11 research outputs found

    Azimuthal anisotropy in S+Au reactions at 200 A GeV

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    Azimuthal correlations of photons produced at mid-rapidity in 200 A GeV S + Au collisions have been studied using a preshower photon multiplicity detector in the WA93 experiment. The Fourier expansion method has been employed to estimate the event plane via the anisotropy of the event as a function of centrality. The event plane correlation technique has been used to determine the true event anisotropy, beyond the anisotropy which arises due to finite multiplicity. The VENUS event generator with rescattering and proper simulation of the detector response can explain only a portion of the observed anisotropy. The residual anisotropy is found to be of the order of 5% for semi-central collisions. This suggests that directed collective flow of the produced particles is present at SPS energies. (C) 1997 Published by Elsevier Science B.V

    Genetics of chloroquine-resistant malaria: a haplotypic view

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    Sequence analysis of coding DNA fragments of pfcrt and pfmdr-1 genes in Plasmodium falciparum isolates from Odisha, India

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    The global emergence and spread of malaria parasites resistant to antimalarial drugs is the major problem in malaria control. The genetic basis of the parasite's resistance to the antimalarial drug chloroquine (CQ) is well-documented, allowing for the analysis of field isolates of malaria parasites to address evolutionary questions concerning the origin and spread of CQ-resistance. Here, we present DNA sequence analyses of both the second exon of the Plasmodium falciparum CQ-resistance transporter (pfcrt) gene and the 5' end of the P. falciparum multidrug-resistance 1 (pfmdr-1) gene in 40 P. falciparum field isolates collected from eight different localities of Odisha, India. First, we genotyped the samples for the pfcrt K76T and pfmdr-1 N86Y mutations in these two genes, which are the mutations primarily implicated in CQ-resistance. We further analyzed amino acid changes in codons 72-76 of the pfcrt haplotypes. Interestingly, both the K76T and N86Y mutations were found to co-exist in 32 out of the total 40 isolates, which were of either the CVIET or SVMNT haplotype, while the remaining eight isolates were of the CVMNK haplotype. In total, eight nonsynonymous single nucleotide polymorphisms (SNPs) were observed, six in the pfcrt gene and two in the pfmdr-1 gene. One poorly studied SNP in the pfcrt gene (A97T) was found at a high frequency in many P. falciparum samples. Using population genetics to analyze these two gene fragments, we revealed comparatively higher nucleotide diversity in the pfcrt gene than in the pfmdr-1 gene. Furthermore, linkage disequilibrium was found to be tight between closely spaced SNPs of the pfcrt gene. Finally, both the pfcrt and the pfmdr-1 genes were found to evolve under the standard neutral model of molecular evolution

    A Measurement of the holographic minimum observable beam branching ratio in the Fermilab 15-foot bubble chamber

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    Holography has been used successfully in combination with conventional optics for the first time in a large cryogenic bubble chamber, the 15-Foot Bubble Chamber at Fermilab, during a physics run. The innovative system combined the reference beam with the object beam, illuminating a conical volume of 1.4\sim 1.4~m3^3. Bubble tracks from neutrino interactions with a width of 120  μ\sim 120\;\mum have been recorded with good contrast. The ratio of intensities of the object light to the reference light striking the film is called the Beam Branching Ratio. We obtained in our experiment an exceedingly small minimum-observable ratio of (0.54±0.21)×107(0.54 \pm 0.21) \times 10^{-7}. The technology has the potential for a wide range of applications

    COHERENT PRODUCTION OF pi+ pi- MESONS BY CHARGED CURRENT INTERACTIONS OF NEUTRINOS AND ANTI-NEUTRINOS ON NEON NUCLEI AT THE TEVATRON

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    Coherent single-pion production on neon nuclei is studied using the Fermilab 15-ft bubble chamber filled with a heavy Ne-H2 mixture and exposed to the Tevatron neutrino beam. In the neutrino energy range 40ε300 GeV, the net signal is 20±6 events, giving a corrected rate per charged-current event of (0.26±0.10)%. The cross section and kinematic distributions agree with the predictions of a model based on partial conservation of axial-vector current and meson dominance. © 1989 The American Physical Society.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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