What\u27s Law Got to Do with It?: An Overview of CEDAW\u27s Treatment of Violence Against Women and Girls Through Case Studies

Article published in the Michigan State Law Review

What's Law Got to Do with It?: An Overview of CEDAW's Treatment of Violence Against Women and Girls Through Case Studies

Article published in the Michigan State Law Review

Abrasivity of Yttria Tetragonal Zirconia Polycrystal (Y-TZP) to dental enamel in comparison to noble white high palladium alloy

Objectives: To test the wear of enamel against Yttria Tetragonal Zirconia Polycrystals (Y-TZP) in comparison to the wear of enamel against a noble white high Palladium alloy. Methods: A total of 20 specimens were used, 10 of Y-TZP and 10 of High Palladium alloy, both were subjected to 202,800 contacts against an enamel rod 2x2 mm in cross section under a mean load of 475.04g leading to a mean force of 4.66 N in a Wilson Wear Machine. The specimens were kept in Dulbecco’s phosphate buffered saline at a pH of 7 and the enamel rods were measured before and after the experiment for loss of enamel height (mm). Results The mean wear caused by the Y-TZP and the High Palladium alloy tested was 0.0912 mm, and 0.0113 mm respectively. This difference was statistically significant (p = 0.012 (p<0.05)). Significance It is recommended that Y-TZP is not to be used to form the occlusal surfaces of indirect restorations due to its high abrasive potential with respect to dental enamel

The Forum: Spring 2004

Spring 2004 journal of the Honors Program at the University of North Dakota. The issue includes stories, poems, essays and art by undergraduate students.https://commons.und.edu/und-books/1054/thumbnail.jp

The Forum: Fall 2003

Fall 2003 journal of the Honors Program at the University of North Dakota. The issue includes stories, poems, essays and art by undergraduate students.https://commons.und.edu/und-books/1052/thumbnail.jp

The Forum: Winter 2004

Winter 2004 journal of the Honors Program at the University of North Dakota. The issue includes stories, poems, essays and art by undergraduate students.https://commons.und.edu/und-books/1055/thumbnail.jp

Sphingolipid synthesis inhibition by myriocin administration enhances lipid consumption and ameliorates lipid response to myocardial ischemia reperfusion injury

Myocardial infarct requires prompt thrombolytic therapy or primary percutaneous coronary intervention to limit the extent of necrosis, but reperfusion creates additional damage. Along with reperfusion, a maladaptive remodeling phase might occur and it is often associated with inflammation, oxidative stress, as well as a reduced ability to recover metabolism homeostasis. Infarcted individuals can exhibit reduced lipid turnover and their accumulation in cardiomyocytes, which is linked to a deregulation of peroxisome proliferator activated receptors (PPARs), controlling fatty acids metabolism, energy production, and the anti-inflammatory response. We previously demonstrated that Myriocin can be effectively used as post-conditioning therapeutic to limit ischemia/reperfusion-induced inflammation, oxidative stress, and infarct size, in a murine model. In this follow-up study, we demonstrate that Myriocin has a critical regulatory role in cardiac remodeling and energy production, by up-regulating the transcriptional factor EB, PPARs nuclear receptors and genes involved in fatty acids metabolism, such as VLDL receptor, Fatp1, CD36, Fabp3, Cpts, and mitochondrial FA dehydrogenases. The overall effects are represented by an increased \u3b2-oxidation, together with an improved electron transport chain and energy production. The potent immunomodulatory and metabolism regulatory effects of Myriocin elicit the molecule as a promising pharmacological tool for post-conditioning therapy of myocardial ischemia/reperfusion injury