Orthoses for Spinal Cord Injury Patients

There are some limitations for patients with spinal cord injury (SCI) when walking with assistive devices. Heavy energy expenditure and walking high loads on the upper limb joints are two main reasons of high rejection rate of orthosis by these patients . Many devices have been designed to enable people with paraplegia to ambulate in an upright position as a solution of these limitations such as mechanical orthoses, hybrid orthoses and powered orthoses. All these devices are designed to solve the problem of standing and walking, but there are some other important notes, which should be considered. For example, the size and weight of external orthoses, donning and doffing, cumbersomeness and independency for using are very important

The mediating effect of supply chain integration on the relationship between information technology, trust and firm performance: a conceptual framework

Supply chain Management has played a significant role in corporate efficiency and has attracted the attention of numerous academicians over the last few years. As the concept of becomes more widely accepted, supply chain integration (SCI) is gaining more attention among both practitioners and academics. The paper aims at understanding how SCI and its antecedents, impacts firm performance. For the literature review of the related academic articles for the previous studies has been taken by international journals in Logistics, Supply Chain Management and Operations Management. The study looked at some variables such as trust and information technology (IT) that might impact the SCI and finally improve firm performance. Therefore, it is crucial for managers to apply their firms IT and trust as lower-order organizational capabilities to improve SCI as a higher-order organizational capability. To aid the study, Resourced-Based View (RBV) theory has been developed as the framework for the present research. The paper also proposes the framework for future research in empirical investigation in manufacturing. This study bridges the gap by developing a framework for measuring SCI, which enables any organization to identify critical success factors for integrating their SC, measures the degree of integration qualitatively and quantitatively and suggest improvement measures

A systematic review of variables used to assess clinically acceptable alignment of unilateral transtibial amputees in the literature.

Prosthetic alignment is a subjective concept which lacks reliability. The outcome responsiveness to prosthetic alignment quality could help to improve subjective and instrument assisted prosthetic alignment. This study was aimed to review variables used to assess clinically acceptable alignment in the literature. The search was done in some databases including: Google Scholar, PubMed, EBSCO, EMBASE, ISI Web of Knowledge and Scopus. The first selection criterion was based on abstracts and titles to address the research questions of interest. The American Academy of Orthotics and Prosthetics checklists were used for paper risk of bias assessment. A total of 25 studies were included in this study. Twenty-four studies revealed the critics of standing position or walking to locate clinically acceptable alignment, only one study measured outcomes in both situations. A total of 253 adults with transtibial amputations and mean age of 48.71 years participated in included studies. The confidence level of included studies was low to moderate, and before-after trial was the most common study design (n = 19). The joint angle, load line location with respect to joints and center of pressure-related parameters were reported as sensitive outcomes to prosthetic alignment quality in standing posture. The amount of forces at various parts of gait cycle and time of events were sensitive to prosthetic alignment quality during walking. Standing balance and posture and temporal parameters of walking could help to locate clinically acceptable alignment.N/

Oxford-MEST classification in IgA nephropathy patients: A report from Iran.

BACKGROUND There is a limited knowledge about the morphological features of IgA nephropathy (IgAN)in the middle east region. OBJECTIVES The objective of this study was to evaluate the spectrum of histopathological findings in IgAN patients at our laboratory. PATIENTS AND METHODS At this work, an observational study reported which was conducted on IgAN patients using the Oxford-MEST classification system. RESULTS In this survey, of 102 patients 71.6 % were male. The mean age of the patients was 37.7 ± 13.6 years. Morphologic variables of MEST classification was as follows; M1: 90.2 %, E: 32 %, S: 67 % also,T in grads I and II were in 30% and 19% respectively, while 51% were in grade zero. A significant difference was observed in segmental glomerulosclerosis (P=0.003) and interstitial fibrosis/tubular atrophy frequency distribution (P= 0.045), between males and females . Furthermore, it was found that mesangial hypercellularity was more prevalent in yonger patients. Moreover, there was a significant correlation between serum creatinine and crescents (P<0.001). There was also significant correlation of serum creatinine with segmental glomerulosclerosis (P<0.001). CONCLUSIONS Higher prevalence of segmental glomerulosclerosis and interstitial fibrosis/ tubular atrophy, as the two of, four variables of Oxford-MEST classification of IgAN in male patients further attests that male gender is a risk factor in this disease.In this study the significant correlation between serum creatinine and crescent was in an agreement with previous studies and suggests for the probable accomodation of extracapillary proliferation as a new variable in MEST system

