The Function of the Medieval in Jean-Jacques Rousseau's Nouvelle Heloise:A Rereading of the Abelard and Heloise Motif

International audienceJean-Jacques Rousseau's critical rewriting in his of two foundational medieval works—the letters of Abélard and Héloïse, and Petrarch's —reveals the crucial role that the medieval played in his own moral vision. This article both identifies a possible eighteenth-century source for Rousseau's retelling of the Abélard and Héloïse story, and explores the function played by the medieval in his novel. The medieval in , as in his larger thought, was not a chronological, but an ethical category. It spoke not of historical events, but of his own “pays des chimères”. Because of its position outside of the accepted classical canons, it could incarnate an alternative vision commensurate with Rousseau's own self-image as an outsider to the morally corrupted societies of his own time. Associated with the purer language of music, the medieval finally offered access to a higher spiritual plane, exemplified by Julie's role as a Mary-like or even Christ-like figure. As such, the medieval ultimately served as an epistemological counter-model, an imaginary point of origin within a larger history of human virtue

Des catéchismes à Voltaire : le projet MEDIATE et le rôle des livres « moyens » dans la transmission culturelle à l’époque des Lumières

Cet article présente un projet numérique financé par le Conseil européen de la recherche, MEDIATE (Measuring Enlightenment : disseminating ideas, authors, and texts in Europe), dont le but est d’étudier la circulation transnationale des livres à l’époque des Lumières (1665-1830). Prenant appui sur un corpus inédit de quelques centaines de catalogues de vente aux enchères de bibliothèques privées, il suppose que parmi les livres les plus diffusés se trouve une catégorie d’ouvrages popularisateurs constituant un corpus de textes de culture moyenne (middlebrow). En tant que passerelle intellectuelle, ces livres ont permis à un lectorat de sous-élite de faire connaissance avec les nouvelles idées des Lumières, sans pour autant abandonner ses lectures traditionnelles, d’empreinte religieuse. Après avoir décrit les origines du projet, nous examinons les traits typiques de ce corpus pour aboutir à une présentation de la base de données MEDIATE et de son apport à nos recherches

La transmission des savoirs à l’ère numérique

Nouveaux outils, nouveaux usages, nouveaux publics : la révolution technologique a changé la manière de produire, organiser et partager les savoirs. Pour interroger les modalités de cette transmission, l’ouvrage donne la parole à des chercheurs et à des collectionneurs. La diversité de leurs témoignages offre un ensemble original de réflexions et d’orientations méthodologiques qui sont autant d’études de cas dans un contexte de mobilités ergonomiques et participatives. Le Congrès national des sociétés historiques et scientifiques rassemble chaque année universitaires, membres de sociétés savantes et jeunes chercheurs. Ce recueil est issu de travaux présentés lors du 143e Congrès sur le thème « La transmission des savoirs »

Fifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016

Peer reviewe

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

Cuentos del Olivar

En este apasionante viaje tenemos las puertas abiertas para todo aquel que se quiera sumar, ya sea trabajando en pos de la difusión de la cultura ligada al olivo o disfrutando de lecturas como las que se recogen en este libro, que seguro les depara un sabroso disfrute y les descubre una cultura del olivar que tiene a sus espaldas varios milenios de historia. Les deseo que paladeen cada uno de estos relatos, que conforman un excelente aperitivo literario.Área de Historia del Art

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality