A novel method to determine dynamic temperature trends applied to in-shoe temperature data during walking

Body temperature is one of the fundamental measures considered in the assessment of health and wellbeing, with various medical conditions known to give rise to abnormal changes in temperature. In particular, abnormal variations in dynamic temperature patterns during walking or exercise may be linked to a range of foot problems, which are of particular concern in diabetic patients. A number of studies have investigated normative temperature patterns of a population by considering data from multiple participants and averaging results after an acclimatisation interval. In this work we demonstrate that the temperature patterns obtained using such an approach may not be truly representative of temperature changes in a population, and the averaging process adopted may yield skewed results. In this work we propose an alternative approach to determine generic reference temperature patterns based on a minimization of root mean square differences between time-shifted versions of temperature data collected from multiple participants. The results obtained indicate that this approach can yield a general trend that is more representative of actual temperature changes across a population than conventional averaging methods. The method we propose is also shown to better capture and link the effects of underlying factors that influence dynamic temperature trends, which could in turn lead to a better understanding of underlying physiological phenomena

A Comparison between Rotating Squares and Anti-Tetrachiral Systems: Influence of Ligaments on the Multi-Axial Mechanical Response

Rotating unit systems are one of the most important and well-known classes of auxetic mechanical metamaterials. As their name implies, when loaded, these systems deform primarily via rotation of blocks of material, which may be connected together either directly through joints (or ‘joint-like’ connections made by overlapping vertices of the rotating units) as in the case of rotating rigid polygonal-unit systems or by ligaments/ribs as in the case of chiral honeycombs. In this work, we used Finite Element Analysis to investigate the effect which the presence/absence of ligaments has on the on-axis and off-axis mechanical properties of these systems by analysing two of the most well-known structures which characterise these two cases: the rotating square system and the anti-tetrachiral honeycomb. It was found that while the presence of ligaments has a negligible effect on the on-axis Poisson’s ratio of these systems, it has a profound influence on nearly all other mechanical properties as well as on the off-axis loading behaviour. Systems with ligaments were found to exhibit a high level of anisotropy and also a severely reduced level of stiffness in comparison to their non-ligamented counterparts. On the other hand, the rotating square system suffers from high localized stress-intensities and has a very low strain-tolerance threshold. In addition, an optimized ‘hybrid’ geometry which is specifically designed to capture the best features of both the anti-tetrachiral and rotating square system, was also analysed. This work shows the main differences between ligament-based and non-ligament-based auxetic structures and also highlights the importance of considering the off-axis mechanical response in addition to the on-axis properties when investigating such systems

Development and prototyping of SMA-metamaterial biaxial composite actuators

Shape memory alloys (SMA) are excellent candidates for implementation in actuator systems due to their ability to recover their original shape after high-strain loading through a thermally-induced phase transition. In this work, we propose and develop a novel SMA-metamaterial actuator which is capable of exhibiting a reversible, global elongation in multiple directions induced by the unidirectional contraction upon heating of a single SMA component. This actuator consists of (a) an SMA component, (b) a bias component and (c) the metamaterial geometry, with each component having a distinct function: (a) actuation activation, (b) reversibility of actuation upon deactivation and (c) amplifying and re-directing the uni-directional SMA actuation globally throughout the actuator, respectively. A prototype actuator was designed and tested in various configurations over multiple activation/deactivation cycles in order to demonstrate the functionality and reusability of this system. Furthermore, a theoretical model which predicts the actuation stroke of the system on the basis of the material properties of the SMA and bias components as well as the geometry of the metamaterial system was developed and validated. The findings of this work demonstrate the considerable potential of SMA-metamaterial actuators for implementation in systems requiring a multi-axial actuation output

Assimilating compact phase space retrievals (CPSRs): comparison with independent observations (MOZAIC in situ and IASI retrievals) and extension to assimilation of truncated retrieval profiles

