8 research outputs found
Impact of the Spruce Budworm (Lepidoptera: Tortricidae) on the Ottawa and Hiawatha National Forests, 1978-1980
The Michigan Impact Plot System was established during 1978 and 1979 to obtain a data base for quantifying the impact of the spruce budworm in the Ottawa and Hiawatha National Forests. The formulae used to estimate the mean, total, and associated standard errors of the various parameters at the national forest and forest district levels are presented. We present the 1978, 1979, and 1980 impact data for the following parameters; percent mortality, total dead volume. dead volume per ha, live volume per ha, defoliation ranking, frequency and extent of top-kill, and incidence of spruce budworm feeding on saplings and regenera- tion. Statistics from an annual inventory of 108 composite ground sampling units (CGSU) in 1978, and 136 CGSU\u27s in 1979 and 1980 provide a more precise estimate ofthe impact of the spruce budworm in Michigan\u27s Upper Peninsula than ha~ been available to date
Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination.
Abstract
OBJECTIVE:
We characterised the clinical course, treatment and outcomes in 59 patients with relapsing myelin oligodendrocyte glycoprotein (MOG) antibody-associated demyelination.
METHODS:
We evaluated clinical phenotypes, annualised relapse rates (ARR) prior and on immunotherapy and Expanded Disability Status Scale (EDSS), in 218 demyelinating episodes from 33 paediatric and 26 adult patients.
RESULTS:
The most common initial presentation in the cohort was optic neuritis (ON) in 54% (bilateral (BON) 32%, unilateral (UON) 22%), followed by acute disseminated encephalomyelitis (ADEM) (20%), which occurred exclusively in children. ON was the dominant phenotype (UON 35%, BON 19%) of all clinical episodes. 109/226 (48%) MRIs had no brain lesions. Patients were steroid responsive, but 70% of episodes treated with oral prednisone relapsed, particularly at doses <10\u2009mg daily or within 2 months of cessation. Immunotherapy, including maintenance prednisone (P=0.0004), intravenous immunoglobulin, rituximab and mycophenolate, all reduced median ARRs on-treatment. Treatment failure rates were lower in patients on maintenance steroids (5%) compared with non-steroidal maintenance immunotherapy (38%) (P=0.016). 58% of patients experienced residual disability (average follow-up 61 months, visual loss in 24%). Patients with ON were less likely to have sustained disability defined by a final EDSS of 652 (OR 0.15, P=0.032), while those who had any myelitis were more likely to have sustained residual deficits (OR 3.56, P=0.077).
CONCLUSION:
Relapsing MOG antibody-associated demyelination is strongly associated with ON across all age groups and ADEM in children. Patients are highly responsive to steroids, but vulnerable to relapse on steroid reduction and cessation
New Era of Air Quality Monitoring from Space: Geostationary Environment Monitoring Spectrometer (GEMS)
GEMS will monitor air quality over Asia at unprecedented spatial and temporal resolution from GEO for the first time, providing column measurements of aerosol, ozone and their precursors (nitrogen dioxide, sulfur dioxide and formaldehyde).
Geostationary Environment Monitoring Spectrometer (GEMS) is scheduled for launch in late 2019 - early 2020 to monitor Air Quality (AQ) at an unprecedented spatial and temporal resolution from a Geostationary Earth Orbit (GEO) for the first time. With the development of UV-visible spectrometers at sub-nm spectral resolution and sophisticated retrieval algorithms, estimates of the column amounts of atmospheric pollutants (O3, NO2, SO2, HCHO, CHOCHO and aerosols) can be obtained. To date, all the UV-visible satellite missions monitoring air quality have been in Low Earth orbit (LEO), allowing one to two observations per day. With UV-visible instruments on GEO platforms, the diurnal variations of these pollutants can now be determined. Details of the GEMS mission are presented, including instrumentation, scientific algorithms, predicted performance, and applications for air quality forecasts through data assimilation. GEMS will be onboard the GEO-KOMPSAT-2 satellite series, which also hosts the Advanced Meteorological Imager (AMI) and Geostationary Ocean Color Imager (GOCI)-2. These three instruments will provide synergistic science products to better understand air quality, meteorology, the long-range transport of air pollutants, emission source distributions, and chemical processes. Faster sampling rates at higher spatial resolution will increase the probability of finding cloud-free pixels, leading to more observations of aerosols and trace gases than is possible from LEO. GEMS will be joined by NASA's TEMPO and ESA's Sentinel-4 to form a GEO AQ satellite constellation in early 2020s, coordinated by the Committee on Earth Observation Satellites (CEOS)
Timely Colonoscopy After Positive Fecal Immunochemical Tests in the Veterans Health Administration: A Qualitative Assessment of Current Practice and Perceived Barriers.
IntroductionThe Veterans Health Administration introduced a clinical reminder system in 2018 to help address process gaps in colorectal cancer screening, including the diagnostic evaluation of positive fecal immunochemical test (FIT) results. We conducted a qualitative study to explore the differences between facilities who performed in the top vs bottom decile for follow-up colonoscopy.MethodsSeventeen semistructured interviews with gastroenterology (GI) providers and staff were conducted at 9 high-performing and 8 low-performing sites.ResultsWe identified 2 domains, current practices and perceived barriers, and most findings were described by both high- and low-performing sites. Findings exclusive to 1 group mainly pertained to current practices, especially arranging colonoscopy for FIT-positive patients. We observed only 1 difference in the perceived barriers domain, which pertained to primary care providers.DiscussionThese results suggest that what primarily distinguishes high- and low-performing sites is not a difference in barriers but rather in the GI clinical care process. Developing and disseminating patient education materials about the importance of diagnostic colonoscopy, eliminating in-person precolonoscopy visits when clinically appropriate, and involving GI in missed colonoscopy appointments and outside referrals should all be considered to increase follow-up colonoscopy rates. Our study illustrates the challenges of performing a timely colonoscopy after a positive FIT result and provides insights on improving the clinical care process for patients who are at substantially increased risk for colorectal cancer
A discourse-analytical perspective on sustainability assessment: interpreting sustainable development in practice
Sustainable development is a ubiquitously used concept in public decision-making: it refers to an ideal vision of global society where human development and environmental quality go hand in hand. Logically, any decision-supporting process aiming at facilitating and steering society toward a sustainable future then seems desirable. Assessing the sustainability of policy decisions is, however, influenced by what sustainable development is believed to entail, as different discourses coexist under the umbrella of the sustainable development meta-discourse. This paper proposes a typology of sustainable development discourses, and, subsequently, applies a discourse-analytical lens on two practical cases of sustainability assessment in different institutional and geographical contexts (in Belgium and in Benin). The results indicate that sustainability assessments tend to be influenced mainly by the consensual 'sustainable development as integration' discourse, while also providing a forum for dialogue between different discourses. The results shed light on context-specific discursive and institutional dynamics for the development and application of sustainability assessment. Acknowledging these dynamics as well as sustainable development's inherent interpretational limits can lead to an improved use of sustainable development as a decision-guiding strategy. © 2012 Springer.(IF52011 = 1.598; IF2011 = 0.886; CHL = 3.7).SCOPUS: ar.jinfo:eu-repo/semantics/publishe