175 research outputs found

    Profiles of Adolescent Identity Development: Response to an Intervention for Alcohol/Other Drug Problems

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    The purpose of this study was to examine identity development among adolescents participating in an after-school alcohol/other drug (AOD) abuse intervention program (8 females and 12 males, ages 14–17) to identify how identity development was associated with intervention success. To achieve this goal we (a) garnered information from two identity interviews conducted during the first week of the intervention and 6 to 8 weeks later; (b) adopted a qualitative, person-centered analytical strategy to identify identity profiles; and (c) examined the intervention response of the adolescents, as recorded in intervention documents, in the different identity profile groups. Analyses revealed five identity profiles wherein adolescents differed in their responses to the ‘‘identity challenges’’ encountered in the intervention. Implications for AOD interventions are discussed

    Identity Formation in a Relational Context: A Person-Centered Analysis of Troubled Youth

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    The purpose of this study was to examine the identity formation of troubled youth (8 female and 12 male adolescents, ages 14–17) in an after-school treatment program for problem behavior. To achieve this goal we (a) garnered information from 2 identity interviews given 6 to 8 weeks apart, (b) adopted a qualitative, person-centered analytical strategy to identify identity profiles, and (c) examined the identity profiles within a relational context, focusing on the developmentally salient domains of parents and peers. Analyses revealed 5 identity profiles similar to the identity statuses previously described by Marcia and others, but with unique phenomenological differences. Across the profiles, youth differed in their responses (in terms of exploration and commitment) to the “identity challenges” they encountered during this brief period. Likewise, the relational contexts of parental and peer support also varied across profiles

    Why Haven\u27t You Published That Research (and Your Other Ideas)?

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    Various disincentives and barriers keep communicators from pursuing scholarly publication opportunities

    Dechlorination of 2,3,5,6-tetrachlorobiphenyl by a phototrophic enrichment culture

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    A phototrophic enrichment culture, using acetate as carbon source, reductively dechlorinated 2,3,5,6-tetrachlorobiphenyl. ortho chlorines were removed preferentially over meta chlorines. Tri- and dichlorobiphenyls were the major products. During 14 months incubation, chlorine was removed from 58% of the target molecules; 19% of the total chlorines were removed. Dechlorination did not occur in a control culture incubated in the dark.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29945/1/0000303.pd

    A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene

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    BACKGROUND: Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses. The assay is based on the use of degenerate PCR to target a gene common to these viruses, the DNA polymerase, and sequencing the products. RESULTS: We evaluated our method by applying it to fowl adenovirus isolates, catfish herpesvirus isolates, and largemouth bass ranavirus (iridovirus) from cell culture and lymphocystis disease virus (iridovirus) and avian poxvirus from tissue. All viruses with the exception of avian poxvirus produced the expected product. After optimization of extraction procedures, and after designing and applying an additional primer we were able to produce polymerase gene product from the avian poxvirus genome. The sequence data that we obtained demonstrated the simplicity and potential of the method for routine use in characterizing large DNA viruses. The adenovirus samples were demonstrated to represent 2 types of fowl adenovirus, fowl adenovirus 1 and an uncharacterized avian adenovirus most similar to fowl adenovirus 9. The herpesvirus isolate from blue catfish was shown to be similar to channel catfish virus (Ictalurid herpesvirus 1). The case isolate of largemouth bass ranavirus was shown to exactly match the type specimen and both were similar to tiger frog virus and frog virus 3. The lymphocystis disease virus isolate from largemouth bass was shown to be related but distinct from the two previously characterized lymphocystis disease virus isolates suggesting that it may represent a distinct lymphocystis disease virus species. CONCLUSION: The method developed is rapid and broadly applicable to cell culture isolates and infected tissues. Targeting a specific gene for in the large DNA viruses and adenoviruses provide a common reference for grouping the newly identified viruses according to relatedness to sequences of reference viruses and the submission of the sequence data to GenBank will build the database to make the BLAST analysis a valuable resource readily accessible by most diagnostic laboratories. We demonstrated the utility of this assay on viruses that infect fish and birds. These hosts are phylogenetically distant from mammals yet, sequence data suggests that the assay would work equally as well on mammalian counterparts of these groups of viruses. Furthermore, we demonstrated that obtaining genetic information on routine diagnostic samples has great potential for revealing new virus strains and suggesting the presence of new species

    Gee, But I\u27d Like to Make You Happy

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    Illustration of women in various styles of clothes.https://scholarsjunction.msstate.edu/cht-sheet-music/2899/thumbnail.jp

