Representações sociais de residentes multiprofissionais acerca da idealização davivência na rede de atenção à saúde / Social representations of multiprofessional residents about idealization of life in the health care network

Este artigo tem como objetivo apresentar a percepção de residentes multiprofissionais em saúde acerca da vivência prática na Rede de Atenção à Saúde, à luz da teoria das representações sociais. Trata-se de um estudo qualitativo, descritivo-exploratório, desenvolvido no Hospital Universitário Regional dos Campos Gerais no ano de 2019. Considerou-se como população de estudo os residentes multiprofissionais em saúde (n=55), em seu primeiro ano de residência. Para a coleta de dados utilizou-se o Grupo Focal; e a pergunta norteadora única: ‘Qual importância você atribui à vivência prática na Rede de Atenção à Saúde? Por favor, expresse todas as suas opiniões’. Os dados foram analisados por meio do discurso do sujeito coletivo e à luz das Representações Sociais. Os resultados possibilitaram a extração da temática “Conhecimento do fluxo da rede de atenção à saúde” a qual emergiu quatro ideias centrais com seus respectivos discursos. A primeira ideia central discorre a potencialidade de contextualização teórico-prática angariada com a vivência prática nos diferentes níveis de atenção da rede. Além de propiciar o entendimento acerca do funcionamento da rede, permite potencializar o processo de trabalho dos residentes, garantindo encaminhamento correto do paciente na rede, maior resolubilidade e acolhimento diferenciado do cuidado em saúde, conforme observado nas ideias centrais subsequentes.  Ademais, os residentes expressaram a representação social inerente a maior valorização do SUS. Conclui-se que a representação social dos residentes multiprofissionais em saúde acerca da vivência na rede de atenção à saúde é enriquecedora, geradora de crescimento profissional e apropriação de conhecimentos científicos e ideológicos. 

Participation Of Prolactin Receptors And Phosphatidylinositol 3-kinase And Map Kinase Pathways In The Increase In Pancreatic Islet Mass And Sensitivity To Glucose During Pregnancy.

Prolactin (PRL) exerts its biological effects mainly by activating the Janus kinase/signal transducer and activator of transcription 5 (JAK/STAT5) signaling pathway. We have recently demonstrated that PRL also stimulates the insulin receptor substrates/phosphatidylinositol 3-kinase (IRSs/PI3K) and SH2-plekstrin homology domain (SHC)/ERK pathways in islets of neonatal rats. In the present study, we investigated the involvement of the PI3K and MAP kinase (MAPK) cascades in islet development and growth in pregnant rats. The protein expression of AKT1, p70S6K and SHC was higher in islets from pregnant compared with control rats. Higher basal levels of tyrosine phosphorylation were found in classic transducers of insulin cell signaling (IRS1, IRS2 and SHC). Increased levels of threonine/tyrosine phosphorylation of ERK1/2 and serine phosphorylation of AKT and p70S6K were also detected. To assess the participation of PRL in these phenomena, pregnant and control rats were treated with an antisense oligonucleotide to reduce the expression of the PRL receptor (PRLR). Phosphorylation of AKT was reduced in islets from pregnant and control rats, whereas p70S6K protein levels were reduced only in islets from treated pregnant rats. Finally, glucose-induced insulin secretion was reduced in islets from pregnant but not from control rats treated with the PRLR antisense oligonucleotide. In conclusion, downstream proteins of the PI3K (AKT and p70S6K) and MAPK (SHC and ERK1/2) cascades are regulated by PRL signaling in islets from pregnant rats. These findings indicate that these pathways participate in the increase in islet mass and the sensitivity to glucose during pregnancy.183469-7

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora