1,720 research outputs found
Exploring quantum chaos with a single nuclear spin
Most classical dynamical systems are chaotic. The trajectories of two
identical systems prepared in infinitesimally different initial conditions
diverge exponentially with time. Quantum systems, instead, exhibit
quasi-periodicity due to their discrete spectrum. Nonetheless, the dynamics of
quantum systems whose classical counterparts are chaotic are expected to show
some features that resemble chaotic motion. Among the many controversial
aspects of the quantum-classical boundary, the emergence of chaos remains among
the least experimentally verified. Time-resolved observations of quantum
chaotic dynamics are particularly rare, and as yet unachieved in a single
particle, where the subtle interplay between chaos and quantum measurement
could be explored at its deepest levels. We present here a realistic proposal
to construct a chaotic driven top from the nuclear spin of a single donor atom
in silicon, in the presence of a nuclear quadrupole interaction. This system is
exquisitely measurable and controllable, and possesses extremely long intrinsic
quantum coherence times, allowing for the observation of subtle dynamical
behavior over extended periods. We show that signatures of chaos are expected
to arise for experimentally realizable parameters of the system, allowing the
study of the relation between quantum decoherence and classical chaos, and the
observation of dynamical tunneling.Comment: revised and published versio
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Exposure to Perfluoroalkyl Substances in a Cohort of Women Firefighters and Office Workers in San Francisco.
Studies of firefighters have shown increased exposures to carcinogenic compounds and elevated rates of certain cancers compared to the general population, yet this research has focused almost exclusively on men. To address this gap, the Women Firefighters Biomonitoring Collaborative created a biological sample archive and analyzed levels of perfluoroalkyl substances (PFAS) among women firefighters (N = 86) and office workers (N = 84) in San Francisco. Serum samples were collected and analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to measure and compare PFAS levels between firefighters and office workers. 7 of 12 PFAS congeners were detected in the least 70% of the study population, and 4 congeners were detected in 100% of participants. In regression models comparing PFAS levels by occupation and adjusting for potential confounders, firefighters had higher geometric mean concentrations of PFAS compared to office workers PFHxS (2.22 (95% CI = 1.55, 3.18)), PFUnDA (1.83 (95% CI = 0.97, 3.45)), and PFNA (1.26 (95% CI = 1.01, 1.58)). Among firefighters, occupational position predicted exposure-firefighters and officers had higher PFNA, PFOA, PFDA, and PFUnDA levels compared to drivers. Women firefighters are exposed to higher levels of some PFAS compared to office workers, suggesting that some of these exposures may be occupationally related
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Integrating Exposure Knowledge and Serum Suspect Screening as a New Approach to Biomonitoring: An Application in Firefighters and Office Workers.
Firefighters (FF) are exposed to recognized and probable carcinogens, yet there are few studies of chemical exposures and associated health concerns in women FFs, such as breast cancer. Biomonitoring often requires a priori selection of compounds to be measured, and so, it may not detect relevant, lesser known, exposures. The Women FFs Biomonitoring Collaborative (WFBC) created a biological sample archive and conducted a general suspect screen (GSS) to address this data gap. Using liquid chromatography-quadrupole time-of-flight tandem mass spectrometry, we sought to identify candidate chemicals of interest in serum samples from 83 women FFs and 79 women office workers (OW) in San Francisco. We identified chemical peaks by matching accurate mass from serum samples against a custom chemical database of 722 slightly polar phenolic and acidic compounds, including many of relevance to firefighting or breast cancer etiology. We then selected tentatively identified chemicals for confirmation based on the following criteria: (1) detection frequency or peak area differences between OW and FF; (2) evidence of mammary carcinogenicity, estrogenicity, or genotoxicity; and (3) not currently measured in large biomonitoring studies. We detected 620 chemicals that matched 300 molecular formulas in the WFBC database, including phthalate metabolites, phosphate flame-retardant metabolites, phenols, pesticides, nitro and nitroso compounds, and per- and polyfluoroalkyl substances. Of the 20 suspect chemicals selected for validation, 8 were confirmed-including two alkylphenols, ethyl paraben, BPF, PFOSAA, benzophenone-3, benzyl p-hydroxybenzoate, and triphenyl phosphate-by running a matrix spike of the reference standards and using m/z, retention time, and the confirmation of at least two fragment ions as criteria for matching. GSS provides a powerful high-throughput approach to identify and prioritize novel chemicals for biomonitoring and health studies
MeerTRAP: Twelve Galactic fast transients detected in a real-time, commensal MeerKAT survey
MeerTRAP is a real-time untargeted search project using the MeerKAT telescope
to find single pulses from fast radio transients and pulsars. It is performed
commensally with the MeerKAT large survey projects (LSPs), using data from up
to 64 of MeerKAT's 13.96~m dishes to form hundreds of coherent beams on sky,
each of which is processed in real time to search for millisecond-duration
pulses. We present the first twelve Galactic sources discovered by MeerTRAP,
with DMs in the range of 33--381~pc~cm. One source may be Galactic or
extragalactic depending on the Galactic electron density model assumed.
