Dimethyl 4-eth­oxy-1-(4-methyl-2-pyri­dyl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3-dicarboxyl­ate

In the title compound, C16H18N2O6, the dihedral angle between the aromatic ring planes is 8.11 (6)°. One of the O atoms is disordered over two sites of equal occupancy. In the crystal structure, aromatic π–π stacking [centroid-to-centroid separation = 3.5503 (8) Å] helps to consolidate the packing

Isoquinoline-catalyzed reaction between 4-hydroxycoumarin or 4-hydroxy-6-methylpyran-1-one and dialkyl acetylene dicarboxylates: synthesis of coumarin and pyranopyrane derivatives

In this work we report the reaction between dialkyl acetylenedicarboxylates and enolic systems such as 5,5-dimethyl-1,3-cyclohexanedione, 1,3-cyclohexanedione, 4-hydroxycoumarin or 4-hydroxy-6-methylpyran-1-one in the presence of isoquinoline, which leads to new coumarin and pyranopyran derivatives

Four -Component Reaction Between Cyanoacetamide, Aryl Aldehydes and Ethyl Acetoacetate with Ammonium Acetate

Abstract: A new and efficient one-pot synthesis of dihydropyridones derivatives by fourcomponent reaction between cyanoacetamide, aryl aldehydes and ethyl acetoacetate with ammonium acetate using pyridine is described. The reaction was performed in ethanol under reflux conditions and afforded good yields of products

Simple synthesis of enaminones derived from pyridine, acetylenic compounds and cyclohexane-1,3-diones

996-999The reactive 1:1 intermediate produced in the reaction between pyridine and electron-deficient aeetylenic compounds has been trapped by cyclohexane-1,3-dione or 5,5-dimethylcyclohexane- 1 ,3-dione (dimedone) to yield the stable pyridine-derived enaminones

An efficient synthesis of 4,5-disubstituted 1,2,3-triazoles by three-component reaction between sodium azide, ethyl cyanoacetate or malonitrile and arylglyoxals

Three-component reaction between sodium azide, ethyl cyanoacetate or malonitrile and arylglyoxals afforded 4,5-disubstituted 1,2,3-triazole derivatives in high yields. All reactions were conducted in ethanol as an environmentally benign solvent at room temperature without using any catalyst or modifier. Stable solid products were easily isolated and purified by washing with water and diethyl ether. The structures of the compounds were proved by 1H and 13C NMR and IR spectral and elemental analysis data.</p

ZnO Nanoparticles: An Efficient Reagent, Simple and One-Pot Procedure for Synthesis of Highly Functionalized Dihydropyridine Derivatives

A new and efficient one-pot synthesis of dihydropyridones derivatives by four-component reaction between cyanoacetamide, aryl aldehydes, and ethyl acetoacetate with ammonium acetate using nano ZnO is described. The reaction was performed in ethanol under reflux conditions and afforded good yields of products