Which therapies will provide the best results in IBS

Irritable Bowel Syndrome (IBS) is a chronic abdominal pain with the change of defecation. The present study aimed to compare the effects of standard medical treatment plus stress management treatment and standard medical treatment alone in IBS symptoms and quality of life. An experimental study has been carried out among participants with Rome-III diagnostic criteria. Participants randomly assigned into two groups. The case group received the standard medical treatment plus stress management treatment, n= 15, while, the control group received the standard medical treatment alone, n= 15. The training programs were contain 8 domains of relaxation, cognation reproduce, contrast skills training, express trains and problem solving, anger management training and social supports. Data were collected using demographic, ROME III, Bowel Syndrome Symptom Severity Score and Quality of Life- IBS. Overall, 30 male participants were evaluated. The age range of participants was 25-55 years. The stress management training could decrease the ROME-II scores. Also the stress management training has a significant effect on quality of life and the HSE. Therefore, it is necessary that IBS suffering referred to psychologists for psychotherapy while they are under medical treatment

Epidemiological aspects of suicide lead to death in Iranian population during 2004-2008; A retrospective study

Suicide is raised in many countries around the world as one of the major problems in medical and social advocacy. The increasing incidence of suicide in the community is sensible and irreparable damage to the body of a society's human resources. Therefore the present study aimed to explore the epidemiological aspects of suicide leads to death in Iranian population during 2004-2008. In a retrospective study a census sampling method was used. All records formed of suicide death in Ilam province during 2004 to 2008 in the Office of the State Coroner were evaluated. Data was collected by a checklist including age, gender, marital status, educational level, occupation, number of families, suicide instrument location of attempted to suicide, place of death and season. SPSS software Package 14 was used to analyze the data of this project. Mean± SD, median and percentages were used to describe the data. The average percentage of suicide lead to death in Ilam province was 18.7 per 100.000 person's .Women and men have a suicide rate roughly equal (50.8 and 49.2). There was a significant relationship between month (P= 0.02), season (P= 0.03), the number of families (P= 0.001) and percentage of suicide lead to death. Self-burning was the most common method used by suicide lead to death. This study showed that suicide remains a serious problem and an increase occurred in suicide in Ilam province in comparison with previous years

Effects of single and combined supplementation of Lactobacillus plantarum with dietary xylooligosaccharide on growth performance, body composition and physiological responses of sobaity (Sparidentex hasta) fingerling

The aim of this study was to evaluate the single and combined effects of dietary probiotic with prebiotic on growth performance, non-specific immune response, body composition, digestive enzymes activity and intestine bacterial flora of sobaity fingerling (Sparidentex hasta). For this purpose, 425 individuals of sobaity fingerlings were prepared with an average weight of 7.64 ± 0.3 g from the Mariculture Research Station of South Iranian Aquaculture Research Center. This study was carried out in a completely randomized design with four treatments and three replications (45 fish per each replication) in fiberglass tanks with 300 liters volume. Fish were fed with feed containing 0 (control group), 10^6 CFU probiotic per gram feed (treatment 1), 0.5 and 1 percent prebiotic plus10^6 CFU probiotic per gram feed (treatment 2 and 3) at 4.5 percent of body weight for a period of 42 days. At the end of the experiment, body composition, intestine, blood, plasma and mucus samples were collected. The obtained results indicated that dietary prebiotic and probiotic did not change growth performance, intestine bacterial flora and non-specific immune response of sobaity (P > 0.05). Nonetheless, plasma bactericidal activity of control group was significantly higher that treatment 3 (P < 0.05). Moisture and protein content of treatment 2 showed significant different compared to the control group (P < 0.05). The results of this study showed that digestive enzymes activity including alkaline protease, amylse and lipase affected by administration of dietary prebiotic and probiotic (P < 0.05). Overall, this study showed that single supplementation of probiotic and combination with prebiotic at the used amounts had no positive effects on growth performance and intestine bacterial flora and immune response (except plasma bactericidal activity) of sobaity but improve digestive enzymes activity

Dietary intake and lifestyle behavior in different phenotypes of polycystic ovarian syndrome: a case-control study

Objective: To compare dietary intake and lifestyle behaviour in women with polycystic ovarian syndrome (PCOS) and healthy women. Methods: 160 healthy women (partner with male infertility) were recruited to a control group; 168 women with PCOS (diagnosed on ultrasound) were recruited to a case study group for this cross-sectional comparative study. The case group was classified into three phenotypes based on presence or absence of menstrual disorder (M), hyperandrogenism (HA), and polycystic ovary according to sonography (PCO): HA+PCO (n=53), PCO+M (n=57) and M+HA+PCO (n=66). Dietary intake and lifestyle behaviour were measured using a food frequency questionnaire (FFQ) and a lifestyle questionnaire (LQ). Results: The mean energy (P<0.001) and fat intake (P<0.001) were greater in PCOS groups compared with the control group. The average energy and fat intake were greater in HA+M+PCO group after age and BMI adjustment compared with other phenotypes (P<0.001). In comparison with the control group, lifestyle scores were lower in the PCOS group in the fields of physical activity, weight and nutrition control after age and BMI adjustment (P<0.001). The average score of lifestyle in the fields of physical activity, weight and nutrition control, and psychological health was lower in the phenotype HA+M+PCO compared with other phenotypes (P<0.001). Conclusions: Limited energy and fat intake is strongly recommended in Iranian women with PCOS especially in phenotype HA+M+PCO. Consultation on improvement of psychological health and the importance of weight and nutrition control, and appropriate physical activity in patients especially in HA+M+PCO is advocated. Keywords: Lifestyle, polycystic ovarian syndrome, die

