Source extraction and photometry for the far-infrared and sub-millimeter continuum in the presence of complex backgrounds

(Abridged) We present a new method for detecting and measuring compact sources in conditions of intense, and highly variable, fore/background. While all most commonly used packages carry out the source detection over the signal image, our proposed method builds from the measured image a "curvature" image by double-differentiation in four different directions. In this way point-like as well as resolved, yet relatively compact, objects are easily revealed while the slower varying fore/background is greatly diminished. Candidate sources are then identified by looking for pixels where the curvature exceeds, in absolute terms, a given threshold; the methodology easily allows us to pinpoint breakpoints in the source brightness profile and then derive reliable guesses for the sources extent. Identified peaks are fit with 2D elliptical Gaussians plus an underlying planar inclined plateau, with mild constraints on size and orientation. Mutually contaminating sources are fit with multiple Gaussians simultaneously using flexible constraints. We ran our method on simulated large-scale fields with 1000 sources of different peak flux overlaid on a realistic realization of diffuse background. We find detection rates in excess of 90% for sources with peak fluxes above the 3-sigma signal noise limit; for about 80% of the sources the recovered peak fluxes are within 30% of their input values.Comment: Accepted on A&

Bias-dependent Contact Resistance in Rubrene Single-Crystal Field-Effect Transistors

We report a systematic study of the bias-dependent contact resistance in rubrene single-crystal field-effect transistors with Ni, Co, Cu, Au, and Pt electrodes. We show that the reproducibility in the values of contact resistance strongly depends on the metal, ranging from a factor of two for Ni to more than three orders of magnitude for Au. Surprisingly, FETs with Ni, Co, and Cu contacts exhibits an unexpected reproducibility of the bias-dependent differential conductance of the contacts, once this has been normalized to the value measured at zero bias. This reproducibility may enable the study of microscopic carrier injection processes into organic semiconductors.Comment: 4 pages, 4 figure

Methods for preclinical validation of software as a medical device

Software as a medical device is subject to dedicated regulatory requirements before it can be used on human beings. The certification process in Europe requires that sufficient data on clinical benefits are available before the device is CE marked. This position paper describes our proposal of a risk-based approach to technical and preclinical validation of software as medical devices. This approach ensures that all technical solutions for safety are implemented in the software and that all information for safe use is consistent before the software can be made available to patients. This approach is compliant to the main international standards ISO 13485 on quality systems and ISO 14971 on risk management and therefore ensures regulatory compliance as well as patient protection. This integrated approach allows the designers of the software to integrate regulatory and safety testing in the technical testing of the candidate release version of the device. This approach ensures patient safety and regulatory compliance at the same time as technical functionality

Direct Estimate of Cirrus Noise in Herschel Hi-GAL Images

In Herschel images of the Galactic plane and many star forming regions, a major factor limiting our ability to extract faint compact sources is cirrus confusion noise, operationally defined as the "statistical error to be expected in photometric measurements due to confusion in a background of fluctuating surface brightness". The histogram of the flux densities of extracted sources shows a distinctive faint-end cutoff below which the catalog suffers from incompleteness and the flux densities become unreliable. This empirical cutoff should be closely related to the estimated cirrus noise and we show that this is the case. We compute the cirrus noise directly, both on Herschel images from which the bright sources have been removed and on simulated images of cirrus with statistically similar fluctuations. We connect these direct estimates with those from power spectrum analysis, which has been used extensively to predict the cirrus noise and provides insight into how it depends on various statistical properties and photometric operational parameters. We report multi-wavelength power spectra of diffuse Galactic dust emission from Hi-GAL observations at 70 to 500 microns within Galactic plane fields at l= 30 degrees and l= 59 degrees. We find that the exponent of the power spectrum is about -3. At 250 microns, the amplitude of the power spectrum increases roughly as the square of the median brightness of the map and so the expected cirrus noise scales linearly with the median brightness. Generally, the confusion noise will be a worse problem at longer wavelengths, because of the combination of lower angular resolution and the rising power spectrum of cirrus toward lower spatial frequencies, but the photometric signal to noise will also depend on the relative spectral energy distribution of the source compared to the cirrus.Comment: 4 pages (in journal), 3 figures, Astronomy and Astrophysics, accepted for publication 13 May 201

Heavy flavours in AA collisions: production, transport and final spectra

A multi-step setup for heavy-flavour studies in high-energy nucleus-nucleus (AA) collisions --- addressing within a comprehensive framework the initial Q-Qbar production, the propagation in the hot medium until decoupling and the final hadronization and decays --- is presented. The initial hard production of Q-Qbar pairs is simulated using the POWHEG pQCD event generator, interfaced with the PYTHIA parton shower. Outcomes of the calculations are compared to experimental data in pp collisions and are used as a validated benchmark for the study of medium effects. In the AA case, the propagation of the heavy quarks in the medium is described in a framework provided by the relativistic Langevin equation. For the latter, different choices of transport coefficients are explored (either provided by a perturbative calculation or extracted from lattice-QCD simulations) and the corresponding numerical results are compared to experimental data from RHIC and the LHC. In particular, outcomes for the nuclear modification factor R_AA and for the elliptic flow v_2 of D/B mesons, heavy-flavour electrons and non-prompt J/\psi's are displayed.Comment: 16 pages, 21 figure

First principle theory of correlated transport through nano-junctions

We report the inclusion of electron-electron correlation in the calculation of transport properties within an ab initio scheme. A key step is the reformulation of Landauer's approach in terms of an effective transmittance for the interacting electron system. We apply this framework to analyze the effect of short range interactions on Pt atomic wires and discuss the coherent and incoherent correction to the mean-field approach.Comment: 5 pages, 3 figure