An Exploratory Analysis of the Role of Self-Compassion and the Relationship Between Attachment and Body Appreciation

Graduate Applie

Corona Poem

Simple poem about how the coronavirus has made me feel.https://digitalcommons.longwood.edu/covid19/1052/thumbnail.jp

Addicted Youth: The Understanding Of Smoking-Related Health Risks In Female College Students

Young adults are at the greatest risk for initiation of smoking or becoming daily smokers. Smoking has a unique history in the United States and is associated with health risks beyond heart disease and lung cancer, many specifically affecting women. Although the majority of people are aware of the risks for heart disease and lung cancer, many other risks are not recognized. By evaluating the known knowledge of smoking-related health risks beyond and including heart disease and lung cancer in the high risk population of female college students, education programs and cessation teaching can be altered, potentially resulting in lower start rates and higher cessation rates. In order to accomplish these changes, known health risks and unknown or unrecognized health risks need to be identified. Data were analyzed using comparative descriptive statistics gathered by a survey tool that was dispersed to college students\u27 email as a Survey Monkey questionnaire. All female students attending Minnesota State University, Mankato during the previous spring 2011, current summer 2011 and upcoming fall 2011 semesters received the email request. Data were included from 473 students aged 18 to 24. Questions addressed personal and family experience with smoking, current smoking status, perceived risk of smoking-related health conditions, participation in high-risk behaviors, and identification of the three most common health consequences of smoking. As indicated by previous research, the majority of current and former smokers began smoking between the ages of 16 and 19. The data corroborated with previous studies indicating low perceived risk for smoking-related health conditions. Correlations between participation in high-risk behaviors and tobacco use were supported by the research. Positive family history with smoking-related health consequence appears to be a factor in tobacco use. Results from this study duplicate previous research indicating the health care system\u27s failure in making advances in educating young women about smoking-related health risks. Additionally, the media\u27s attempts at educating the public of the link between smoking and heart disease in women has failed with over 75% of respondents incorrectly identifying lung cancer as the most common health consequence of smoking. A need for assessment of the smoking status of and education regarding the health risks of tobacco use is indicated by the results

An investigation of alcohol consumption in North Queensland: an application of the prototype willingness model

Background/Aims: The prototype willingness (PW) model suggests that there are two separate antecedents to behaviour: intention and willingness. Whereas intention is suggested to be reasoned and deliberative, willingness is more automatic and reactive. The aim of this study was to assess alcohol consumption in an Australian sample as well as the antecedents to drinking behaviour on both weekdays and weekend days. Methods: The sample for this study was taken from a larger cross-cultural study (n=371); however only those who identified as Australian were included in the current analysis. From the original sample, 177 participants identified as Australian (115 females and 62 males). Participants completed a questionnaire assessing demographic variables, alcohol consumption and variables on the PW model. Results: Participants reported consuming more alcohol during weekend drinking sessions (M = 5.60, SD = 4.80) than weekday drinking sessions (M = 1.46, SD = 2.49). The model accounted for 15.0% of the variance in the quantity of alcohol consumed in a typical weekday drinking session and 41.5% of the variance in a typical weekend drinking session. Willingness to drink significantly predicted alcohol consumption during weekday drinking sessions. Both willingness and intention to drink, and demographic variables significantly predicted alcohol consumption during weekend drinking sessions. Conclusion: The antecedents of the PW model differentially predicted alcohol consumption during a typical weekday and weekend drinking session

