Biophysics of Lower Back Pain

Lower back pain is one of the most predominant problems in the general public. It has been traditionally regarded as a mechanical problem by both orthodox and complementary practitioners. This study was conducted to evaluate the lumbosacral angle which is an inherent cause of lower back pain and also investigate the shearing and compressing forces on the lumbar spine. The study was carried out at in a Hospital within the …. Metropolis. A total of 210 patients’ data consisting of 72 males and 138 females was considered. The lumbosacral angle was measured using Ferguson’s method with the MicroDicom software. Patients were grouped into ages; 0 – 20, 21 – 30, 31 – 40, 41 – 50, 51 – 60, 61 – 70, 71 – 80 and 81 – 100. The number of patients in each age group was; 7, 12, 26, 28, 56, 27, 11 and 7 respectively. The average lumbosacral angle evaluated, according to age group was; 36.3º, 39º, 35.81º, 36.23º, 36.55º, 37.5º, 35.89 º and 34.92º. The overall lumbosacral mean was determined to be 36.50º. The lumbosacral angle evaluated was used to determine the corresponding compressive and shear forces at the lumbar region which are the principal predictors of the lower back pain

Blount disease and familial inheritance in Ghana, area cross-sectional study

Objective The objective of this study is to study familial inheritance for Blount disease to create better understanding of the aetiology of Blount disease.Methods After reviewing patient files and conventional roentgenologic imaging, 139 patients with Blount disease were included in this cross-sectional study, of which 102 patients were interviewed. During the interviews, patient characteristics and family history were collected. Blood samples were taken from five patients and three families and a whole exome sequencing was performed.Results Although patients came from all over the country, 90% of the patients belonged to the Akan tribe. A positive family history was found in 63 families (62%), of which, almost two-third had a positive family history in a first-degree family member. In most of the cases (64%), the varus legs resolved over time. In 9%, severe bowing remained ‘just like the patient’. The results of the whole exome sequencing did not show a genetic predisposition.Conclusion This study describes a large group of Blount patients. Because of the high numbers of positive family history and the centralisation of patients in the Akan region, a familial predisposition is suggested. Further genetic research is essential for better understanding of the possible multifactorial aetiology in Blount disease