Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf.

U radu je opisana izolacija pet sastojaka petroleterske i diklormetanske frakcije metanolnog ekstrakta kore biljke Delonix regia: lupeol (1), epilupeol (2), β-sitosterol (3), stigmasterol (4) i p-metoksibenzaldehid (5). Nadalje, testirano je antimikrobno djelovanje različitih ekstrakata difuzijskom metodom na disku (15 μg mm2). Zone inhibicije za sastojke topljive u petroleteru, tetraklormetanu i diklormetanu bile su 914 mm, 1113 mm, odnosno 920 mm, dok je zona inhibicije standarda kanamicina bila 2025 mm. U biološkom pokusu smrtnosti morskih kozica najveću toksičnost pokazali su spojevi topljivi u tetraklormetanu (LC50 = 0,83 μg mL1), dok je topljivost sastojaka topljivih u petroleteru i diklormetanu bila LC50 14,94, odnosno 3,29 μg mL1, a standarda vinkristin sulfata 0,812 μg mL1. Ovo je prvo izvješće o izolaciji sastojaka, antimikrobnom djelovanju i citotoksičnosti biljke D. regia.In this study five compounds, lupeol (1), epilupeol (2), β-sitosterol (3), stigmasterol (4) and p-methoxybenzaldehyde (5) were isolated from the petroleum ether and dichloromethane fractions of a methanolic extract of the stem bark of Delonix regia. Antimicrobial screening of the different extracts (15 μg mm2) was conducted by disc diffusion method. The zones of inhibition demonstrated by the petroleum ether, carbon tetrachloride and dichloromethane fractions ranged from 914 mm, 1113 mm and 920 mm, respectively, compared to kanamycin standard with the zone of inhibition of 2025 mm. In brine shrimp lethality bioassay, the carbon tetrachloride soluble materials demonstrated the highest toxicity with LC50 of 0.83 μg mL1, while petroleum ether and dichloromethane soluble partitionates of the methanolic extract revealed LC50 of 14.94 and 3.29 μg mL1, respectively, in comparison with standard vincristine sulphate with LC50 of 0.812 μg mL1. This is the first report on compounds separation from D. regia, their antimicrobial activity and cytotoxicity

Light propagation through closed-loop atomic media beyond the multiphoton resonance condition

The light propagation of a probe field pulse in a four-level double-lambda type system driven by laser fields that form a closed interaction loop is studied. Due to the finite frequency width of the probe pulse, a time-independent analysis relying on the multiphoton resonance assumption is insufficient. Thus we apply a Floquet decomposition of the equations of motion to solve the time-dependent problem beyond the multiphoton resonance condition. We find that the various Floquet components can be interpreted in terms of different scattering processes, and that the medium response oscillating in phase with the probe field in general is not phase-dependent. The phase dependence arises from a scattering of the coupling fields into the probe field mode at a frequency which in general differs from the probe field frequency. We thus conclude that in particular for short pulses with a large frequency width, inducing a closed loop interaction contour may not be advantageous, since otherwise the phase-dependent medium response may lead to a distortion of the pulse shape. Finally, using our time-dependent analysis, we demonstrate that both the closed-loop and the non-closed loop configuration allow for sub- and superluminal light propagation with small absorption or even gain. Further, we identify one of the coupling field Rabi frequencies as a control parameter that allows to conveniently switch between sub- and superluminal light propagation.Comment: 10 pages, 8 figure

Gambaran Kristal Hemoglobin pada Bercak Darah yang Terpapar pada Beberapa Zat Pembersih Lantai Domestik Non Karbol

Bloodstain is an evidence that often found in criminal case. Bloodstain which is found on a crime scene often already contaminated, there might be an effort to clean up the bloodstain on the floor by using floor cleaner agents. The exposure of cleaning agents potentially damaging membrane cell and denature protein inside the blood, so at the time when forensic examination of bloodstain has been done it is possible to generate different interpretations. This research is a descriptive research with experimental laboratory design to find out the description of haemoglobin crystal on bloodstain exposed by some non carbolic domestic floor cleaner agent using Teichmann test and Takayama test. This research shows that haemoglobin crystal can be found on eighty slide of bloodstain which has been flowed and swabbed by non carbolic domestic floor cleaner agents. The conclusion of this research is no effect of the exposure by non carbolic domestic floor cleaner agent against haemoglobin crystal description on the Teichmann and Takayama test

Spontaneous emission by rotating objects: A scattering approach

We study the quantum electrodynamics (QED) vacuum in the presence of a body rotating along its axis of symmetry and show that the object spontaneously emits energy if it is lossy. The radiated power is expressed as a general trace formula solely in terms of the scattering matrix, making an explicit connection to the conjecture of Zel'dovich [JETP Lett. 14, 180 (1971)] on rotating objects. We further show that a rotating body drags along nearby objects while making them spin parallel to its own rotation axis

Potentiometric Determination of Ketotifen Fumarate in Pharmaceutical Preparations and Urine Using Carbon Paste and PVC Membrane Selective Electrodes

