657 research outputs found

    Portraits (with an essay Of Masks & Myself: Notes on the Self-Portraits of February 1983)

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    Barry Moser of West Hatfield, Massachusetts, is a distinguished wood engraver who has done illustrations for special limited editions of Moby Dick, Alice in Wonderland, Frankenstein, Huckleberry Finn, among others

    MODEL SELECTION TECHNIQUES FOR REPEATED MEASURES COVARIANCE STRUCTURES

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    A parsimonious covariance structure of repeated measures is often sought for purposes of increased power for testing hypotheses about the means, and for insight into the stochastic processes governing the repeated measures. For normal data, model selection is often based upon likelihood ratio tests or information criteria derived from the likelihood, sometimes supplemented with graphical plots of correlations and partial correlations. We exploit the ordered nature of repeated measures to decompose the likelihood ratio goodness-of-fit test statistic, and display graphical fingerprints associated with the covariance structures to help detect covariance structure misspecification, in order to provide guidance in choosing an appropriate structure for the data. The proposed methodology is illustrated with simulated repeated measures data and then applied to an experiment to compare tillage methods of pasture establishment

    Soluble RAGE: a hot new biomarker for the hot joint?

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    The receptor for advanced glycation endproducts (RAGE) interacts with distinct ligand families linked to the inflammatory response. Studies in animal models suggest that RAGE is upregulated in the inflamed joint and that blockade of the receptor, using a ligand decoy soluble form of RAGE (sRAGE), attenuates joint inflammation and expression of inflammatory and tissue-destructive mediators. In this issue of Arthritis Research & Therapy, Rille Pullerits and colleagues reported that plasma levels of sRAGE were reduced in subjects with rheumatoid arthritis compared with healthy controls or subjects with non-inflammatory joint disease. These findings suggest the possibility that levels of sRAGE might be a biomarker of inflammation. Not resolved by these studies, however, is the intriguing possibility that endogenously higher levels of sRAGE might be linked to a lower incidence of arthritis or to the extent of inflammation. Nevertheless, although 'cause or effect' relationships may not be established in this report, fascinating insights into RAGE, inflammation and human arthritis emerge from these studies

    A COMPARISON OF SPATIAL PREDICTION METHODS USING INTENSE SPATIALLY-ACQUIRED WATER QUALITY DATA

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    Water quality information obtained through intensive spatial sampling using automated devices provides opportunities to monitor and forecast the spatial distribution of nutrients and phytoplankton concentrations, and help establish water circulation patterns in estuarine and coastal waters. To be cost effective, efficient sampling designs and estimation methodologies must first be developed. As a starting basis, we applied an original transect sampling design that was used to estimate the spatial distribution of chlorophyll a, salinity, and temperature in the Cienaga Grande de Santa Marta, a coastal lagoon in Colombia. We superimposed the transects over satellite images of the lagoon obtained in the period 1993-2001 to evaluate the efficiency and accuracy of using such transects to estimate the distribution of water quality variables. The satellite images were taken in 1993 (SPOT-3), 1995 (Landsat-6), and 1999 (Landsat-6), and water reflectance values were used as a “proxy” for the water quality variables. Spatial prediction using kriging and thin-plate smoothing splines were used to predict reflectance for a grid network of points taken from the images, and predictions were compared with observed values to compare methods and transect routes. Rapid changes in reflectance in short distances (for example , caused by phytoplankton blooms), complicated the analysis, and neither method proved superior over all transect routes and images, although the kriging predictor remained relatively consistent in performance over the various selected sampling routes

    Credit Card Usage of College Students: Evidence from Louisiana State University (Research Information Sheet #107)

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    In recent years, there has been a dramatic growth in credit card usage among college students. How are Louisiana State University undergraduates using credit cards? Are LSU students managing credit card debt wisely? What can LSU do to offer the appropriate kinds of help to enable students to be financially literate? These are the issues addressed in this publication.https://digitalcommons.lsu.edu/agcenter_researchinfosheets/1007/thumbnail.jp

    Glycation and diabetes: The RAGE connection

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    The hyperglycaemic state seen in diabetes mellitus is associated with the development of diabetes-specific microvascular complications and accelerated macrovascular disease. Evidence implicates the formation and subsequent effects of advanced glycation endproducts (AGEs) as a contributing cause. AGEs exert their effects through interaction with the Receptor for AGE (RAGE) which upregulates expression of the receptor and induces a cascade of cytotoxic pathways. Accumulation of AGE/RAGE can be seen at sites of vascular disease in both animal models of diabetes and human diabetic subjects. Blockade of RAGE in animal models of diabetes suppresses development of dysfunction in the vasculature and atherosclerosis development. Genetic studies of RAGE reveal that a number of allelic variants of RAGE occur in key protein and regulatory domains. A Gly to Ser change at position 82 and two 5¢¢ flanking polymorphisms at position –374 and –429 lead to altered function and expression of RAGE which may impact on diabetic vascular disease development. Therapy aimed to block RAGE upregulation may prove to be useful in treating individuals with diabetic vascular disease

