2,026 research outputs found
Effect of microstructural change on magnetic property of Mn-implanted p-type GaN
The Mn ions were implanted into p-type GaN and annealed to achieve a dilute magnetic semiconductor. The ferromagnetic property was obtained and attributed to the formation of Ga-Mn magnetic phases. The ferromagnetic signal was reduced and antiferromagnetic Mn-N compounds were produced at higher temperature annealing at 900 ??C. Results showed that N vacancies play a crucial role in weakening the ferromagnetic property in the Mn-implanted GaN.open586
A universal characterization of nonlinear self-oscillation and chaos in various particle-wave-wall interactions
The comprehensive parameter space of self-oscillation and its period-doubling route to chaos are shown for bounded beam-plasma systems. In this parametrization, it is helpful to use a potentially universal parameter in close analogy with free-electron-laser chaos. A common parameter, which is related to the velocity slippage and the ratio of bounce to oscillation frequencies, is shown to have similar significance for different physical systems. This single parameter replaces the dependences on many input parameters, thus suitable for a simplifying and diagnostic measure of nonlinear dynamical and chaotic phenomena for various systems of particle-wave interactions. The results of independent kinetic simulations verify those of nonlinear fluid simulations.open9
Additive Angular Margin for Few Shot Learning to Classify Clinical Endoscopy Images
Endoscopy is a widely used imaging modality to diagnose and treat diseases in
hollow organs as for example the gastrointestinal tract, the kidney and the
liver. However, due to varied modalities and use of different imaging protocols
at various clinical centers impose significant challenges when generalising
deep learning models. Moreover, the assembly of large datasets from different
clinical centers can introduce a huge label bias that renders any learnt model
unusable. Also, when using new modality or presence of images with rare
patterns, a bulk amount of similar image data and their corresponding labels
are required for training these models. In this work, we propose to use a
few-shot learning approach that requires less training data and can be used to
predict label classes of test samples from an unseen dataset. We propose a
novel additive angular margin metric in the framework of prototypical network
in few-shot learning setting. We compare our approach to the several
established methods on a large cohort of multi-center, multi-organ, and
multi-modal endoscopy data. The proposed algorithm outperforms existing
state-of-the-art methods.Comment: 10 page
Engineered Protein Polymer-Gold Nanoparticle Hybrid Materials for Small Molecule Delivery
We have fabricated protein polymer-gold nanoparticle (P-GNP) nanocomposites that exhibit enhanced binding and delivery properties of the small hydrophobic molecule drug, curcumin, to the model breast cancer cell line, MCF-7. These hybrid biomaterials are constructed via in situ GNP templated-synthesis with genetically engineered histidine tags. The P-GNP nanocomposites exhibit enhanced small molecule loading, sustained release and increased uptake by MCF-7 cells. When compared to the proteins polymers alone, the P-GNPs demonstrate a greater than 7-fold increase in curcumin binding, a nearly 50% slower release profile and more than 2-fold increase in cellular uptake of curcumin. These results suggest that P-GNP nanocomposites serve as promising candidates for drug delivery vehicles
The ExoMolOP Database: Cross-sections and k-tables for Molecules of Interest in High-Temperature Exoplanet Atmospheres
A publicly available database of opacities for molecules of astrophysical interest, ExoMolOP, has been compiled for over 80 species, based on the latest line list data from the ExoMol, HITEMP and MoLLIST databases. These data are generally suitable for characterising high temperature exoplanet or cool stellar/substellar atmospheres, and have been computed at a variety of pressures and temperatures, with a few molecules included at room-temperature only from the HITRAN database. The data are formatted in different ways for four different exoplanet atmosphere retrieval codes; ARCiS, TauREx, NEMESIS and petitRADTRANS, and include both cross-sections (at R~=~λΔλ~=~15,000) and k-tables (at R~=~λΔλ~=~1000) for the 0.3~-~50μm wavelength region. Opacity files can be downloaded and used directly for these codes. Atomic data for alkali metals Na and K are also included, using data from the NIST database and the latest line shapes for the resonance lines. Broadening parameters have been taken from the literature where available, or from those for a known molecule with similar molecular properties where no broadening data are available
A systematic approach to performing a comprehensive transesophageal echocardiogram. A call to order
<p>Abstract</p> <p>Background</p> <p>While the order for a clinical transthoracic examination is fairly standardized, there is considerable variability between laboratories and even among physicians in the same laboratory with regard to the order for transesophageal echocardiograms (TEE). A systematic approach is desirable for more efficient use of physician and patient time, avoidance of inadvertent omission of important views, and to facilitate study review.</p> <p>Methods</p> <p>We propose a standardized approach to TEE data acquisition in which cardiac structures are systematically identified and characterized at sequential positions and imaging planes to facilitate organized, efficient and comprehensive assessment.</p> <p>Results</p> <p>Our approach to TEE study begins in the mid-esophagus with the imaging plane at 0°. Based on the specific indication for the TEE, a cardiac structure (e.g., mitral valve, left atrial appendage, or interatrial septum) is chosen as the primary focal point for a comprehensive, multiplane analysis. This structure is assessed in 20° – 30° increments as the imaging plane is advanced from 0° to 165°. Using the aortic valve as a reference point, pertinent cardiac structures are then assessed as the imaging plane is reduced to 135°, to 90°, to 40 – 60° and then back to 0°. The probe is then advanced into the stomach to obtain transgastric images at 0°, 90°, and 120°. Finally, the thoracic aorta and pulmonary artery are assessed as the probe is withdrawn from the body. Using this method, an organized and comprehensive TEE can be performed in 10 – 15 minutes.</p> <p>Conclusion</p> <p>A standardized and systematic TEE approach is described for efficient and comprehensive TEE study.</p
Factors associated with failed treatment : an analysis of 121,744 women embarking on their first IVF cycles
Peer reviewedPublisher PD
Striation mechanism and triggered striation in dielectric microdischarge plasma
The striation mechanism of dielectric microdischarges, as in many plasma devices, is extensively explored by collisional kinetic and fluid simulations. Striation in a typical dielectric microdischarge device predominantly occurs near the anode region and is basically governed by the ionization-dominated ??-processes, wherein surface and space charges collectively dictate the phenomenon in a complex manner. A novel type of striation has been investigated by us near the cathode region, which is dominated by ??-processes and is driven by the secondary-electron emission mechanism.close101
Three-dimensional femtosecond laser nanolithography of crystals
Nanostructuring hard optical crystals has so far been exclusively feasible at
their surface, as stress induced crack formation and propagation has rendered
high precision volume processes ineffective. We show that the inner chemical
etching reactivity of a crystal can be enhanced at the nanoscale by more than
five orders of magnitude by means of direct laser writing. The process allows
to produce cm-scale arbitrary three-dimensional nanostructures with 100 nm
feature sizes inside large crystals in absence of brittle fracture. To showcase
the unique potential of the technique, we fabricate photonic structures such as
sub-wavelength diffraction gratings and nanostructured optical waveguides
capable of sustaining sub-wavelength propagating modes inside yttrium aluminum
garnet crystals. This technique could enable the transfer of concepts from
nanophotonics to the fields of solid state lasers and crystal optics.Comment: Submitted Manuscript and Supplementary Informatio
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