Inter-dimensional Degeneracies in van der Waals Clusters and Quantum Monte Carlo Computation of Rovibrational States

Quantum Monte Carlo estimates of the spectrum of rotationally invariant states of noble gas clusters suggest inter-dimensional degeneracy in $N-1$ and $N+1$ spacial dimensions. We derive this property by mapping the Schr\"odinger eigenvalue problem onto an eigenvalue equation in which $D$ appears as a continuous variable. We discuss implications for quantum Monte Carlo and dimensional scaling methods

The legal consequences of gender reassignment procedures - A juristic vacuum

No Abstract

Negotiating requests for reimbursement for community engagement: challenges in developing an educational video for genomic biobanking research in South Africa

Genomic research and the biobanking capacity it requires are experiencing considerable growth on the continent of Africa. However genomic research and biobanking raise a range of legal, ethical, social, and cultural issues, including concerns about broad consent, confidentiality, community stigmatization, discrimination, indefinite storage, and long-term use. There is a need to establish governance frameworks that address these issues, and many international health research ethics and biobanking guidelines now recommend that the best way to do so is by involving potential research participants and key community stakeholders in the research development and the process of acquiring samples and data through active community engagement (CE). This article describes the experience and challenges in developing an educational tool as part of a CE initiative in South Africa and the commentaries reflect on how this process may be improved going forward

Takayasu's disease and pregnancy: Three case studies and a review of the literature

Takayasu's disease is commonest in women of childbearing age. Obstetricians are therefore faced with the dilemma of optimal management in pregnancy. This report of 3 cases suggests that Takayasu's disease is associated with a good maternal and fetal outcome. The basic disease appears to be unaffected by pregnancy

Comparison of educational facilitation approaches for Grade R English Additional Language learning in rural Mpumalanga

The Early Childhood Development Manager in Mpumalanga is faced with the problem of providing evidence-based guidance of the best facilitation approach in the Grade R context. An investigation on the effect of   facilitation, i.e. play-based or formal instruction, on Grade R performance scores in English Additional Language (EAL) learning was conducted.  Literature findings attest to formal learning contributing to better   performance scores than play-based learning, yet most rural schools in Mpumalanga use the play-based approach. The English Language Proficiency (ELP) standards assessment tool is reported to have no cultural bias and was used to collect the data. The tool assessed learners’ listening and speaking skills in EAL. A quantitative methodology was followed, using a static two-group comparison design. Participants in the two groups were matched according to age and all had a similar exposure period to EAL learning, a rural upbringing, poverty level, and all were mainstream  learners. Inter-rater reliability was obtained since two raters assessed learners’ proficiency in EAL skills. A one-way Analysis of Variance (ANOVA) was used to analyse the data. It was found that the formal based approach contributed to better EAL scores when compared to the play-based  approach. Implications for practice are discussed.Keywords: EAL learning; ELP standards assessment tool; formal  instruction;Grade R facilitation; learners’ first language; play-based approach

Environmental causes and impacts of the genocide in Rwanda: Case studies of the towns of Butare and Cyangugu

The history of the world has always been punctuated by cycles of violence,regardless of time, region or race. Genocide, which is one of the worst forms of violence, has always led to horrific socio-economic and environmental impacts. The last decade of the 20th century was the most turbulent Rwanda has ever experienced in its history. The country was ravaged by civil war, genocide, mass migrations, economic crisis, diseases, return of refugees and environmental destruction. Rwandan families were affected by and are still dealing with impacts such as death, disease, disability, poverty, loss of dignity and imprisonment. This paper uses a geographical perspective, more specifically the geography of conflict, to assess the environmental causes and impacts of the genocide in Rwanda, more than a decade after the genocide. Primary data used in this article were obtained from fieldwork undertaken in Cyangugu and Butare Towns, case studies chosen not only because of their particular history before,  during and after the genocide but also because of their heterogeneous population and physical landscapes. Empirical evidence obtained and secondary data sources indicate that the genocide in Rwanda destroyed not only human resources and social and cultural structures but also infrastructure, development facilities and natural resources which had serious negative consequences on the total environment

CMB Lensing Reconstruction in Real Space

We explore the reconstruction of the gravitational lensing field of the cosmic microwave background in real space showing that very little statistical information is lost when estimators of short range on the celestial sphere are used in place of the customary estimators in harmonic space, which are nonlocal and in principle require a simultaneous analysis of the entire sky without any cuts or excisions. Because virtually all the information relevant to lensing reconstruction lies on angular scales close to the resolution scale of the sky map, the gravitational lensing dilatation and shear fields (which unlike the deflection field or lensing potential are directly related to the observations in a local manner) may be reconstructed by means of quadratic combinations involving only very closely separated pixels. Even though harmonic space provides a more natural context for understanding lensing reconstruction theoretically, the real space methods developed here have the virtue of being faster to implement and are likely to prove useful for analyzing realistic maps containing a galactic cut and possibly numerous small excisions to exclude point sources that cannot be reliably subtracted.Comment: 21 pages, 8 figure

Medicinal plants with cholinesterase inhibitory activity: A Review

Alzheimer’s disease (AD), a common neurodegenerative disease, is characterized by low levels in the brain of the neurotransmitter, acetylcholine (ACh). Clinical treatment of this disease is palliative and relies mostly on enhancing cholinergic function by stimulation of cholinergic receptors or prolonging the availability of ACh released into the neuronal synaptic cleft by use of agents which restore or improve the levels of acetylcholine. Inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), enzymes which breakdown acetylcholine, are considered as a promising strategy for the treatment of AD. A potential source of AChE and BChE inhibitors is provided by the abundance of plants in nature, and natural products continue to provide useful drugs and templates for the development of other compounds. The present work constitutes a review of the literature on 123 species of medicinal plants that have been tested for AChE inhibitory activity and 42 plant species which have been tested for BChE inhibitory activity. The plant species listed are potential cholinesterase inhibitors and may aid researchers in their study of natural products which may be useful in the treatment of AD.Key words: Alzheimer’s disease, acetylcholine, acetylcholinesterase, butyrylcholinesterase and medicinal plants