Follow-up observations performed with the MeerKAT, Lovell, and Parkes radio
telescopes have detected repeat pulses from seven of the twelve sources. Pulse
periods have been determined for four sources. Another four sources could be
localised to the arcsecond-level using a novel implementation of the tied-array
beam localisation method.Comment: 16 pages, 14 figure
A fast radio burst with a low dispersion measure
Fast radio bursts (FRBs) are millisecond pulses of radio emission of
seemingly extragalactic origin. More than 50 FRBs have now been detected, with
only one seen to repeat. Here we present a new FRB discovery, FRB 110214, which
was detected in the high latitude portion of the High Time Resolution Universe
South survey at the Parkes telescope. FRB 110214 has one of the lowest
dispersion measures of any known FRB (DM = 168.90.5 pc cm), and was
detected in two beams of the Parkes multi-beam receiver. A triangulation of the
burst origin on the sky identified three possible regions in the beam pattern
where it may have originated, all in sidelobes of the primary detection beam.
Depending on the true location of the burst the intrinsic fluence is estimated
to fall in the range of 50 -- 2000 Jy ms, making FRB 110214 one of the
highest-fluence FRBs detected with the Parkes telescope. No repeating pulses
were seen in almost 100 hours of follow-up observations with the Parkes
telescope down to a limiting fluence of 0.3 Jy ms for a 2-ms pulse. Similar
low-DM, ultra-bright FRBs may be detected in telescope sidelobes in the future,
making careful modeling of multi-beam instrument beam patterns of utmost
importance for upcoming FRB surveys.Comment: 8 pages, 3 figures, accepted for publication in MNRA
Navigating the 16-dimensional Hilbert space of a high-spin donor qudit with electric and magnetic fields
Efficient scaling and flexible control are key aspects of useful quantum
computing hardware. Spins in semiconductors combine quantum information
processing with electrons, holes or nuclei, control with electric or magnetic
fields, and scalable coupling via exchange or dipole interaction. However,
accessing large Hilbert space dimensions has remained challenging, due to the
short-distance nature of the interactions. Here, we present an atom-based
semiconductor platform where a 16-dimensional Hilbert space is built by the
combined electron-nuclear states of a single antimony donor in silicon. We
demonstrate the ability to navigate this large Hilbert space using both
electric and magnetic fields, with gate fidelity exceeding 99.8% on the nuclear
spin, and unveil fine details of the system Hamiltonian and its susceptibility
to control and noise fields. These results establish high-spin donors as a rich
platform for practical quantum information and to explore quantum foundations.Comment: 31 pages and 19 figures including Supplementary Material
Acceptability of the 6-PACK falls prevention program: A pre-implementation study in hospitals participating in a cluster randomized controlled trial
There is limited evidence to support the effectiveness of falls prevention interventions in the acute hospital setting. The 6-PACK falls prevention program includes a fall-risk tool; 'falls alert' signs; supervision of patients in the bathroom; ensuring patients' walking AIDS are within reach; toileting regimes; low-low beds; and bed/chair alarms. This study explored the acceptability of the 6-PACK program from the perspective of nurses and senior staff prior to its implementation in a randomised controlled trial. A mixed-methods approach was applied involving 24 acute wards from six Australian hospitals. Participants were nurses working on participating wards and senior hospital staff including: Nurse Unit Managers; senior physicians; Directors of Nursing; and senior personnel involved in quality and safety or falls prevention. Information on program acceptability (suitability, practicality and benefits) was obtained by surveys, focus groups and interviews. Survey data were analysed descriptively, and focus group and interview data thematically. The survey response rate was 60%. Twelve focus groups (n = 96 nurses) and 24 interviews with senior staff were conducted. Falls were identified as a priority patient safety issue and nurses as key players in falls prevention. The 6-PACK program was perceived to offer practical benefits compared to current practice. Nurses agreed fall-risk tools, low-low beds and alert signs were useful for preventing falls (>70%). Views were mixed regarding positioning patients' walking aid within reach. Practical issues raised included access to equipment; and risk of staff injury with low-low bed use. Bathroom supervision was seen to be beneficial, however not always practical. Views on the program appropriateness and benefits were consistent across nurses and senior staff. Staff perceived the 6-PACK program as suitable, practical and beneficial, and were open to adopting the program. Some practical concerns were raised highlighting issues to be addressed by the implementation plan
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