413 research outputs found

    Seismogeological Features of the Crust in Romania

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    The Romanian area consists of old consolidated units of pre-Alpine age (the Moesian, Moldavian and Scythian platforms) and Alpine orogenic units (the Carpathian arc and North-Dobrudjan orogen). General seismogeological peculiarities of the pre-Alpine tectonic units are presented, as well as some structural characteristics of the Transylvanian Basin and the Pannonian Depression. Both shallow and deep seismic reflection/refraction data as well as log information and some potential field data were used for the investigation of the crustal structure. The varibility in the seismogeological pattern and crustal thickness shown by the different tectonic units is due to the differences in structure and lithology as well as to differences in crustal age. Some general characteristics are presented as an overall seismogeological image

    Особенности клинических форм и возможности диагностики болезни Вильсона в Республике Молдова

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    Centrul Naţional de Sănătate a Reproducerii şi Genetică Medicală, ChişinăuWilson’s disease (WD) is an autosomal recessive disorder of copper transport caused by a defect in the ATP7B gene. The disorder manifests as chronic liver disease and/or neurological impairment due to accumulation of copper in several tissues, principally in the liver and brain. The aim of the study was to evaluate the clinical forms and diagnostic methods of WD. We analyzed 35 Moldavan patients with WD. The diagnosis was established in any patients with unexplained liver disease along with neurological or neuropsychiatric disorder, presenting of Kayser-Fleischer rings, low serum ceruloplasmin level, the amount of copper excreted in the urine in a 24-hour period. Functional hepatic tests and others date of laboratory was obtained with standard methods. Initial clinical manifestation were hepatic in 10 (28.6%) patients, 19 (54.3%) were with neurological disorder, 6 (17.1%) patients presented mix hepatic and neuropsychiatric disturbance. Only in 2 (5.7%) patients the initial clinical manifestation was with psychiatric disturbance. Of the patients with neurological and mix disorder, 10 (40%) were with moderate liver disorder and only 5 (20%) with chronic liver disease. The neurological function was categoriezed as severe in 11 (44%) cases and moderate in 13 (52%) patients. Of the Moldovan patients, 71% have mix hepatic and neuropsychiatric forms with predomination of neurological disturbance average of 20 years. The difficulty in family screening could be solved with access to molecular diagnosis. Болезнь Вильсона (БВ) представляет собой аутосомно-рецессивное заболевание, связанное с нарушением транспорта меди, вызванное повреждением гена АТР7В. Клинические проявления заболевания являются результатом аккумуляции меди в различных органах и тканях, в основном в печени, головном мозге, роговице глаза и почках. Этим определяется многообразие клинических проявлений, а следовательно, и трудности ее диагностики. Мы обследовали 35 пациентов. Диагноз был поставлен всем пациентам с необъяснимыми печеночными нарушениями в комбинации с неврологическими и/или психическими изменениями, наличием кольца Кайзера-Флейшера, низким уровнем церулоплазмина в сыворотке крови, повышенной экскрецией меди в моче в течение 24 часов. Был проведен анализ клинических форм наиболее часто встречающихся на территории Молдовы и методов диагностики, позволяющих наиболее точно и вовремя установить диагноз. Установлено, что у 71% пациентов с БВ преобладают неврологические изменения в возрасте около 20 лет, что связано с поздней диагностикой. Трудности семейного скрининга могут быть разрешены с помощью молекулярной диагностики

    IDENTIFICATION OF LAND DEGRADATION AREAS BY QUERYING THE GEOREFERENCED NATIONAL DATABASES IN ORDER TO DELINEATE THE POTENTIAL LAND RECLAMATION PERIMETERS AT LOCAL LEVEL

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    The aim of this paper is to identify land degradation areas at administrative local level using GIS-based methods and geo-referenced databases including soil, geology, terrain, land use, and land cover data. The Local Administrative Unit of Scorțoasa, Buzău County, was selected as study case, covering an area of about 9595 ha of hill landscape. With data which included soil maps, land use maps and geology maps at medium scales (1:200 000) land degradation map was obtained for cropland and grazing land based on some attributes such as: water erosion, wind erosion, landslides,  salinization, water logging. The combined land degradation map, joining the different data, presents a medium resolution, given the different initial scales of the used maps. The approach adopted in this paper consisting in combining different data sets, requires field validation, but can provide primary reliable information for delineation of potential land reclamation areas

    Meat Product Reformulation: Nutritional Benefits and Effects on Human Health

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    This chapter aims to present the current state of the art in the field of meat product reformulation with respect to issues concerning the nutritional improvement and overall health benefits of such products. Our research team has recently finalised a national research project concerning this topic, and we feel that other food scientists could benefit from the theoretical and practical knowledge gathered during this time. The chapter will be divided into four subchapters. The first subsection will present the main targets of meat reformulation, such as lipid or protein profile modification, the use of bioactive compounds as additives, etc. The second subsection will discuss the bioavailability and bioaccessibility of carotenoids, phenolic compounds and other bioactive compounds, presenting these parameters from a nutraceutical perspective. The last subsections will include reported consumer attitudes. In this work, we will present data that could aid scientists in the field of food science to better grasp notions concerning consumer benefit, such as bioavailability, not only of a specific bioactive compound but also as part of a complex food matrix
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