Genetic characterization of Vimba vimba persa in southern part of the Caspian Sea using microsatellite marker

Population genetic structure of Vimba vimba persa was investigated using microsatellite markers from 4 regions along the Iranian coastline of Southern the Caspian Sea (Anzali lagoon & havigh River in Gilan province, BabolRoud River in Maz&eran province & GorganRoud River in Golestan province). Genomic DNA from 121 specimens was extracted from fin tissue by phenol-Chlorophorm method & PCR reaction was accomplished with 17 microsatellite primers, out of 17 microsatellite primers 14 loci were amplified, in which 10 of them were amplified with reasonable polymorphism & 4 were monomorphism. Totally 302 alleles were identified on average 7.5 Observed & expected heterozygosity averages were 0.80 & 0.77 respectively. Most cases significantly deviated from Hardy-Weinberg equilibrium (p 0.01). The estimation of Fst (p 0.01) revealed significant population structuring & estimate four population of Vimba vimba persa is identified in the Caspian Sea. These studies were to apply & develop population genetic approaches to assist conservation, sustainable harvest & restocking of these populations

Inheritance of microsatellite markers in the hybrid of female Chalcalburnus chalcoides and male Vimba vimba persa Chalcalburnus chalcoides (Gueldenstaedt, 1772) ×Vimba vimba persa (Pallas, 1814)

The Mendelian Inheritance of produced hybrids from Chalcalburnus chalcoides and Vimba vimba persa was investigated using Microsatellite Markers. Genomic DNA from the produced larva and also small piece of dorsal and pectoral fin of their parents were extracted by Phenol-Chlorophorm method and PCR reaction was accomplished. 10 loci were amplified, in which 7 of them were amplified with reasonable polymorphism and 3 were monomorphism. In order to study the segregation of the produced F1 hybrids from female Chalcalburnus chalcoides and male Vimba vimba persa, seven loci (LCO3, LCO1, Lid11, Rru2, Z1-2, Z7-8, and Z9-10) were used. According to the results it showed that parents and F1 larva‘s allelic distribution were almost segregated based on Mendelian inheritance in 7 loci. The present study showed that Microsatellite markers are useful marker in study of inheritance

Prevalence and gender differences in psychiatric disorders and DSM-IV mental disorders: a population-based study

Background: The early diagnosis of psychiatric disorders is critical as it improves the chance of recovery for patients. The aim of this study was to determine gender disparities in psychiatric and mental disorders in adult persons and to examine the validity of the 28-item General Health Questionnaire (GHQ-28; Persian version) in the diagnosis of patients with suspected psychiatric disorders, along with receiver operating characteristic (ROC) analysis. Materials and Methods: The cross-sectional study was conducted using cluster random sampling method in three steps. Subjects were screened by GHQ-28 and then evaluated by Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR) for diagnosis/classification of mental disorders. Chisquare test and independent t-test were used for statistical analysis. The ROC curve was used to assess cut-off points. Results: Of the 763 participants (aged 15 and above), 25.8 of responders demonstrated characteristics of psychological distress; the prevalence in males and females were 20.9 and 29.8, respectively. The common mental disorders in males were anxiety disorder (18.2), followed by any major depressive disorder (MDD) (17.4. ), and compulsive disorder (10.0). In females, the common mental disorders were anxiety disorder (23.6), followed by any MDD (22.7), compulsive disorder (13.9), phobia disorder (10.4) and psychotic disorder (6.1). ROC analysis showed that 91.7 of suspected persons had a mental disorder as assessed by DSM-IV-TR. Conclusion: The present study verifies the validity of the Persian version of the GHQ-28 as a screening tool to determine psychiatric disorders in persons of age 15 and above. The rate of psychiatric disorders in this study is higher than the mean national rate

Relationship between internet addiction and mental health in adolescents

BACKGROUND: Internet addiction (IA) currently is the major public health concern, especially in adolescents, although the results of previous reports are not generally uniform. This study was conducted to determine IA in adolescents and to examine the correlation of IA with mental health in adolescents. METHODS: This cross-sectional study was conducted in 2019 in Ilam city. In this study, 362 persons were included using stratified cluster sampling; clusters were geographical area and schools. The valid questionnaires including Internet Addiction Test and 28-item General Health Questionnaire (GHQ-28) were used to interview. The correlation statistical technique was used to determine the association between the two variables. The significance level was considered <0.05. RESULTS: The mean +/- standard deviation age of the responders was 16.40 +/- 2.47 years; the total score of IA and mental health was 43.02 +/- 16.50 and 19.27 +/- 9.72, respectively. We found that 5.5 of the adolescents had a severe level of IA. The lack of control with anxiety, neglect work and social dysfunction, and neglect social life and severe depression in internet users were found to be statistically significant: r (365) = 0.151, P < 0.033; r (365) = 0.126, P < 0.021; and r (365) = 0.125, P < 0.033, two-tailed, respectively. CONCLUSION: According to the results, the excessive use of internet, lack of control, and neglect social life are significantly correlated with mental health in adolescents; these results could be contribute to improve the theoretical models for IA in adolescents