Assimilation of atmospheric composition retrievals presents computational challenges due to their high data volume and often sparse information density. Assimilation of compact phase space retrievals (CPSRs) meets those challenges and offers a promising alternative to assimilation of raw retrievals at reduced computational cost (Mizzi et al., 2016). This paper compares analysis and forecast results from assimilation of Terra/Measurement of Pollution in the Troposphere (MOPITT) carbon monoxide (CO) CPSRs with independent observations. We use MetOp-A/Infrared Atmospheric Sounding Interferometer (IASI) CO retrievals and Measurement of OZone, water vapor, carbon monoxide, and nitrogen oxides by in-service AIrbus airCraft (MOZAIC) in situ CO profiles for our independent observation comparisons. Generally, the results confirm that assimilation of MOPITT CPSRs improves the Weather Research and Forecasting model with chemistry coupled to the ensemble Kalman filter data assimilation from the Data Assimilation Research Testbed (WRF-Chem/DART) analysis fit and forecast skill at a reduced computational cost compared to assimilation of raw retrievals. Comparison with the independent observations shows that assimilation of MOPITT CO generally improved the analysis fit and forecast skill in the lower troposphere but degraded it in the upper troposphere. We attribute that degradation to assimilation of MOPITT CO retrievals with a possible bias of  ∼ 14&thinsp;% above 300&thinsp;hPa. To discard the biased retrievals, in this paper, we also extend CPSRs to assimilation of truncated retrieval profiles (as opposed to assimilation of full retrieval profiles). Those results show that not assimilating the biased retrievals (i) resolves the upper tropospheric analysis fit degradation issue and (ii) reduces the impact of assimilating the remaining unbiased retrievals because the total information content and vertical sensitivities are changed.</p

Patients’ perspective regarding therapeutic footwear : an interpretative phenomenological approach

Aim: To explore patient perspectives’ with regards to the use of prescribed diabetic stock footwear. Methods: An exploratory qualitative design method using an Interpretative Phenomenological Analysis (IPA) was employed in this research. This specific branch of phenomenology was used to explore the perception of patients living with Type 2 diabetes Mellitus in relation to the use of their prescribed diabetic stock footwear. Twelve participants were recruited and in-depth, semi-structured interviews were conducted, recorded, transcribed and later analysed. Footwearpeer-reviewe

Stigma narratives: LGBT transitions and identities in Malta

This article is available open access through the publisher’s website at the link below. Copyright @ 2011 A B Academic Publishers.This article considers narratives of transition experiences of a group of Lesbian, Gay, Bisexual and Transgender (LGBT) young people in Malta. The article draws on Goffman's concept of stigma and uses this to explore transitions in a society that retains some traditional characteristics, particularly the code of honour and shame, although mediated by aspects of modernity. Interviews were undertaken with 15 young people with the goal of producing narratives. The article analyses the experience of stigma, its effects and how young people manage its consequences. It concludes by drawing attention to the pervasive nature of stigma and the importance of structure, agency and reflexivity in youth transitions. In particular stigma remains an important feature of societies in which hetero-normative sexuality remains dominant

A 12-week exercise programme has a positive effect on everyday executive function in young people with Down syndrome: a pilot non-randomised controlled trial

Background: Exercise has the potential to reduce cognitive decline in people with Down syndrome by maximising their cognitive function. The aim of the study was to determine the effect of regular exercise on cognitive functioning in young people with Down syndrome. Method: People with Down syndrome were eligible if aged between 13 and 35 years and enrolled to participate in an exercise programme (called FitSkills). The intervention was a 12-week community-based exercise programme completed with a student mentor. Outcomes were assessed before (week 0) and immediately after (week 13) the intervention. Executive functioning (planning, response inhibition, attention shifting) was assessed using Tower of London, Sustained Attention to Response Task, CANTAB Intra-extra Dimensional Set Shift Test, Cognitive Scale for Down Syndrome, and Behaviour Rating Inventory of Executive Function (BRIEF). Working memory was assessed using the CANTAB Paired Associates Learning task, and information processing speed was assessed using the Motor Screening Task. Outcomes were analysed using ANCOVA with the baseline measure as the covariate. Results: Twenty participants (9 women; mean age 23.6 ± 6.6 years) enrolled. Between-group differences, in favour of the experimental group, were found for the global executive composite score of the BRIEF (mean difference −4.77 units, 95% CI −9.30 to −0.25). There were no between group differences for any other outcome measured. Conclusion: Participation in a 12-week exercise programme was effective in improving everyday executive functions in young people with Down syndrome. These preliminary findings need to be confirmed in future randomised controlled trials of community-based exercise with larger sample sizes