Effective ecosystem monitoring requires a multi-scaled approach

Ecosystem monitoring is fundamental to our understanding of how ecosystem change is impacting our natural resources and is vital for developing evidence-based policy and management. However, the different types of ecosystem monitoring, along with their recommended applications, are often poorly understood and contentious. Varying definitions and strict adherence to a specific monitoring type can inhibit effective ecosystem monitoring, leading to poor program development, implementation and outcomes. In an effort to develop a more consistent and clear understanding of ecosystem monitoring programs, we here review the main types of monitoring and recommend the widespread adoption of three classifications of monitoring, namely, targeted, surveillance and landscape monitoring. Landscape monitoring is conducted over large areas, provides spatial data, and enables questions relating to where and when ecosystem change is occurring to be addressed. Surveillance monitoring uses standardised field methods to inform on what is changing in our environments and the direction and magnitude of that change, whilst targeted monitoring is designed around testable hypotheses over defined areas and is the best approach for determining the causes of ecosystem change. The classification system is flexible and can incorporate different interests, objectives, targets and characteristics as well as different spatial scales and temporal frequencies, while also providing valuable structure and consistency across distinct ecosystem monitoring programs. To support our argument, we examine the ability of each monitoring type to inform on six key types of questions that are routinely posed for ecosystem monitoring programs, such as where and when change is occurring, what is the magnitude of change, and how can the change be managed? As we demonstrate, each type of ecosystem monitoring has its own strengths and weaknesses, which should be carefully considered relative to the desired results. Using this scheme, scientists and land managers can design programs best suited to their needs. Finally, we assert that for our most serious environmental challenges, it is essential that we include information from each of these monitoring scales to inform on all facets of ecosystem change, and this is best achieved through close collaboration between the scales. With a renewed understanding of the importance of each monitoring type, along with greater commitment to monitor cooperatively, we will be well placed to address some of our greatest environmental challenges

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.

The mammalian target of rapamycin (mTOR) is a critical regulator of cell growth, integrating multiple signalling cues and pathways. Key among the downstream activities of mTOR is the control of the protein synthesis machinery. This is achieved, in part, via the co-ordinated regulation of mRNAs that contain a terminal oligopyrimidine tract (TOP) at their 5'ends, although the mechanisms by which this occurs downstream of mTOR signalling are still unclear. We used RNA-binding protein (RBP) capture to identify changes in the protein-RNA interaction landscape following mTOR inhibition. Upon mTOR inhibition, the binding of LARP1 to a number of mRNAs, including TOP-containing mRNAs, increased. Importantly, non-TOP-containing mRNAs bound by LARP1 are in a translationally-repressed state, even under control conditions. The mRNA interactome of the LARP1-associated protein PABPC1 was found to have a high degree of overlap with that of LARP1 and our data show that PABPC1 is required for the association of LARP1 with its specific mRNA targets. Finally, we demonstrate that mRNAs, including those encoding proteins critical for cell growth and survival, are translationally repressed when bound by both LARP1 and PABPC1

Targeting the PAI-1 Mechanism with a Small Peptide Increases the Efficacy of Alteplase in a Rabbit Model of Chronic Empyema

The incidence of empyema is increasing and associated with a mortality rate of 20% in patients older than 65 years. Since 30% of patients with advanced empyema have contraindications to surgical treatment, novel, low-dose, pharmacological treatments are needed. A Streptococcus pneumoniae-induced rabbit model of chronic empyema recapitulates the progression, loculation, fibrotic repair, and pleural thickening of human disease. Treatment with single chain (sc) urokinase (scuPA) or tissue type (sctPA) plasminogen activators in doses 1.0–4.0 mg/kg were only partially effective in this model. Docking Site Peptide (DSP; 8.0 mg/kg), which decreased the dose of sctPA for successful fibrinolytic therapy in acute empyema model did not improve efficacy in combination with 2.0 mg/kg scuPA or sctPA. However, a two-fold increase in either sctPA or DSP (4.0 and 8.0 mg/kg or 2.0 and 16.0 mg/kg sctPA and DSP, respectively) resulted in 100% effective outcome. Thus, DSP-based Plasminogen Activator Inhibitor 1-Targeted Fibrinolytic Therapy (PAI-1-TFT) of chronic infectious pleural injury in rabbits increases the efficacy of alteplase rendering ineffective doses of sctPA effective. PAI-1-TFT represents a novel, well-tolerated treatment of empyema that is amenable to clinical introduction. The chronic empyema model recapitulates increased resistance of advanced human empyema to fibrinolytic therapy, thus allowing for studies of muti-injection treatments