76 research outputs found
The phase shift of line solitons for the KP-II equation
The KP-II equation was derived by [B. B. Kadomtsev and V. I.
Petviashvili,Sov. Phys. Dokl. vol.15 (1970), 539-541] to explain stability of
line solitary waves of shallow water. Stability of line solitons has been
proved by [T. Mizumachi, Mem. of vol. 238 (2015), no.1125] and [T. Mizumachi,
Proc. Roy. Soc. Edinburgh Sect. A. vol.148 (2018), 149--198]. It turns out the
local phase shift of modulating line solitons are not uniform in the transverse
direction. In this paper, we obtain the -bound for the local phase
shift of modulating line solitons for polynomially localized perturbations
Description of the inelastic collision of two solitary waves for the BBM equation
We prove that the collision of two solitary waves of the BBM equation is
inelastic but almost elastic in the case where one solitary wave is small in
the energy space. We show precise estimates of the nonzero residue due to the
collision. Moreover, we give a precise description of the collision phenomenon
(change of size of the solitary waves).Comment: submitted for publication. Corrected typo in Theorem 1.
Long time dynamics and coherent states in nonlinear wave equations
We discuss recent progress in finding all coherent states supported by
nonlinear wave equations, their stability and the long time behavior of nearby
solutions.Comment: bases on the authors presentation at 2015 AMMCS-CAIMS Congress, to
appear in Fields Institute Communications: Advances in Applied Mathematics,
Modeling, and Computational Science 201
Final Report of the Muon E821 Anomalous Magnetic Moment Measurement at BNL
We present the final report from a series of precision measurements of the
muon anomalous magnetic moment, a_mu = (g-2)/2. The details of the experimental
method, apparatus, data taking, and analysis are summarized. Data obtained at
Brookhaven National Laboratory, using nearly equal samples of positive and
negative muons, were used to deduce a_mu(Expt) = 11 659 208.0(5.4)(3.3) x
10^-10, where the statistical and systematic uncertainties are given,
respectively. The combined uncertainty of 0.54 ppm represents a 14-fold
improvement compared to previous measurements at CERN. The standard model value
for a_mu includes contributions from virtual QED, weak, and hadronic processes.
While the QED processes account for most of the anomaly, the largest
theoretical uncertainty, ~0.55 ppm, is associated with first-order hadronic
vacuum polarization. Present standard model evaluations, based on e+e- hadronic
cross sections, lie 2.2 - 2.7 standard deviations below the experimental
result.Comment: Summary paper of E821 Collaboration measurements of the muon
anomalous magnetic moment, each reported earlier in Letters or Brief Reports;
96 pages, 41 figures, 16 tables. Revised version submitted to PR
Search for Lorentz and CPT Violation Effects in Muon Spin Precession
The spin precession frequency of muons stored in the storage ring has
been analyzed for evidence of Lorentz and CPT violation. Two Lorentz and CPT
violation signatures were searched for: a nonzero
(=); and a sidereal variation of
. No significant effect is found, and the following
limits on the standard-model extension parameters are obtained: GeV; GeV; and the 95% confidence level limits
GeV and
GeV.Comment: 5 pages, 3 figures, submitted to Physical Review Letters, Modified to
answer the referees suggestion
An Improved Limit on the Muon Electric Dipole Moment
Three independent searches for an electric dipole moment (EDM) of the
positive and negative muons have been performed, using spin precession data
from the muon g-2 storage ring at Brookhaven National Laboratory. Details on
the experimental apparatus and the three analyses are presented. Since the
individual results on the positive and negative muon, as well as the combined
result, d=-0.1(0.9)E-19 e-cm, are all consistent with zero, we set a new muon
EDM limit, |d| < 1.9E-19 e-cm (95% C.L.). This represents a factor of 5
improvement over the previous best limit on the muon EDM.Comment: 19 pages, 15 figures, 7 table
Search for Lorentz and CPT Violation Effects in Muon Spin Precession
The spin precession frequency of muons stored in the storage ring has
been analyzed for evidence of Lorentz and CPT violation. Two Lorentz and CPT
violation signatures were searched for: a nonzero
(=); and a sidereal variation of
. No significant effect is found, and the following
limits on the standard-model extension parameters are obtained: GeV; GeV; and the 95% confidence level limits
GeV and
GeV.Comment: 5 pages, 3 figures, submitted to Physical Review Letters, Modified to
answer the referees suggestion
Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial
Background: The EMPA KIDNEY trial showed that empagliflozin reduced the risk of the primary composite outcome of kidney disease progression or cardiovascular death in patients with chronic kidney disease mainly through slowing progression. We aimed to assess how effects of empagliflozin might differ by primary kidney disease across its broad population. Methods: EMPA-KIDNEY, a randomised, controlled, phase 3 trial, was conducted at 241 centres in eight countries (Canada, China, Germany, Italy, Japan, Malaysia, the UK, and the USA). Patients were eligible if their estimated glomerular filtration rate (eGFR) was 20 to less than 45 mL/min per 1·73 m2, or 45 to less than 90 mL/min per 1·73 m2 with a urinary albumin-to-creatinine ratio (uACR) of 200 mg/g or higher at screening. They were randomly assigned (1:1) to 10 mg oral empagliflozin once daily or matching placebo. Effects on kidney disease progression (defined as a sustained ≥40% eGFR decline from randomisation, end-stage kidney disease, a sustained eGFR below 10 mL/min per 1·73 m2, or death from kidney failure) were assessed using prespecified Cox models, and eGFR slope analyses used shared parameter models. Subgroup comparisons were performed by including relevant interaction terms in models. EMPA-KIDNEY is registered with ClinicalTrials.gov, NCT03594110. Findings: Between May 15, 2019, and April 16, 2021, 6609 participants were randomly assigned and followed up for a median of 2·0 years (IQR 1·5–2·4). Prespecified subgroupings by primary kidney disease included 2057 (31·1%) participants with diabetic kidney disease, 1669 (25·3%) with glomerular disease, 1445 (21·9%) with hypertensive or renovascular disease, and 1438 (21·8%) with other or unknown causes. Kidney disease progression occurred in 384 (11·6%) of 3304 patients in the empagliflozin group and 504 (15·2%) of 3305 patients in the placebo group (hazard ratio 0·71 [95% CI 0·62–0·81]), with no evidence that the relative effect size varied significantly by primary kidney disease (pheterogeneity=0·62). The between-group difference in chronic eGFR slopes (ie, from 2 months to final follow-up) was 1·37 mL/min per 1·73 m2 per year (95% CI 1·16–1·59), representing a 50% (42–58) reduction in the rate of chronic eGFR decline. This relative effect of empagliflozin on chronic eGFR slope was similar in analyses by different primary kidney diseases, including in explorations by type of glomerular disease and diabetes (p values for heterogeneity all >0·1). Interpretation: In a broad range of patients with chronic kidney disease at risk of progression, including a wide range of non-diabetic causes of chronic kidney disease, empagliflozin reduced risk of kidney disease progression. Relative effect sizes were broadly similar irrespective of the cause of primary kidney disease, suggesting that SGLT2 inhibitors should be part of a standard of care to minimise risk of kidney failure in chronic kidney disease. Funding: Boehringer Ingelheim, Eli Lilly, and UK Medical Research Council
Parathyroid hormone-related protein serves as a prognostic indicator in oral squamous cell carcinoma
Pharmacometabolomics of docetaxel-treated human MCF7 breast cancer cells provides evidence of varying cellular responses at high and low doses
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