FVV Live: A real-time free-viewpoint video system with consumer electronics hardware

FVV Live is a novel end-to-end free-viewpoint video system, designed for low cost and real-time operation, based on off-the-shelf components. The system has been designed to yield high-quality free-viewpoint video using consumer-grade cameras and hardware, which enables low deployment costs and easy installation for immersive event-broadcasting or videoconferencing. The paper describes the architecture of the system, including acquisition and encoding of multiview plus depth data in several capture servers and virtual view synthesis on an edge server. All the blocks of the system have been designed to overcome the limitations imposed by hardware and network, which impact directly on the accuracy of depth data and thus on the quality of virtual view synthesis. The design of FVV Live allows for an arbitrary number of cameras and capture servers, and the results presented in this paper correspond to an implementation with nine stereo-based depth cameras. FVV Live presents low motion-to-photon and end-to-end delays, which enables seamless free-viewpoint navigation and bilateral immersive communications. Moreover, the visual quality of FVV Live has been assessed through subjective assessment with satisfactory results, and additional comparative tests show that it is preferred over state-of-the-art DIBR alternatives

Influence of the surfactant degree of oligomerization on the formation of cyclodextrin: surfactant inclusion complexes

Supramolecular complexation is an attractive strategy to modulate the performance of surfactants, e.g., by host-guest interactions. Here, we investigate the interaction of single-chained, di-, tri-, and tetrameric cationic surfactants with cyclodextrins by conductivity and 1H NMR measurements, exploring the effect of increasing the number of the surfactant hydrophobic tails on the stability of cyclodextrin:surfactant inclusion complexes. The stoichiometry and the binding equilibrium constants of the different inclusion complexes were elucidated. Under the working conditions, the number of hydrophobic chains was found not to affect stoichiometry and 1:1 inclusion complexes were formed for all the surfactants investigated. The stability of the host-guest complexes decreases from single-chained to dimeric (“gemini”) surfactants, the binding following a non-cooperative mechanism. This result may be rationalized by taking into account steric constraints and electrostatic effects as well as the need to overcome the hydrophobic interactions between the chains of the same surfactant molecule. However, a further increase in the number of hydrophobic tails, from two to three to four, results in an increase in the equilibrium binding constant, K1. In this case, an increment in the number of chains capable of interaction with the cyclodextrin molecules seems to be the main factor responsible for the increase in K1. ROESY spectra show the coexistence of different types of 1:1 host-guest complexes for tri- and tetrameric surfactants.Consejería de Innovación, Ciencia y Empresa de la Junta de Andalucía P12-FQM- 1105, FQM-274 y FQM-206University of Seville 2017/1004FEDER fund

Creación de un cibermedio sobre periodismo: "Académica_mente”

Depto. de Periodismo y Comunicación GlobalDepto. de Periodismo y Nuevos MediosFac. de Ciencias de la InformaciónFALSEsubmitte

Innovación docente en la asignatura Formación del Derecho Común Europeo”. Elaboración de materiales de prácticas

Estudio comparado y elaboración de materiales prácticos diseñados para la docencia bimodal de la asignatura “Formación del Derecho Común Europeo” en el nuevo Plan de estudios del Grado en Derecho de la Universidad Complutense, curso 2020-2021

Evaluation of the effects of a hydrogen sulfide donor on neural plasticity.

The aging brain can exhibit significant modifications related with a progressive atrophy. Previous studies have shown that this atrophy may result from a combination of dendritic regression and neuronal death (1). Age-related memory and cognitive decline have been shown to coincide frequently with morphological changes which affect the neural plasticity and number of dendritic spines in the brains of both humans and animals (2). Furthermore, many neuropathologic conditions and neurodegenerative diseases exhibit abnormalities in dendritic tree structure. Animal studies have shown that even mild prolonged stress has been observed to induce the shrinkage of dendritic fields and the loss of dendritic spines (3).Recent evidence suggest that H2S is a gasotransmitter with neuroprotective properties. In addition, a few sulfur donors have shown beneficial therapeutic effects in experimental models of neurodegenerative diseases (4). Moreover, previous research in our lab suggests that a pharmacological treatment aimed at increasing intracellular H2S improves physical and metabolic health in mice. Nonetheless, the specific properties of these compounds maintaining neuron homeostasis and plasticity remain unknown.Here we aim to investigate whether modulation of intracellular H2S by a pharmacological intervention can improve neuronal plasticity in terms of morphological changes at the level of dendritic arborization and dendritic spine density. To this purpose, we will perform analyses in murine primary neuron cultures that will be treated with increasing concentrations of drug “δ”. Experimental conditions will be: untreated (0, vehicle solution), 10 μM, 50 μM, and 100 μM. Cells will be maintained for 12-14 days in culture, and will be treated with compound “δ” for 48 hours. Then cells will be fixed and MAP2 immunocytochemistry analyses will be performed. Photos will be taken under a fluorescence microscope and analyzed using software ImageJ to determine the percentage of arborized area and the dendritic spine density. The results will provide us with an insight into the potential of drug “δ” as a neuroprotective agent to prevent age-related loss of neuroplasticity

Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging

19 Páginas.-- 7 FigurasATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein, carbohydrate, and lipid metabolism. The physiological consequences as well as the molecular mechanisms orchestrating the response to long-term pharmacologically induced Acly inhibition are unknown. We report here that the Acly inhibitor SB-204990 improves metabolic health and physical strength in wild-type mice when fed with a high-fat diet, while in mice fed with healthy diet results in metabolic imbalance and moderated insulin resistance. By applying a multiomic approach using untargeted metabolomics, transcriptomics, and proteomics, we determined that, in vivo, SB-204990 plays a role in the regulation of molecular mechanisms associated with aging, such as energy metabolism, mitochondrial function, mTOR signaling, and folate cycle, while global alterations on histone acetylation are absent. Our findings indicate a mechanism for regulating molecular pathways of aging that prevents the development of metabolic abnormalities associated with unhealthy dieting. This strategy might be explored for devising therapeutic approaches to prevent metabolic diseases.This work was funded by grants from the Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, co-funded by Fondos FEDER (PI15/00134, PI18/01590, CPII19/00023 to A.M.M.) and the Ministerio de Ciencia e Innovación (PID2021-123965OB-100 to A.M.M.). A.M.M. is funded by the Junta de Andalucía P20_00480, the Spanish Society of Diabetes, and CSIC 202220I059. M.S.K. is funded by the Nordea Foundation (#02-2017-1749), the Novo Nordisk Foundation (#NNF17OC0027812), the Neye Foundation, the Lundbeck Foundation (#R324-2019-1492), the Ministry of Higher Education and Science of Denmark (#0238-00003B). V.C.G. is funded by the Instituto de Salud Carlos III (CP19/00046), co-funded by FEDER. F.M. is funded by the CIBERDEM of the Instituto de Salud Carlos III. A.M.M. is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. We acknowledge the support of the group of basic research on diabetes of the Spanish Society of Diabetes.Peer reviewe

Innovación docente en asignaturas del nuevo plan de estudios del Grado en Derecho

Memoria final del proyecto de innnovación docent

Nuevas dimensiones de la docencia sobre Derecho y factor religioso: interdisciplinariedad y cooperación internacional

Depto. de Derecho Internacional, Eclesiástico y Filosofía del DerechoFac. de DerechoFALSEsubmitte

Nutrición parenteral domiciliaria en España, 2019: informe del Grupo de Nutrición Artificial Domiciliaria y Ambulatoria NADYA

RESUMEN Objetivo: comunicar los datos de nutrición parenteral domiciliaria (NPD) obtenidos del registro del grupo NADYA-SENPE (www.nadyasenpe.com) del año 2019. Material y métodos: análisis descriptivo de los datos recogidos de pacientes adultos y pediátricos con NPD en el registro NADYA-SENPE desde el 1 de enero al 31 de diciembre de 2019. Resultados: se registraron 283 pacientes (51,9 %, mujeres), 31 niños y 252 adultos procedentes de 47 hospitales españoles, lo que representa una tasa de prevalencia de 6,01 pacientes/millón de habitantes/año 2019. El diagnóstico más frecuente en los adultos fue “oncológico paliativo” y “otros” (21,0 %). En los niños fue la enfermedad de Hirschsprung junto a la enterocolitis necrotizante, las alteraciones de la motilidad intestinal y la pseudoobstrucción intestinal crónica, con 4 casos cada uno (12,9 %). El primer motivo de indicación fue el síndrome del intestino corto tanto en los niños (51,6 %) como en los adultos (37,3 %). El tipo de catéter más utilizado fue el tunelizado tanto en los niños (75,9 %) como en los adultos (40,8 %). Finalizaron 68 episodios, todos en adultos: la causa más frecuente fue el fallecimiento (54,4 %). Pasaron a la vía oral el 38,2 %. Conclusiones: el número de centros y profesionales colaboradores con el registro NADYA va incrementándose. Se mantienen estables las principales indicaciones y los motivos de finalización de la NPD

Nuevas dimensiones de la docencia sobre Derecho y factor religioso II: buenas prácticas y elaboración de materiales docentes

Depto. de Derecho Internacional, Eclesiástico y Filosofía del DerechoFac. de DerechoFALSEsubmitte