This study compares between unmodified carbon paste (CPE; the paste has no ion pair) and polyvinyl chloride (PVC) membrane selective electrodes that were used in potentiometric determination of ketotifen fumarate (KTF), where sodium tetraphenylborate (NaTPB) was used as titrant. The performance characteristics of these sensors were evaluated according to IUPAC recommendations which reveal a fast, stable, and linear response for KTF over the concentration range of 10−7 to 10−2 mol L−1. The electrodes show Nernstian slope value of 52.51 ± 0.20 and 51.51 ± 0.25 mV decade−1 for CPE and PVC membrane electrodes at 30°C, respectively. The potential is nearly stable over the pH range 3.0–6.0 and 2.0–7.0 for CPE and PVC membrane electrodes, respectively. Selectivity coefficient values towards different inorganic cations, sugars, and amino acids reflect high selectivity of the prepared electrodes. The electrodes responses at different temperatures were also studied, and long operational lifetime of 12 and 5 weeks for CPE and PVC membrane electrodes, respectively, were found. These are used for determination of ketotifen fumarate using potentiometric titration, calibration, and standard addition methods in pure samples, its pharmaceutical preparations (Zaditen tablets), and biological fluid (urine). The direct potentiometric determination of KTF using the proposed sensors gave recoveries % of 98.97 ± 0.53 and 98.62 ± 0.74 with RSD 1.42 and 0.63% for CPE and PVC membrane selective electrodes, respectively. Validation of the method shows suitability of the proposed sensors for use in quality control assessment of KTF. The obtained results were in a good agreement with those obtained using the reported spectrophotometric method

A performance comparison of the contiguous allocation strategies in 3D mesh connected multicomputers

The performance of contiguous allocation strategies can be significantly affected by the distribution of job execution times. In this paper, the performance of the existing contiguous allocation strategies for 3D mesh multicomputers is re-visited in the context of heavy-tailed distributions (e.g., a Bounded Pareto distribution). The strategies are evaluated and compared using simulation experiments for both First-Come-First-Served (FCFS) and Shortest-Service-Demand (SSD) scheduling strategies under a variety of system loads and system sizes. The results show that the performance of the allocation strategies degrades considerably when job execution times follow a heavy-tailed distribution. Moreover, SSD copes much better than FCFS scheduling strategy in the presence of heavy-tailed job execution times. The results also show that the strategies that depend on a list of allocated sub-meshes for both allocation and deallocation have lower allocation overhead and deliver good system performance in terms of average turnaround time and mean system utilization

Group velocity control in the ultraviolet domain via interacting dark-state resonances

The propagation of a weak probe field in a laser-driven four-level atomic system is investigated. We choose mercury as our model system, where the probe transition is in the ultraviolet region. A high-resolution peak appears in the optical spectra due to the presence of interacting dark resonances. We show that this narrow peak leads to superluminal light propagation with strong absorption, and thus by itself is only of limited interest. But if in addition a weak incoherent pump field is applied to the probe transition, then the peak structure can be changed such that both sub- and superluminal light propagation or a negative group velocity can be achieved without absorption, controlled by the incoherent pumping strength

Relativistic and Binding Energy Corrections to Direct Photon Production In Upsilon Decay

A systematic gauge-invariant method is used to calculate the rate for an upsilon meson to decay inclusively into a prompt photon. An expansion is made in the quark relative velocity v, which is a small natural parameter for heavy quark systems. Inclusion of these O(v^2) corrections tends to increase the photon rate in the middle z range and to lower it for larger z, a feature supported by the data.Comment: 13 pages, LateX, One figure (to be published in Phys. Rev. D, Sept. 1, 1996

Inclusive dileptonic rare B decays with an extra generation of vector-like quarks

We investigate the leading effects of extending the Standard Model of electroweak interactions by an extra iso-singlet up- and down- type quark pair on various distributions and total branching ratio of the inclusive B-> X_s l^+ l^- (l =e,\mu) rare B decays. The presence of the extra vector-like down quark $D$ results in the non-unitarity of the extended quark mixing matrix V, which in turn leads to b-> s FCNC at the tree level proportional to (V^\dagger V)_{sb}. On the other hand, the effective penguin and box vertex functions are sensitive to the mass of the extra iso-singlet up quark m_U. The experimental upper bound on BR(B-> X_s \mu^+ \mu^-) is used to constrain the parameters of the model. It is shown that the shapes of the differential branching ratio and forward-backward asymmetry distribution are very sensitive to the value of the model parameters. We also calculate the CP aymmetry distribution of the dileptonic decay in the vector-like quark model. It is shown that, for a typical choice of the model parameters, asymmetries up to around 10% can be achieved for certain values of the dilepton invariant mass.Comment: 15 pages, 2 figure

Instability and Fluctuations of Flux Lines with Point Impurities in a Parallel Current

A parallel current can destabilize a single flux line (FL), or an array of FLs. We consider the effects of pinning by point impurities on this instability. The presence of impurities destroys the long-range order of a flux lattice, leading to the so called Bragg glass (BrG) phase. We first show that the long-range topological order of the BrG is also destroyed by a parallel current. Nonetheless, some degree of short-range order should remain, whose destruction by thermal and impurity fluctuations, as well as the current, is studied here. To this end, we employ a cage model for a single FL in the presence of impurities and current, and study it analytically (by replica variational methods), and numerically (using a transfer matrix technique). The results are in good agreement, and in conjunction with a Lindemann criterion, provide the boundary in the magnetic field--temperature plane for destruction of short-range order. In all cases, we find that the addition of impurities or current (singly or in combination) leads to further increase in equilibrium FL fluctuations. Thus pinning to point impurities does not stabilize FLs in a parallel current $j_z$, although the onset of this instability is much delayed due to large potential barriers that diverge as $j_z^{-\mu}$.Comment: 10 pages, 6 figure