine production by CD4(+)CD25(-) T cells. This defect, however, was overcome after anti-tumor necrosis factor (TNF)-alpha antibody (infliximab) therapy. Here, we demonstrate that infliximab therapy gives rise to a CD4(+)CD25(hi)FoxP3(+) T reg cell population, which mediates suppression via transforming growth factor (TGF)-beta and interleukin 10, and lacks CD62L expression, thereby distinguishing this T reg cell subset from natural T reg cells present in healthy individuals and patients with active RA. In vitro, infliximab induced the differentiation of CD62L(-) T reg cells from CD4(+)CD25(-) T cells isolated from active RA patients, a process dependent on TGF-alpha. In spite of the potent suppressor capacity displayed by this CD62L(-) T reg cell population, the natural CD62L(+) T reg cells remained defective in infliximab-treated patients. These results suggest that anti-TNF-alpha therapy in RA patients generates a newly differentiated population of T reg cells, which compensates for the defective natural T reg cells. Therefore, manipulation of a proinflammatory environment could represent a therapeutic strategy for the induction of T reg cells and the restoration of tolerance

The Evolution and Diversity of SALMFamide Neuropeptides

The SALMFamides are a family of neuropeptides that act as muscle relaxants in echinoderms. Two types of SALMFamides have been identified: L-type (e.g. the starfish neuropeptides S1 and S2) with the C-terminal motif LxFamide (x is variable) and F-type with the C-terminal motif FxFamide. In the sea urchin Strongylocentrotus purpuratus (class Echinoidea) there are two SALMFamide genes, one encoding L-type SALMFamides and a second encoding F-type SALMFamides, but hitherto it was not known if this applies to other echinoderms. Here we report the identification of SALMFamide genes in the sea cucumber Apostichopus japonicus (class Holothuroidea) and the starfish Patiria miniata (class Asteroidea). In both species there are two SALMFamide genes: one gene encoding L-type SALMFamides (e.g. S1 in P. miniata) and a second gene encoding F-type SALMFamides plus one or more L-type SALMFamides (e.g. S2-like peptide in P. miniata). Thus, the ancestry of the two SALMFamide gene types traces back to the common ancestor of echinoids, holothurians and asteroids, although it is not clear if the occurrence of L-type peptides in F-type SALMFamide precursors is an ancestral or derived character. The gene sequences also reveal a remarkable diversity of SALMFamide neuropeptides. Originally just two peptides (S1 and S2) were isolated from starfish but now we find that in P. miniata, for example, there are sixteen putative SALMFamide neuropeptides. Thus, the SALMFamides would be a good model system for experimental analysis of the physiological significance of neuropeptide "cocktails" derived from the same precursor protein

The exactness of a general Skoda complex

We show that a Skoda complex with a general plurisubharmonic weight function is exact if its 'degree' is sufficiently large. This answers a question of Lazarsfeld and implies that not every integrally closed ideal is equal to a multiplier ideal even if we allow general plurisubharmonic weights for the multiplier ideal, extending the result of Lazarsfeld and Lee \cite{LL}.Comment: References added, exposition streamlined, to appear in Michigan Mathematical Journa

Cu2+ uptake by Chlorococcum hemicolum - A Xeric Chlorophycean Alga

Bioremediation of copper by xeric chlorophycean bioremediator, Chlorococcum hemicolum was investigated. The growth rates at various concentrations of Cu2+ were assessed in terms of protein level and 8 mg L-1 (37.67 % level in growth kinetics) is the tolerance limit. Absorption/adsorption kinetics was estimated after 240 hrs of Cu2+ treatments. Absorptions were higher than adsorption with maximum accumulation factor (AF) of 1.40. The Cu2+ concentration and absorption were linearly related (r = 0.99; p>0.01). Other biochemical parameters like total sugar, chlorophyll and carotenoids were also quantified to correlate the state of metabolism and these exhibited reduction due to heavy metal stress

A critical comparison of approaches to resource name management within the IEC common information model

Copyright @ 2012 IEEEElectricity network resources are frequently identified within different power systems by inhomogeneous names and identities due to the legacy of their administration by different utility business domains. The IEC 61970 Common Information Model (CIM) enables network modeling to reflect the reality of multiple names for unique network resources. However this issue presents a serious challenge to the integrity of a shared CIM repository that has the task of maintaining a resource manifest, linking network resources to master identities, when unique network resources may have multiple names and identities derived from different power system models and other power system applications. The current approach, using CIM 15, is to manage multiple resource names within a singular CIM namespace utilizing the CIM “IdentifiedObject” and “Name” classes. We compare this approach to one using additional namespaces relating to different power systems, similar to the practice used in CIM extensions, in order to more clearly identify the genealogy of a network resource, provide faster model import times and a simpler means of supporting the relationship between multiple resource names and identities and a master resource identity.This study is supported by the UK National Grid and Brunel University

Elm Farm Organic Research Centre Bulletin 83 April 2006

Regular bulleting with technical updates from Organic Advisory Service Issue contains: Testing for Tolerance - a pragmatic view GM Debate Vaccination nation - to jab or not to jab Future shape of OCIS Evolutionary wheat makes the grade? NIAB tracks health of organic cereal seed Stopping erosion of soil quality - the organic way Care needed to halt butterfly collapse Aspects of poultry behaviour: How free range is free range? On choosing an organic wheat A local education challenge New Wakelyns Science Building Organic vegetable market growt