1 research outputs found
Escritura p煤blica de declaraci贸n de [...] de localidades, [...] de esta y del Convenio con los accionistas otorgada por la Comisi贸n Directiva del Teatre del Liceo y reglamento de mismo ante Francisco Javier Moreu, notario, 31 de marzo de 1851
A new triterpenoid, urmiensolide
(<b>1</b>), was isolated
from <i>Salvia urmiensis</i>. The structure was elucidated
by a combination of 1D and 2D NMR, HRESIMS, and X-ray crystallographic
analyses. The absolute configuration was established by comparison
of experimental and simulated ECD spectra. Urmiensolide is the first
pentacyclic triterpenoid bearing a 蔚-lactone E-ring. The compound
showed in vitro antitrypanosoal activity with an IC<sub>50</sub> value
of 5.6 渭M against the <i>Trypanosoma brucei rhodesiense</i> STIB 900 strain and a selectivity index of 33. A possible biosynthetic
pathway of <b>1</b> from 伪-amyrin is proposed