536 research outputs found

    From Insularity to Islandness: The use of place branding to achieve sustainable island tourism

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    This paper aims to outline the role that place branding plays in shaping a new framework for sustainable island tourism. Islandness, as a contemporary context, underlines that islands share a set of unique features and they need to be studied on their own terms; they combine elements of urban and rural regions at the same time. Place branding is evolving as a crucial element for differentiated marketing that conditionally can also form an alternative tool to achieve sustainability for island regions. Therefore, policy makers need to examine tourism policies for island regions through the lenses of Nissology. It is commonly accepted that globalisation has intensified the competition between countries, cities and regions to attract investment, high quality human capital, various potential audiences and visitors. Several factors play a significant role in shaping the context in which places develop nowadays: climate change, new technologies, tourism pressures are just a few to highlight from the public discussion and academic debates. A growing number of researchers argue that place branding could be the strategic planning procedure needed, able to achieve multifaceted sustainability of an island destination. One very important issue raised often by both academics and practitioners is the role of stakeholders and local governance in such strategic processes like sustainable tourism development of a destination. The literature review, in this paper, explores why islandness and place branding have become significant for islands’ sustainable tourism development. Therefore, building on existing cross-discipline theoretical foundations, the present paper aims to (a) highlight the link between islandness and contemporary place branding, (b) emphasise the need to establish the term ‘island branding’, and (c) suggest a potential framework deriving from this linkage as a proper solution for contributing to the next era of sustainable tourism development for island regions

    Life-Cycle Cost Model and Design Optimization of Base-Isolated Building Structures

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    Design of economic structures adequately resistant to withstand during their service life, without catastrophic failures, all possible loading conditions and to absorb the induced seismic energy in a controlled fashion, has been the subject of intensive research so far. Modern buildings usually contain extremely sensitive and costly equipment that are vital in business, commerce, education and/or health care. The building contents frequently are more valuable than the buildings them-selves. Furthermore, hospitals, communication and emergency centres, police and fire stations must be operational when needed most: immediately after an earthquake. Conventional con-struction can cause very high floor accelerations in stiff buildings and large interstorey drifts in flexible structures. These two factors cause difficulties in insuring the safety of both building and its contents. For this reason base-isolated structures are considered as an efficient alternative design practice to the conventional fixed-base one. In this study a systematic assessment of op-timized fixed and base-isolated reinforced concrete buildings is presented in terms of their initial and total cost taking into account the life-cycle cost of the structures

    Relevance of pharmacogenomics for developing countries in Europe : implementation in the Maltese population

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    Pharmacogenomics is a promising new discipline that can realize personalized treatment for patients suffering from many common diseases, particularly those with multiple treatment modalities. Recent advances in the deciphering of the human genome sequence and high throughput genotyping technology have led to the reduction of the overall genotyping costs and enabled the inclusion of genotype-related dosing recommendations into drug package inserts, hence allowing the integration of pharmacogenomics into clinical practice. Although, pharmacogenomics gradually assumes an integral part in mainstream medical practice in developed countries, many countries, particularly from the developing world, still do not have access either to the knowledge or the resources to individualize drug treatment. The PharmacoGenetics for Every Nation Initiative (PGENI) aims to fill in this gap, by making pharmacogenomics globally applicable, not only by defining population-specific pharmacogenomic marker frequency profiles and formulating country-specific recommendations for drug efficacy and safety but also by increasing general public and healthcare professionals’ awareness over pharmacogenomics and genomic medicine. This article highlights the PGENI activities in Europe and its implementation in the Maltese population, in an effort to make pharmacogenomics readily applicable in European healthcare systems.peer-reviewe
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