7 research outputs found

    Enhancing response farming for strategic and tactical management of risks of seasonal rainfall variability

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    African Crop Science Journal 2014, Vol. 22, Issue Supplement s4: pp. 941 - 950Seasonal rainfall variability, particularly the uncertainty with respect to the direction and extent that variability will assume in a given season, forms the greatest source of risk to crop production in semi-arid areas of Ethiopia. Equipping vulnerable communities, in advance, with the expected date of onset of a cropping season, is crucial for smallholder farmers to better prepare to respond and manage the uncertainties. Therefore, rainfall prediction, particularly development of models that can foretell the date of onset of next cropping season is crucial in facilitating strategic agronomic planning and tactical management of in-season risks. A twenty-four-year climatic data study was conducted for Melkassa Agricultural Research Centre (MARC) in semi arid Ethiopia, to develop onset date prediction models that can improve strategic and tactical response farming (RF). A sequential simulation model for a build up of 15 to 25 mm soil water by April 1st, was conducted. Simulation results revealed a build up of soil water up to 25 mm, to be the most risk-wise acceptable time of season onset for planting of a 150-day maize crop. In the context of response farming, this was desirable as it offers the opportunity for farmers to consider flexible combination production of maize (Zea mays L.) varieties of 120 and 90 days in the event of failure of earliest sown 150-day maize crop. Thus, to allow for flexible combination production of the three maize varieties, predictive capacity was found crucial for April onset of the next crop season. Accordingly, based on the consideration of pre-onset rainfall parameters, the first effective rainfall date varied considerably with the date of onset of rainfall. Regression analyses revealed the first effective rainfall date to be the best predictor of the date of onset (R2 = 62.5%), and a good indicator of the duration of next season (R2 = 42.4%). The identified strategic predictor, the first effective rainfall date, enabled prediction of time of season onset and season length by a lead time of two to three months. This markedly improved Stewart’s RF. The date of onset of the next crop season was also found to be a useful predictor of season duration (R2 = 87.3%). Strategic agronomic planning should be adjusted according to the first effective rain date, and tactically according to what date of rainfall onset informs us about expectations in the duration and total season water supply

    Children’s Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial

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    Background: To prevent poor long-term outcomes (deaths and readmissions) the integrated global action plan for pneumonia and diarrhoea recommends under the ‘Treat’ element of Protect, Prevent and Treat interventions the importance of continued feeding but gives no specific recommendations for nutritional support. Early nutritional support has been practiced in a wide variety of critically ill patients to provide vital cell substrates, antioxidants, vitamins, and minerals essential for normal cell function and decreasing hypermetabolism. We hypothesise that the excess post-discharge mortality associated with pneumonia may relate to the catabolic response and muscle wasting induced by severe infection and inadequacy of the diet to aid recovery. We suggest that providing additional energy-rich, protein, fat and micronutrient ready-to-use therapeutic feeds (RUTF) to help meet additional nutritional requirements may improve outcome. Methods: COAST-Nutrition is an open, multicentre, Phase II randomised controlled trial in children aged 6 months to 12 years hospitalised with suspected severe pneumonia (and hypoxaemia, SpO2 <92%) to establish whether supplementary feeds with RUTF given in addition to usual diet for 56-days (experimental) improves outcomes at 90-days compared to usual diet alone (control). Primary endpoint is change in mid-upper arm circumference (MUAC) at 90 days and/or as a composite with 90-day mortality. Secondary outcomes include anthropometric status, mortality, readmission at days 28 and 180. The trial will be conducted in four sites in two countries (Uganda and Kenya) enrolling 840 children followed up to 180 days. Ancillary studies include cost-economic analysis, molecular characterisation of bacterial and viral pathogens, evaluation of putative biomarkers of pneumonia, assessment of muscle and fat mass and host genetic studies. Discussion: This study is the first step in providing an option for nutritional support following severe pneumonia and will help in the design of a large Phase III trial. Registration: ISRCTN10829073 (6th June 2018) PACTR202106635355751 (2nd June 2021

    Children’s Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial

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    Background: To prevent poor long-term outcomes (deaths and readmissions) the integrated global action plan for pneumonia and diarrhoea recommends under the ‘Treat’ element of Protect, Prevent and Treat interventions the importance of continued feeding but gives no specific recommendations for nutritional support. Early nutritional support has been practiced in a wide variety of critically ill patients to provide vital cell substrates, antioxidants, vitamins, and minerals essential for normal cell function and decreasing hypermetabolism. We hypothesise that the excess post-discharge mortality associated with pneumonia may relate to the catabolic response and muscle wasting induced by severe infection and inadequacy of the diet to aid recovery. We suggest that providing additional energy-rich, protein, fat and micronutrient ready-to-use therapeutic feeds (RUTF) to help meet additional nutritional requirements may improve outcome. Methods: COAST-Nutrition is an open, multicentre, Phase II randomised controlled trial in children aged 6 months to 12 years hospitalised with suspected severe pneumonia (and hypoxaemia, SpO2 <92%) to establish whether supplementary feeds with RUTF given in addition to usual diet for 56-days (experimental) improves outcomes at 90-days compared to usual diet alone (control). Primary endpoint is change in mid-upper arm circumference (MUAC) at 90 days and/or as a composite with 90-day mortality. Secondary outcomes include anthropometric status, mortality, readmission at days 28 and 180. The trial will be conducted in four sites in two countries (Uganda and Kenya) enrolling 840 children followed up to 180 days. Ancillary studies include cost-economic analysis, molecular characterisation of bacterial and viral pathogens, evaluation of putative biomarkers of pneumonia, assessment of muscle and fat mass and host genetic studies. Discussion: This study is the first step in providing an option for nutritional support following severe pneumonia and will help in the design of a large Phase III trial. Registration: ISRCTN10829073 (6th June 2018) PACTR202106635355751 (2nd June 2021
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