6 research outputs found
Correction to: Expansion of acquired 16S rRNA methytransferases along with CTX-M-15, NDM and OXA-48 within three sequence types of Escherichia coli from northeast India
Teratomas in central nervous system: A clinico-morphological study with review of literature
Background: Cranio-spinal axis teratomas are rare. This subset is
interesting because symptoms can be varied, depending on the location.
Histopathology is diagnostic; most of the lesions are benign. Rarely,
malignancy develops in any of the somatic components. Aims: To study
the demographic, clinico-morphological and follow-up data of central
nervous system (CNS) teratomas. Materials and Methods: Cases diagnosed
as mature or immature teratomas in the CNS over a 20-year period were
included in the study. Clinico-radiological, demographic and follow-up
data of these cases were analyzed. Results: A total of 14 tumors were
diagnosed as teratomas. Of these, 11 were mature cystic teratomas; and
1 case each, of teratoma with malignant transformation,
terato-carcinoma and mixed germ cell tumor (immature teratoma with
germinoma). Six of the 14 cases were intracranial and 8 were spinal.
Presenting features varied according to the location. Radiologically,
contrast enhancement with predominantly solid component was suggestive
of malignancy or an aggressive tumor. Morphologically, a variety of
tissue derivatives were seen in the cases. Excision was curative or
provided symptomatic relief in most cases; terato-carcinoma and mixed
germ cell tumor patients needed adjuvant radiotherapy. Conclusion: CNS
teratomas are rare. Morphology and location decide outcome