Manual control analysis of drug effects on driving performance

The effects of secobarbital, diazepam, alcohol, and marihuana on car-driver transfer functions obtained using a driving simulator were studied. The first three substances, all CNS depressants, reduced gain, crossover frequency, and coherence which resulted in poorer tracking performance. Marihuana also impaired tracking performance but the only effect on the transfer function parameters was to reduce coherence

Continuous-time link-based kinematic wave model: formulation, solution existence, and well-posedness

We present a continuous-time link-based kinematic wave model (LKWM) for dynamic traffic networks based on the scalar conservation law model. Derivation of the LKWM involves the variational principle for the Hamilton-Jacobi equation and junction models defined via the notions of demand and supply. We show that the proposed LKWM can be formulated as a system of differential algebraic equations (DAEs), which captures shock formation and propagation, as well as queue spillback. The DAE system, as we show in this paper, is the continuous-time counterpart of the link transmission model. In addition, we present a solution existence theory for the continuous-time network model and investigate continuous dependence of the solution on the initial data, a property known as well-posedness. We test the DAE system extensively on several small and large networks and demonstrate its numerical efficiency.Comment: 39 pages, 14 figures, 2 tables, Transportmetrica B: Transport Dynamics 201

Coherently Controlled Nanoscale Molecular Deposition

Quantum interference effects are shown to provide a means of controlling and enhancing the focusing a collimated neutral molecular beam onto a surface. The nature of the aperiodic pattern formed can be altered by varying laser field characteristics and the system geometry.Comment: 13 pages (inculding 4 figures), LaTeX (Phys. Rev. Lett., 2000, in Press

Low Temperature Magnetic Properties of Siderite and Magnetite in Marine Sediments

Low temperature magnetic techniques provide useful tools to detect the presence of magnetite and pyrrhotite in sediments through identification of their low temperature transitions, to determine the amount of ultrafine-grained (superparamagnetic) material in sediments, and can potentially detect the presence of certain types of magnetotactic bacteria. Application of these types of experiments to nannofossil chalks from beneath the Barbados accretionary prism led to some unusual results, which are attributed to the presence of siderite. Thermal demagnetization of low-temperature remanence after cooling in zero field and in a 2.5 T field both displayed large remanence losses from 20 K to 40 K. Below 40 K, the magnetization of the chalks was much higher in the field-cooled experiments than in the zero-field-cooled experiments. Low temperature hysteresis experiments, made after cooling in a 2.5 T field, displayed offsets in magnetization parallel to the direction of the initial applied field, when measured below 40 K. The offset loops can be due to either an exchange anisotropy between siderite and magnetite phases in the sediments, a defect moment in the siderites, or a canted moment in the siderites. Apparent similarity between the low-temperature thermal demagnetization results from these siderite-bearing sediments, pure siderite, and pure rhodochrosite samples and the well-known 34 K transition in pyrrhotite should lead to caution in identification of pyrrhotite in marine sediments based on low-temperature remanence studies alone

Developing and validating an experience sampling measure of aggression:The Aggression-ES Scale

Experience sampling methodologies are likely to play an important role in advancing our understanding of momentary influences on aggression, including short-term antecedent psychological states and situations. In this study, we evaluate whether a newly developed experiencing sampling measure of aggression, the Aggression Experience Sampler (Aggression-ES), provides a valid and reliable measure of aggression in experience sampling contexts. Participants were a convenience sample of 23 young adults recruited from the local University community. Data were collected using an experience sampling smartphone application over 8 days. They were analyzed using multilevel structural equation modeling. Our results support the within- and between-person reliability and the criterion validity of the Aggression-ES. The Aggression-ES represents a good choice of measure for use in experience sampling studies of aggression. Further work in other samples will help to provide further validity evidence for the measure

A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines.

BACKGROUND: ENU-mutagenesis is a powerful technique to identify genes regulating mammalian development. To functionally annotate the distal region of mouse chromosome 4, we performed an ENU-mutagenesis screen using a balancer chromosome targeted to this region of the genome. RESULTS: We isolated 11 lethal lines that map to the region of chromosome 4 between D4Mit117 and D4Mit281. These lines form 10 complementation groups. The majority of lines die during embryonic development between E5.5 and E12.5 and display defects in gastrulation, cardiac development, and craniofacial development. One line displayed postnatal lethality and neurological defects, including ataxia and seizures. CONCLUSION: These eleven mutants allow us to query gene function within the distal region of mouse chromosome 4 and demonstrate that new mouse models of mammalian developmental defects can easily and quickly be generated and mapped with the use of ENU-mutagenesis in combination with balancer chromosomes. The low number of mutations isolated in this screen compared with other balancer chromosome screens indicates that the functions of genes in different regions of the genome vary widely

Measurement of higher cumulants of net-charge multiplicity distributions in Au++Au collisions at sNN=7.7−200\sqrt{s_{_{NN}}}=7.7-200 GeV

We report the measurement of cumulants ($C_n, n=1\ldots4$) of the net-charge distributions measured within pseudorapidity ($|\eta|<0.35$) in Au$+$Au collisions at $\sqrt{s_{_{NN}}}=7.7-200$ GeV with the PHENIX experiment at the Relativistic Heavy Ion Collider. The ratios of cumulants (e.g. $C_1/C_2$, $C_3/C_1$) of the net-charge distributions, which can be related to volume independent susceptibility ratios, are studied as a function of centrality and energy. These quantities are important to understand the quantum-chromodynamics phase diagram and possible existence of a critical end point. The measured values are very well described by expectation from negative binomial distributions. We do not observe any nonmonotonic behavior in the ratios of the cumulants as a function of collision energy. The measured values of $C_1/C_2 = \mu/\sigma^2$ and $C_3/C_1 = S\sigma^3/\mu$ can be directly compared to lattice quantum-chromodynamics calculations and thus allow extraction of both the chemical freeze-out temperature and the baryon chemical potential at each center-of-mass energy.Comment: 512 authors, 8 pages, 4 figures, 1 table. v2 is version accepted for publication in Phys. Rev. C as a Rapid Communication. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.htm