A thick shell Casimir effect

We consider the Casimir energy of a thick dielectric-diamagnetic shell under a uniform velocity light condition, as a function of the radii and the permeabilities. We show that there is a range of parameters in which the stress on the outer shell is inward, and a range where the stress on the outer shell is outward. We examine the possibility of obtaining an energetically stable configuration of a thick shell made of a material with a fixed volume

197 MHz Waveguide Loaded Crabbing Cavity Design for the Electron-Ion Collider

The Elec­tron-Ion Col­lider will re­quire crab­bing sys­tems at both hadron and elec­tron stor­age rings in order to reach the de­sired lu­mi­nos­ity goal. The 197 MHz crab cav­ity sys­tem is one of the crit­i­cal rf sys­tems of the collider. The crab cav­ity, based on the rf-di­pole de­sign, explores the op­tion of wave­guide load damp­ing to sup­press the higher order modes and meet the tight im­ped­ance spec­i­fi­ca­tions. The cav­ity is de­signed with com­pact dog-bone wave­guides with tran­si­tions to rec­tan­gu­lar wave-guides and wave­guide loads. This paper pre­sents the com­pact 197 MHz crab cav­ity de­sign with wave­guide damp­ing and other an­cil­lar­ies

Infrared Properties of QCD from Dyson-Schwinger equations

I review recent results on the infrared properties of QCD from Dyson-Schwinger equations. The topics include infrared exponents of one-particle irreducible Green's functions, the fixed point behaviour of the running coupling at zero momentum, the pattern of dynamical quark mass generation and properties of light mesons.Comment: 47 pages, 19 figures, Topical Review to be published in J.Phys.G, v2: typos corrected and some references adde

Maternal LAMP/p55gagHIV-1 DNA Immunization Induces In Utero Priming and a Long-Lasting Immune Response in Vaccinated Neonates

Infants born to HIV-infected mothers are at high risk of becoming infected during gestation or the breastfeeding period. A search is thus warranted for vaccine formulations that will prevent mother-to-child HIV transmission. The LAMP/gag DNA chimeric vaccine encodes the HIV-1 p55gag fused to the lysosome-associated membrane protein-1 (LAMP-1) and has been shown to enhance anti-Gag antibody (Ab) and cellular immune responses in adult and neonatal mice; such a vaccine represents a new concept in antigen presentation. In this study, we evaluated the effect of LAMP/gag DNA immunization on neonates either before conception or during pregnancy. LAMP/gag immunization of BALB/c mice before conception by the intradermal route led to the transfer of anti-Gag IgG1 Ab through the placenta and via breastfeeding. Furthermore, there were an increased percentage of CD4+CD25+Foxp3+T cells in the spleens of neonates. When offspring were immunized with LAMP/gag DNA, the anti-Gag Ab response and the Gag-specific IFN-γ-secreting cells were decreased. Inhibition of anti-Gag Ab production and cellular responses were not observed six months after immunization, indicating that maternal immunization did not interfere with the long-lasting memory response in offspring. Injection of purified IgG in conjunction with LAMP/gag DNA immunization decreased humoral and cytotoxic T-cell responses. LAMP/gag DNA immunization by intradermal injection prior to conception promoted the transfer of Ab, leading to a diminished response to Gag without interfering with the development of anti-Gag T- and B-cell memory. Finally, we assessed responses after one intravenous injection of LAMP/gag DNA during the last five days of pregnancy. The intravenous injection led to in utero immunization. In conclusion, DNA vaccine enconding LAMP-1 with Gag and other HIV-1 antigens should be considered in the development of a protective vaccine for the maternal/fetal and newborn periods