    Partner-assisted emotional disclosure for patients with gastrointestinal cancer: Results from a randomized controlled trial

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    For patients with cancer who are married or in an intimate relationship, their relationships with their partners play a critical role in their adaptation to their illness. However, cancer patients and their partners often have difficulty in talking with each other about their cancer-related concerns. Difficulties in communication may ultimately compromise both the patient-partner relationship and the patient's psychological adjustment. The present study tested the efficacy of a novel partner-assisted emotional disclosure intervention in a sample of patients with gastrointestinal (GI) cancer

    The Vehicle, 1965, Vol. 7

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    Vol. 7 Table of Contents CommentaryElaine Lancepage 3 Lost Island and The Unseen SeaDaun Alan Leggpage 5 ElegyWilliam Mosierpage 6 AwayDavid Dixpage 7 DulceyRoberta Mathewspage 8 Alarum Tuam JonneDavid Walkerpage 11 Little BrotherSteve Gibbspage 13 River RunningDaun Alan Leggpage 15 PortraitRobert D. Thomaspage 16 The RockRoger Lewis Hudsonpage 17 Jarman HospitalElaine Lancepage 18 Of Domes and DiamondsDwight Ashbypage 19 Friday NightRoger J. Barrypage 20 MurderHelen Coxpage 23 Vigil SongDaun Alan Leggpage 24 Had You But Been the OneDavid Helmpage 25 To A Useless WeaponDarlene Brewerpage 25 Out of the NightPat Hartpage 26 La MortAdrian Beardpage 28 Mrs. Milton\u27s LamentBob Millerpage 30 Cockle CoveSusan McCabepage 31 Loss of VirtueJim Rinnertpage 32 The KeepsakeDwight Ashbypage 33 The RuinsRoger Lewis Hudsonpage 35 Ante Major OdysseyDaun Alan Leggpage 38 ReligionAnthony Barrettepage 39 All JoyJim Rinnertpage 40 SesameElaine Lancepage 40 CenterpieceDwight Ashbypage 41 A Great White WaveJohn Rhodespage 42 QueryElaine Lancepage 44 PistachioRita Salyerspage 45 FacadeKathleen McCormackpage 46 Winter Wisp AwaySteve Gibbspage 46 ScenarioDavid Dixpage 47 Damn-GodSteve Gibbspage 48 AccidentElaine Lancepage 48https://thekeep.eiu.edu/vehicle/1013/thumbnail.jp

    The Vehicle, Spring 1993

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    1993 Commemorative Edition: Celebrating 35 Years Table of Contents The Vehicle Editors\u27 Lineagepage 5 Milestonespage 6 THE SIXTIES Coverspage 7 Editors\u27 Notespage 8 Sureness is Never - excerptDon Shepardsonpage 9 SophisticationBenjamin Polkpage 10 A SonnetMignon Stricklandpage 11 The Twenty-Third ChannelBen Polkpage 11 Opposite AttractionsC.E.M. (Christine McColl)page 12 John F. KennedyJoel E. Hendrickspage 13 The Girl on the White PonyLarry Gatespage 14 The TimesW.D.M. (William Moser)page 16 Home ThoughtsJane Careypage 17 1966Roger Zulaufpage 18 Nagging ThoughtJanet Andrewspage 18 THE SEVENTIES Coverspage 19 Editors\u27 Notespage 20 RevolutionsSteve Siegelpage 21 UntitledKristine Kirkhampage 23 The Arithmetic ProblemJanice Forbuspage 23 Willie Seeverson Threw a Worm at MeMary Pipekpage 24 a love poem (by approximation)Ted Baldwinpage 25 Night and Summer in Two WorldsBarry Smithpage 26 Story of a Teenage PickleTerry Louis Schultzpage 27 Danny Lonely, Danny WildDevin Brownpage 28 Always TomorrowMary McDanielpage 29 THE EIGHTIES Coverspage 31 Having ChildrenDevon Flesorpage 33 What is Unnatural Is Sometimes MagicAngelique Jenningspage 34 If My Father Were A Writer, He Would Still BuildAngelique Jenningspage 35 Photo AlbumPatrick Peterspage 36 Poet Born in Pearl HarborAngelique Jenningspage 37 The History of High School BasketballPatrick Peterspage 38 Banana BreadGail Bowerpage 39 Cover LetterBob Zordanipage 40 Home MoviesBob Zordanipage 41 MigrationPatrick Peterspage 42 THE NINETIES Ba, Ba, Black SheepVictoria Bennettpage 45 Daily LessonsJennifer Moropage 49 Folding My OwnLaurie Ann Malispage 51 About the Authorspage 53 Editors\u27 Notespage 56https://thekeep.eiu.edu/vehicle/1062/thumbnail.jp
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