1,174 research outputs found
Grappling with the miseducation of Montessori: a feminist posthuman re-reading of ‘child’ in early childhood contexts
This paper demonstrates how feminist posthumanism can reconfigure conceptualisations of, and practices with, ‘child’ in Montessori early childhood contexts. It complicates Montessori’s contemporary reputation as a ‘middle-class phenomenon’ by returning to the earliest Montessori schools as a justice-oriented project for working-class children and families. Grappling with the contradictions and inconsistencies of Montessori thought, this paper both acknowledges the legacy of Montessori's feminism, whilst also situating her project within the wider colonial capitalist context in which it emerged. A critical engagement with Montessori education unsettles modernist conceptualisations of ‘child’ and its civilising agenda on minds and bodies. Specifically, Montessori child observation (as a civilising mission) is disrupted and re-read from a feminist posthumanist orientation to generate more relational, queer and expansive accounts of how child is produced through observation. Working with three ‘encounters’ from fieldwork at a Montessori nursery we attend to the material discursive affective manifestation of social class, gender, sexuality and ‘race’ and what that means for child figurations in Montessori contexts. We conclude by embracing Snaza’s ‘bewildering education’, to reach towards different imaginaries of ‘child’ that are not reliant on dialectics of ‘human’ and ‘nonhuman’, and that allows ‘child’ to be taken seriously, without risking erasure of fleshy, leaky, porous, codified bodies in Montessori spaces
Reconfiguring the ‘Male Montessorian’: the mattering of gender through pink towering practices
This paper attempts to open out investigations in ECEC by working beyond anthropocentric accounts of gender. Drawing upon feminist new materialist philosophies we ask whether it might be possible to reconfigure ideas about gender that recognise it as produced through everyday processes and material-affective entanglements. In order to do this, we work with Montessori materials, spaces and practices to grapple with the ways that gender is produced through human-material-semiotic encounters. By focusing on familiar Montessori objects, we follow diffractive lines of enquiry to extend investigations and generate new knowledge about gender in ECEC. This shift in focus allows other accounts about gender to find expression. We argue gender can be encountered as more than an exclusively human matter; and we go on to debate what that might potentiate (i.e. that if gender is fleeting, shifting, and produced within micro-moments there is freedom to break free from narrow framings that fix people, such as ‘the Male Montessorian’, in unhelpful ways). An approach that foregrounds affect and materiality makes a hopeful, generative and expansive contribution to the field
Two-parameter uniformly elliptic Sturm–Liouville problems with eigenparameter-dependent boundary conditions
We consider the two-parameter Sturm–Liouville system –y "1+q1y1=(λr11+μr12)y1 [0,1], with the boundary conditions y'1(0)/y1(0)=cotΑ1 and y'1(1)/y1(1)=a1λ+b1/c1λ+d1 and –y" 2+q2y2=(λr21+μr22)y2 on [0,1] with the boundary conditions y'2(0)/y2(0)=cotΑ2 and y'2(1)/y2(1)=a2μ+b2/c2μ+d2 subject to the uniform-left-definite and uniform-ellipticity conditions; where and qi and rij are continuous real valued functions on [0,1], the angle Αi is in [0, π) and ai, bi, ci, di, and are real numbers with δ i = aidi - bici > 0 and ci ≠0 for i,j = 1,2. Results are given on asymptotics, oscillation of eigenfunctions and location of eigenvalues
The erythroblastic island as an emerging paradigm in the anemia of inflammation
Terminal erythroid differentiation occurs in the bone marrow, within specialized niches termed erythroblastic islands. These functional units consist of a macrophage surrounded by differentiating erythroblasts and have been described more than five decades ago, but their function in the pathophysiology of erythropoiesis has remained unclear until recently. Here we propose that the central macrophage in the erythroblastic island contributes to the pathophysiology of anemia of inflammation. After introducing erythropoiesis and the interactions between the erythroblasts and the central macrophage within the erythroblastic islands, we will discuss the immunophenotypic characterization of this specific subpopulation of macrophages. We will then integrate these concepts into the currently known pathophysiological drivers of anemia of inflammation and address the role of the central macrophage in this disorder. Finally, as a means of furthering our understanding of the various concepts, we will discuss the differences between murine and rat models with regard to developmental and stress erythropoiesis in an attempt to define a model system representative of human pathophysiology
Application of Regression and Fuzzy Logic Method for Prediction of Tool Life
AbstractThis paper presents a model for predicting tool life when end milling IS2062 steel using P30 uncoated carbide tipped tool under various cutting conditions. A tool life model is developed from regression model obtained by using results of the experiments conducted based on Taguchi's approach. A second model is developed based on fuzzy logic method for predicting tool life. The results obtained from fuzzy method are compared with regression model. The results of the fuzzy model is found to be more closer to experimental value
Comparative Analysis of Regression Models for Remote Sensing-based Water Quality Assessment
The 80-kilometer-long Vembanad Lake in Kerala, India, is a Ramsar site. Eutrophication is deteriorating its water quality and threatening its biodiversity. In this study, satellite imageries of Sentinel 2A and Landsat 8 OLI were utilized to determine its water quality. Various data sets of the water quality parameters viz. pH, Electrical conductivity, TSS, TDS, BOD, DO, chloride etc. are analyzed and interpreted. Regression models were developed on the parameters taken up for water quality analysis. The empirical R2 values of the developed models evidenced the accuracy of the developed mdoels. The findings show that remote sensing images are reliable for analyzing surface water quality characteristics. The comparative analysis of the model developed illustrated the effectiveness of using the imaging systems mentioned above for water quality index estimation through remote sensing
Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes
Purified preparations of scrapie prions contain one major macromolecule, designated prion protein (PrP). Genes encoding PrP are found in normal animals and humans but not within the infectious particles. The PrP gene was assigned to human chromosome 20 and the corresponding mouse chromosome 2 using somatic cell hybrids. In situ hybridization studies mapped the human PrP gene to band 20p12→pter. Our results should lead to studies of genetic loci syntenic with the PrP gene, which may play a role in the pathogenesis of prion diseases or other degenerative neurologic disorders
Reconstruction of the insulin-like signalling pathway of Haemonchus contortus
Background: In the present study, we reconstructed the insulin/insulin-like growth factor 1 signalling (IIS) pathway for Haemonchus contortus, which is one of the most important eukaryotic pathogens of livestock worldwide and is related to the free-living nematode Caenorhabditis elegans.
Methods: We curated full-length open-reading frames from assembled transcripts, defined the complement of genes that encode proteins involved in this pathway and then investigated the transcription profiles of these genes for all key developmental stages of H. contortus.
Results: The core components of the IIS pathway are similar to their respective homologs in C. elegans. However, there is considerable variation in the numbers of isoforms between H. contortus and C. elegans and an absence of AKT-2 and DDL-2 homologs from H. contortus. Interestingly, DAF-16 has a single isoform in H. contortus compared with 12 in C. elegans, suggesting novel functional roles in the parasitic nematode. Some IIS proteins, such as DAF-18 and SGK-1, vary in their functional domains, indicating distinct roles from their homologs in C. elegans.
Conclusions: This study paves the way for the further characterization of key signalling pathways in other socioeconomically important parasites and should help understand the complex mechanisms involved in developmental processes
- …