Co-transplantation of Human Embryonic Stem Cell-derived Neural Progenitors and Schwann Cells in a Rat Spinal Cord Contusion Injury Model Elicits a Distinct Neurogenesis and Functional Recovery

Co-transplantation of neural progenitors (NPs) with Schwann cells (SCs) might be a way to overcome low rate of neuronal differentiation of NPs following transplantation in spinal cord injury (SCI) and the improvement of locomotor recovery. In this study, we initially generated NPs from human embryonic stem cells (hESCs) and investigated their potential for neuronal differentiation and functional recovery when co-cultured with SCs in vitro and co-transplanted in a rat acute model of contused SCI. Co-cultivation results revealed that the presence of SCs provided a consistent status for hESC-NPs and recharged their neural differentiation toward a predominantly neuronal fate. Following transplantation, a significant functional recovery was observed in all engrafted groups (NPs, SCs, NPs+SCs) relative to the vehicle and control groups. We also observed that animals receiving co-transplants established a better state as assessed with the BBB functional test. Immunohistofluorescence evaluation five weeks after transplantation showed invigorated neuronal differentiation and limited proliferation in the co-transplanted group when compared to the individual hESC-NPs grafted group. These findings have demonstrated that the co-transplantation of SCs with hESC-NPs could offer a synergistic effect, promoting neuronal differentiation and functional recovery

Fintech dalam Keuangan Islam: Teori dan Praktik

Book Chapter terkait fintech, namun untuk memberikan distingsi dengan kajian terdahulu, serta agar tidak terjadi reduplikasi pembahasan, diskursus fintech di sini akan ditinjau dari perspektif keuangan Islam yang holistik yang tersebar dalam 18 (delapan belas) pembahasan

Evaluation of Physical and Chemical Quality of Groundwater in Northern Cities of Golestan Province (Bandar Torkaman, Kordkoy, Bandar-e Gaz) in 2005-2010

Introduction and Aims Access to safe water in terms of physical, chemical and microbial parameters is one of the health care providers of community. Testing and analyzing are essential to understand the safety of potable water. The purpose of this study is investigating the chemical and physical quality of drinking water resources in cites of Bandar Torkaman, Bandar Gaz and Kordkoy. Material and Methods In this descriptive and crosses- sectional study, 43 samples of deep wells were collected from 3 cities during2006-2010 . 15 parameters analyzed according to standard methods, comparing to the WHO standards. Results The results revealed the parameters of EC 625,992,650 &mu;mho/cm, TDS 273, 535,523 mg/l, Nitrate 9/7,10.9,9.9 mg/l, Sulfate 19, 25.6, 39.2 mg/l and Chloride 22, 182, 185 for Bandar Gaz, Bandar Torkaman and Kordkoy, respectively. Also, the average value of hardness in drinking water 185, 255 and 317 mg/l calcium carbonate for Bandar Gaz, Bandar Torkaman and Kordkoy, respectively. According to hardness of water quality Bandar Gaz and Bandar Torkaman, Kordkoy ranged between hard and very hard water group. Fluoride concentration ranged from 0.3 to 0.4 ppm, where 100% samples showed fluoride less than permissible limit. Conclusion According to results, the mean concentration of most physico -chemical parameters except fluoride concentration in Bandar Gaz, Bandar Torkaman and Kordkoy drinking water resources is within the Iran and WHO standard limitations. * Corresponding Author: Babol University of Medical Sciences, Department of Environmental Health Engineering. Email: [email protected]

Effect of modified lumbosacral orthoses on treatment of patients with spondylolysis

Introduction: In this study, the effect of modified lumbo sacral orthoses on lordosis andlumbosacral angle and reliving pain and functional disability was investigated.Materials and Methods: 30 patients (19 females, 11 males) with spondylolysis (aged between 22-57 years) were sampled in a simple randomized manner. They had a history of low back pain for 30.7(in average) months. Modified lumbo sacral orthoses was prescribed for 3 months (23 hours daily).The brace was unique, bridged between xyphoid process to pubic symphysis anteriorly and seventhlumbar vertebrae to gluteal prminency posteriorly.Results: Our results show that 3-months using the modified lumbo sacral orthoses resulted insignificant decrement in pain and improvement in functional ability of patients. Although lordosis andlumbosacral angles decreased to 2.21 and 0.92 degrees, respectively, but these changes were notsignificant. Finally, patients with the lower duration of low back pain showed better results.Conclusion: Our findings indicate that the modified lumbosacral orthoses, as a non-invasiveprocedure, can be used for conservative treatments in spondylolysis patients