    Cost Analysis in a Multi-Mission Operations Environment

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    Spacecraft control centers have evolved from dedicated, single-mission or single mission-type support to multi-mission, service-oriented support for operating a variety of mission types. At the same time, available money for projects is shrinking and competition for new missions is increasing. These factors drive the need for an accurate and flexible model to support estimating service costs for new or extended missions; the cost model in turn drives the need for an accurate and efficient approach to service cost analysis. The National Aeronautics and Space Administration (NASA) Huntsville Operations Support Center (HOSC) at Marshall Space Flight Center (MSFC) provides operations services to a variety of customers around the world. HOSC customers range from launch vehicle test flights; to International Space Station (ISS) payloads; to small, short duration missions; and has included long duration flagship missions. The HOSC recently completed a detailed analysis of service costs as part of the development of a complete service cost model. The cost analysis process required the team to address a number of issues. One of the primary issues involves the difficulty of reverse engineering individual mission costs in a highly efficient multi-mission environment, along with a related issue of the value of detailed metrics or data to the cost model versus the cost of obtaining accurate data. Another concern is the difficulty of balancing costs between missions of different types and size and extrapolating costs to different mission types. The cost analysis also had to address issues relating to providing shared, cloud-like services in a government environment, and then assigning an uncertainty or risk factor to cost estimates that are based on current technology, but will be executed using future technology. Finally the cost analysis needed to consider how to validate the resulting cost models taking into account the non-homogeneous nature of the available cost data and the decreasing flight rate. This paper presents the issues encountered during the HOSC cost analysis process, and the associated lessons learned. These lessons can be used when planning for a new multi-mission operations center or in the transformation from a dedicated control center to multi-center operations, as an aid in defining processes that support future cost analysis and estimation. The lessons can also be used by mature service-oriented, multi-mission control centers to streamline or refine their cost analysis process

    Predictive coupled-cluster isomer orderings for some Sin{}_nCm{}_m (m,n12m, n\le 12) clusters; A pragmatic comparison between DFT and complete basis limit coupled-cluster benchmarks

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    The accurate determination of the preferred Si12C12{\rm Si}_{12}{\rm C}_{12} isomer is important to guide experimental efforts directed towards synthesizing SiC nano-wires and related polymer structures which are anticipated to be highly efficient exciton materials for opto-electronic devices. In order to definitively identify preferred isomeric structures for silicon carbon nano-clusters, highly accurate geometries, energies and harmonic zero point energies have been computed using coupled-cluster theory with systematic extrapolation to the complete basis limit for set of silicon carbon clusters ranging in size from SiC3_3 to Si12C12{\rm Si}_{12}{\rm C}_{12}. It is found that post-MBPT(2) correlation energy plays a significant role in obtaining converged relative isomer energies, suggesting that predictions using low rung density functional methods will not have adequate accuracy. Utilizing the best composite coupled-cluster energy that is still computationally feasible, entailing a 3-4 SCF and CCSD extrapolation with triple-ζ\zeta (T) correlation, the {\it closo} Si12C12{\rm Si}_{12}{\rm C}_{12} isomer is identified to be the preferred isomer in support of previous calculations [J. Chem. Phys. 2015, 142, 034303]. Additionally we have investigated more pragmatic approaches to obtaining accurate silicon carbide isomer energies, including the use of frozen natural orbital coupled-cluster theory and several rungs of standard and double-hybrid density functional theory. Frozen natural orbitals as a way to compute post MBPT(2) correlation energy is found to be an excellent balance between efficiency and accuracy

    Irregular behaviour of class numbers and Euler-Kronecker constants of cyclotomic fields: the log log log devil at play

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    Kummer (1851) and, many years later, Ihara (2005) both posed conjectures on invariants related to the cyclotomic field Q(ζq)\mathbb Q(\zeta_q) with qq a prime. Kummer's conjecture concerns the asymptotic behaviour of the first factor of the class number of Q(ζq)\mathbb Q(\zeta_q) and Ihara's the positivity of the Euler-Kronecker constant of Q(ζq)\mathbb Q(\zeta_q) (the ratio of the constant and the residue of the Laurent series of the Dedekind zeta function ζQ(ζq)(s)\zeta_{\mathbb Q(\zeta_q)}(s) at s=1s=1). If certain standard conjectures in analytic number theory hold true, then one can show that both conjectures are true for a set of primes of natural density 1, but false in general. Responsible for this are irregularities in the distribution of the primes. With this survey we hope to convince the reader that the apparently dissimilar mathematical objects studied by Kummer and Ihara actually display a very similar behaviour.Comment: 20 pages, 1 figure, survey, to appear in `Irregularities in the Distribution of Prime Numbers - Research Inspired by Maier's Matrix Method', Eds. J. Pintz and M. Th. Rassia
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