SAŽETA POVIJEST SUDSKE MEDICINE U ČEŠKOJ REPUBLICI

This paper presents the most important historical facts about all forensic medicine workplaces in the Czech Republic since the beginning till present day, including a perspective on how to establish a new one. Each of the University Forensic Medicine Institutes or district Departments is covered by at least one author. The oldest institute is in Prague and in Brno, the youngest is in Pardubice.U radu su ukratko navedeni najvažniji podaci o povijesti svih medicinskih odjela za sudsku medicinu u Češkoj Republici od samih početaka pa do današnjice, uključujući perspektivu i mogućnosti za osnivanje novih. Svaki od sveučilišnih instituta i okružnih odjela zastupa minimalno jedan autor. Najstarija povijest sudske medicine je naravno u Pragu i u Brnu. Najmlađi odjel je u Pardubicama

OXI1 and DAD Regulate Light-Induced Cell Death Antagonistically through Jasmonate and Salicylate Levels

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Involvement of MAP kinase SIMK and actin cytoskeleton in the regulation of root hair tip growth.

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Involvement of the mitogen-activated protein kinase SIMK in regulation of root hair tip growth

Mitogen-activated protein kinases (MAPKs) are involved in stress signaling to the actin cytoskeleton in yeast and animals. We have analyzed the function of the stress-activated alfalfa MAP kinase SIMK in root hairs. In epidermal cells, SIMK is predominantly nuclear. During root hair formation, SIMK was activated and redistributed from the nucleus into growing tips of root hairs possessing dense F-actin meshworks. Actin depolymerization by latrunculin B resulted in SIMK relocation to the nucleus. Conversely, upon actin stabilization with jasplakinolide, SIMK co-localized with thick actin cables in the cytoplasm. Importantly, latrunculin B and jasplakinolide were both found to activate SIMK in a root-derived cell culture. Loss of tip-focused SIMK and actin was induced by the MAPK kinase inhibitor UO 126 and resulted in aberrant root hairs. UO 126 inhibited targeted vesicle trafficking and polarized growth of root hairs. In contrast, overexpression of gain-of-function SIMK induced rapid tip growth of root hairs and could bypass growth inhibition by UO 126. These data indicate that SIMK plays a crucial role in root hair tip growth

Involvement of MAP kinase SIMK and actin cytoskeleton in the regulation of root hair tip growth.

International audienc