Hybrid Constructions of Binary Sequences With Low Autocorrelation Sideobes

In this work, a classical problem of the digital sequence design, or more precisely, finding binary sequences with optimal peak sidelobe level (PSL), is revisited. By combining some of our previous works, together with some mathematical insights, few hybrid heuristic algorithms were created. During our experiments, and by using the aforementioned algorithms, we were able to find PSL-optimal binary sequences for all those lengths, which were previously found during exhaustive searches by various papers throughout the literature. Then, by using a general-purpose computer, we further demonstrate the effectiveness of the proposed algorithms by revealing binary sequences with lengths between 106 and 300, the majority of which possess record-breaking PSL values. Then, by using some well-known algebraic constructions, we outline few strategies for finding highly competitive binary sequences, which could be efficiently optimized, in terms of PSL, by the proposed algorithms

Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking

Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 adapter FEZ1 are enriched for presynaptic components and identify that specific phosphorylation of FEZ1 at its serine 58 regulatory site is mediated by microtubule affinity-regulating kinases (MARK/PAR-1). Loss of MARK/PAR-1 impairs axonal transport, with adapter and cargo abnormally co-aggregating in neuronal cell bodies and axons. Presynaptic specializations are markedly reduced and distorted in FEZ1 and MARK/PAR-1 mutants. Strikingly, abnormal co-aggregates of unphosphorylated FEZ1, Kinesin-1 and its putative cargoes are present in brains of transgenic mice modelling aspects of Alzheimer's disease, a neurodegenerative disorder exhibiting impaired axonal transport and altered MARK activity. Our findings suggest that perturbed FEZ1-mediated synaptic delivery of proteins arising from abnormal signalling potentially contributes to the process of neurodegeneration

Essays on Simultaneous Innovation and Macroeconomics

This dissertation consists of three essays which explore the impact of simultaneous innovation on growth, macroeconomic fluctuations, and welfare, as well as their implications for the patent system. Chapter one provides an overview. Chapter two analyses the impact of the coordination frictions implicit in the presence of simultaneous innovation on growth and welfare. The coordination failure generates a mass of foregone innovation and reduces the economy-wide research intensity. Both effects decrease the growth rate. Because of this, the frictions also amplify the fraction of wasteful simultaneous innovation. A calibration suggests the impact of coordination frictions on the growth rate and welfare is substantial.Chapter three studies the impact of simultaneous innovation on macroeconomic fluctuations in a stochastic expanding-variety endogenous growth model. Research projects innovated by many firms simultaneously are of higher quality, on average, and contribute relatively more to the expansion of the knowledge stock in the economy. This delivers an endogenous mechanism that amplifies the volatility of R&D investment by a factor of two. Furthermore, due to this endogenous mechanism, the model produces mildly pro-cyclical R&D --- a well-documented feature of the data. Whereas the existing literature has proposed several mechanisms that explain the positive correlation between investment in R&D and output, the moderate strength of the relationship has remained under-explored.The conventional viewpoint on the patent system is that it allocates market power in order to stimulate disclosure of information and create incentives for firms to innovate. Chapter four develops a dynamic equilibrium search model to show that, in sharp contrast to this traditional view, the patent system can erode, rather than allocate market power. This result is obtained, regardless of whether or not it provides prior user rights, by incentivizing firms to patent and, at the same time, delivering a sufficiently weak patent protection. The patent system delivers incentives by either punishing firms that choose not to patent or by providing a strategic advantage to firms that patent. Analysis of the welfare properties of the patent system suggests its ability to erode market power may be central to its capability to increase welfare

MARKET ENTRY STRATEGIES TO EMERGING MARKETS: A CONCEPTUAL MODEL OF TURNKEY PROJECT DEVELOPMENT

The main purpose of the paper is to analyse the international market entry strategies in the light of globalisation processes and to propose a conceptual model of turnkey projects as market entry mode. The specific research objectives are as follows: 1. to develop an integrated framework of the turnkey marketing process as a conceptual model; 2. to analyse BRICS countries as potential host countries for turnkey projects implementation; 3. to assess potential implications of proposed conceptual model for global market entry decisions

Bistra Vassileva_a_Polazni.qxd

Abstract The main purpose of the paper is to analyse the international market entry strategies in the light of globalisation processes and to propose a conceptual model of turnkey projects as market entry mode. The specific research objectives are as follows: 1. to develop an integrated framework of the turnkey marketing process as a conceptual model; 2. to analyse BRICS countries as potential host countries for turnkey projects implementation; 3. to assess potential implications of proposed conceptual model for global market entry decisions

Stan i trendy w rozwoju systemu logistycznego Bułgarskich Sił Zbrojnych

Artykuł omawia transformację systemu logistycznego bułgarskiej armii począwszy od zmian w 1991 roku, przedstawiając historyczną analizę rozwoju tego systemu. Opierając się na podejściu systemowym, autor opisuje reformy, które zostały wdrożone w zarządzającym oraz wykonawczym podsystemie logistycznego systemu Bułgarskich Sił Zbrojnych oraz prezentuje obecny stan rozwoju tego systemu. Koncentrując się na działaniach związanych ze wsparciem udzielanym przez państwa-gospodarzy, autor prezentuje udoskonalenia struktur logistycznych na trzech poziomach rządzenia oraz działania jednostek logistycznych mające na celu realizacje zadań w formatach zarówno narodowym, jak i koalicyjnym

Wybrane aspekty trenowania personelu logistycznego w regionalnym ośrodku logistycznym w Akademii Wojskowej im. Georgi Rakovskiego w Bułgarii

Artykuł opisuje tworzenie Regionalnego Ośrodka Logistycznego w Akademii Wojskowej im. Georgi Rakovskiego w Bułgarii, które odbywało się przy wsparciu Francji. Autor analizuje kształcenie personelu logistycznego koncentrując się na omówieniu celów i zadań. Artykuł ukazuje istotę metodologii nauczania przyjętej w Regionalnym Ośrodku Logistycznym, opisuje na czym polegają ćwiczenia oraz prezentuje osiągnięcia kwalifikacyjne personelu