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Further shock tunnel studies of scramjet phenomena
Scramjet phenomena were studied using the shock tunnel T3 at the Australian National University. Simple two dimensional models were used with a combination of wall and central injectors. Silane as an additive to hydrogen fuel was studied over a range of temperatures and pressures to evaluate its effect as an ignition aid. The film cooling effect of surface injected hydrogen was measured over a wide range of equivalence. Heat transfer measurements without injection were repeated to confirm previous indications of heating rates lower than simple flat plate predictions for laminar boundary layers in equilibrium flow. The previous results were reproduced and the discrepancies are discussed in terms of the model geometry and departures of the flow from equilibrium. In the thrust producing mode, attempts were made to increase specific impulse with wall injection. Some preliminary tests were also performed on shock induced ignition, to investigate the possibility in flight of injecting fuel upstream of the combustion chamber, where it could mix but not burn
Scramjet sidewall burning: Preliminary shock tunnel results
Experiments performed with a two dimensional model scramjet with particular emphasis on the effect of fuel injection from a wall are reported. Air low with a nominal Mach number of 3.5 and varied enthalpies was produced. It was found that neither hydrogen injection angle nor combustor divergence angle had any appreciable effect on thrust values while increased combustor length appeared to increase thrust levels. Specific impulse was observed to peak when hydrogen was injected at an equivalence ratio of about 2. Lowering the Mach number of the injected hydrogen at low equivalence ratios, less than 4, appeared to benefit specific impulse while hydrogen Mach number had little effect at higher equivalence ratios. When a 1:1 mixture by volume of nitrogen and oxygen is used instead of air as a test gas, it is found that hydrogen combustion is enhanced but only at high enthalpies
Electrically driven convection in a thin annular film undergoing circular Couette flow
We investigate the linear stability of a thin, suspended, annular film of
conducting fluid with a voltage difference applied between its inner and outer
edges. For a sufficiently large voltage, such a film is unstable to
radially-driven electroconvection due to charges which develop on its free
surfaces. The film can also be subjected to a Couette shear by rotating its
inner edge. This combination is experimentally realized using films of smectic
A liquid crystals. In the absence of shear, the convective flow consists of a
stationary, azimuthally one-dimensional pattern of symmetric, counter-rotating
vortex pairs. When Couette flow is applied, an azimuthally traveling pattern
results. When viewed in a co-rotating frame, the traveling pattern consists of
pairs of asymmetric vortices. We calculate the neutral stability boundary for
arbitrary radius ratio and Reynolds number of the shear
flow, and obtain the critical control parameter and the critical azimuthal mode number . The
Couette flow suppresses the onset of electroconvection, so that . The calculated suppression is
compared with experiments performed at and .Comment: 17 pages, 2 column with 9 included eps figures. See also
http://mobydick.physics.utoronto.c
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An Apparent Relation between ELM Occurrence Times and the Prior Evolution of Divertor Flux Loop Measurements in JET
A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain
BACKGROUND: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients. The purpose of this study is to identify genetic factors contributing to this type of pain in a general diabetic population. METHOD: We accessed the Genetics of Diabetes Audit and Research Tayside (GoDARTS) datasets that contain prescription information and monofilament test results for 9439 diabetic patients, among which 6927 diabetic individuals were genotyped by Affymetrix SNP6.0 or Illumina OmniExpress chips. Cases of neuropathic pain were defined as diabetic patients with a prescription history of at least one of five drugs specifically indicated for the treatment of neuropathic pain and in whom monofilament test result was positive for sensory neuropathy in at least one foot. Controls were individuals who did not have a record of receiving any opioid analgesics. Imputation of non‐genotyped SNPs was performed by IMPUTE2, with reference files from 1000 Genomes Phase I datasets. RESULTS: After data cleaning and relevant exclusions, imputed genotypes of 572 diabetic neuropathic pain cases and 2491 diabetic controls were used in the Fisher's exact test. We identified a cluster in the Chr8p21.3, next to GFRA2 with a lowest p‐value of 1.77 × 10(−7) at rs17428041. The narrow‐sense heritability of this phenotype was 11.00%. CONCLUSION: This genome‐wide association study on diabetic neuropathic pain suggests new evidence for the involvement of variants near GFRA2 with the disorder, which needs to be verified in an independent cohort and at the molecular level
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