Future Projections of Urban Waste Flows aand their Impacts in African Metropolises Cities

This paper presents future trends of urban wastes and their impacts on the environment of African cities using plausible mitigation scenarios. To accomplish this, an integrated dynamic model for urban waste flows was developed, tested, calibrated and validated. Its parameter sensitivity was analyzed. Using population projection up to 2052 with different levels of technological implementation, policy enforcement and awareness raising, four runs were executed. The “business as usual” run showed that with no additional mitigation measures, the environmental quality in Kampala and Dar es salaam Cities deteriorates. The “more enforcement” and “more collection” scenarios showed good reduction in environmental loads but they perform less well in resource recovery. The “proper management” scenario that combines enhanced technological implementation, awareness raising and policy enforcement, produced the smallest environmental loads, and recovered the largest amount of resources. Thus, the city authorities, general public, community based organisations and Non-governmental organizations would have to increase their efforts in finances and commitment to improve the urban environmental quality and increase resource recovery

Magnetic monopole and string excitations in a two-dimensional spin ice

We study the magnetic excitations of a square lattice spin-ice recently produced in an artificial form, as an array of nanoscale magnets. Our analysis, based upon the dipolar interaction between the nanomagnetic islands, correctly reproduces the ground-state observed experimentally. In addition, we find magnetic monopole-like excitations effectively interacting by means of the usual Coulombic plus a linear confining potential, the latter being related to a string-like excitation binding the monopoles pairs, what indicates that the fractionalization of magnetic dipoles may not be so easy in two dimensions. These findings contrast this material with the three-dimensional analogue, where such monopoles experience only the Coulombic interaction. We discuss, however, two entropic effects that affect the monopole interactions: firstly, the string configurational entropy may loose the string tension and then, free magnetic monopoles should also be found in lower dimensional spin ices; secondly, in contrast to the string configurational entropy, an entropically driven Coulomb force, which increases with temperature, has the opposite effect of confining the magnetic defects.Comment: 8 pages. Accepted by Journal of Applied Physics (2009

Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra)

The roots of licorice (Glycyrrhiza glabra) are a rich source of flavonoids, in particular, prenylated flavonoids, such as the isoflavan glabridin and the isoflavene glabrene. Fractionation of an ethyl acetate extract from licorice root by centrifugal partitioning chromatography yielded 51 fractions, which were characterized by liquid chromatography–mass spectrometry and screened for activity in yeast estrogen bioassays. One third of the fractions displayed estrogenic activity towards either one or both estrogen receptors (ERs; ERa and ERß). Glabrene-rich fractions displayed an estrogenic response, predominantly to the ERa. Surprisingly, glabridin did not exert agonistic activity to both ER subtypes. Several fractions displayed higher responses than the maximum response obtained with the reference compound, the natural hormone 17ß-estradiol (E2). The estrogenic activities of all fractions, including this so-called superinduction, were clearly ER-mediated, as the estrogenic response was inhibited by 20–60% by known ER antagonists, and no activity was found in yeast cells that did not express the ERa or ERß subtype. Prolonged exposure of the yeast to the estrogenic fractions that showed superinduction did, contrary to E2, not result in a decrease of the fluorescent response. Therefore, the superinduction was most likely the result of stabilization of the ER, yeast-enhanced green fluorescent protein, or a combination of both. Most fractions displaying superinduction were rich in flavonoids with single prenylation. Glabridin displayed ERa-selective antagonism, similar to the ERa-selective antagonist RU 58668. Whereas glabridin was able to reduce the estrogenic response of E2 by approximately 80% at 6¿×¿10-6 M, glabrene-rich fractions only exhibited agonistic responses, preferentially on ERa

Application of Fuzzy Logic in Automated Cow Status Monitoring

Sensors that measure yield, temperature, electrical conductivity of milk, and animal activity can be used for automated cow status monitoring. The occurrence of false-positive alerts, generated by a detection model, creates problems in practice. We used fuzzy logic to classify mastitis and estrus alerts; our objective was to reduce the number of false-positive alerts and not to change the level of detected cases of mastitis and estrus. Inputs for the fuzzy logic model were alerts from the detection model and additional information, such as the reproductive status. The output was a classification, true or false, of each alert. Only alerts that were classified true should be presented to the herd manager. Additional information was used to check whether deviating sensor measurements were caused by mastitis or estrus, or by other influences. A fuzzy logic model for the classification of mastitis alerts was tested on a data set from cows milked in an automatic milking system. All clinical cases without measurement errors were classified correctly. The number of false-positive alerts over time from a subset of 25 cows was reduced from 1266 to 64 by applying the fuzzy logic model. A fuzzy logic model for the classification of estrus alerts was tested on two data sets. The number of detected cases decreased slightly after classification, and the number of false-positive alerts decreased considerably. Classification by a fuzzy logic model proved to be very useful in increasing the applicability of automated cow status monitoring

High-amplitude lake-level changes in tectonically active Lake Issyk-Kul (Kyrgyzstan) revealed by high-resolution seismic reflection data

A total of 84 seismic profiles, mainly from the western and eastern deltas of Lake Issyk-Kul, were used to identify lake-level changes. Seven stratigraphic sequences were reconstructed, each containing a series of delta lobes that were formed during former lake-level stillstands or during slow lake-level increase or decrease. The lake level has experienced at least four cycles of stepwise rise and fall of 400 m or more. These fluctuations were mainly caused by past changes in the atmospheric circulation pattern. During periods of low lake levels, the Siberian High was likely to be strong, bringing dry air masses from the Mongolian steppe blocking the midlatitude Westerlies. During periods of high lake levels, the Siberian High must have been weaker or displaced, and the midlatitude Westerlies could bring moister air masses from the Mediterranean and North Atlantic regions

Cost-effectiveness of ovarian stimulation agents for IUI in couples with unexplained subfertility

Acknowledgements The authors wish to thank M.P. Diamond, R.S. Legro, K. Peeraer, M. Erdem, T. Dankert, and R. Ecochard, on behalf of the IUI IPDMA collaboration, for providing data from their RCTs for the IPDMA of which the results are used in a sensitivity analysis. Funding This work was supported by ZonMw Doelmatigheidsonderzoek, grant 80-85200-98-91072. The funder had no role in the design, conduct or reporting of this work. B.W.M. is supported by a NHMRC Practitioner Fellowship (GNT1082548).Peer reviewedPublisher PD