14 research outputs found
Indication for Endoscopic Resection of Submucosal Colorectal Carcinoma: Special Reference to Lymph Node Metastasis
We investigated the relationship between histological factors and lymph node metastasis in
77 lesions with submucosally invasive colorectal carcinomas to establish useful criteria for
lesions in which endoscopic treatment alone results in cure of malignancy. There were positive
correlations between histological factors, including the level of invasion, the histologic grade,
presence or absence of lymphatic invasion, presence or absence of budding, and lymph node
metastasis (p < 0.05, p < 0.05, p < 0.005, p < 0.01). The presence or absence of venous
invasion did not influence lymph node metastasis. Laparoscopic surgery involving lymph node
dissection should be indicated for sm1 carcinoma lesions with unfavorable histological factors.
In lesions diagnosed as sm2 or sm3 prior to resection, intestinal resection involving lymph node
dissection by laparoscopic surgery should be directly performed without endoscopic resection