Effect of acute experimental aluminum poisoning on hematologic parameters

Having in mind the presence of aluminum in industry, as well as in households, we wanted to define changes in the number of erythrocytes and aluminum content in the plasma and erythrocytes following acute aluminum poisoning under experimental conditions. The experiment involved gerbils which received intraperitoneally aluminum chloride solution at a dose of 3.7g per kg of body mass. The experimental group was sacrificed after 24, 48, 72 and 96 hours from the beginning of the experiment by cardiac punction or by abdominal artery punction. The control group was treated with saline, only. The number of erythrocytes and hemoglobin concentration were considerably reduced with respect to the control group, most likely as the result of cell membrane changes and reduced life cycle of erythrocytes. During the experiment, aluminum content in the plasma was increased in the first and second day of the experiment, it started to decline on the third day, while on the fourth day it returned to its original value, which proves again the existence of a special mechanism of "clearance" of aluminum in plasma

Meron ground states of quantum Hall droplets

We argue that topological meron excitations, which are in a strong coupling phase (bound in pairs) in infinite quantum Hall ferromagnets, become deconfined in finite size quantum Hall systems. Although effectively for larger systems meron energy grows with the size of the system, when gyromagnetic ratio is small meron becomes the lowest lying state of a quantum Hall droplet. This comes as a consequence of the many-body correlations built in the meron construction that minimize the interaction energy. We demonstrate this by using mean field ansatzes for meron wave function. The ansatzes will enable us to consider much larger system sizes than in the previous work [A. Petkovic and M.V. Milovanovic, PRL 98, 066808 (2007)], where fractionalization into merons was introduced.Comment: 6 pages, 6 figure

Dipole representation of half-filled Landau level

We introduce a variant of dipole representation for composite fermions in a half-filled Landau level, taking into account the symmetry under exchange of particles and holes. This is implemented by a special constraint on composite fermion and composite hole degree of freedom (of an enlarged space), that makes the resulting composite particle, dipole, a symmetric object. We study an effective Hamiltonian, that commutes with the constraint on the physical space, and fulfills the requirement for boost invariance on the Fermi level. The calculated Fermi liquid parameter F2 is in a good agreement with numerical investigations in [Phys. Rev. Lett. 121, 147601 (2018)].Comment: 9 pages, 4 figure

Tunneling-driven breakdown of the 331 state and the emergent Pfaffian and composite Fermi liquid phases

We examine the possibility of creating the Moore-Read Pfaffian in the lowest Landau level when the multicomponent Halperin 331 state (believed to describe quantum Hall bilayers and wide quantum wells at the filling factor $\nu=1/2$) is destroyed by the increase of tunneling. Using exact diagonalization of the bilayer Hamiltonian with short-range and long-range (Coulomb) interactions in spherical and periodic rectangular geometries, we establish that tunneling is a perturbation that drives the 331 state into a compressible composite Fermi liquid, with the possibility for an intermediate critical state that possesses some properties of the Moore-Read Pfaffian. These results are interpreted in the two-component BCS model for Cauchy pairing with a tunneling constraint. We comment on the conditions to be imposed on a system with fluctuating density in order to achieve the stable Pfaffian phase.Comment: 10 pages, 7 figure

Estimation of rotary equipment integrity using fracture mechanics parameters

Integritet konstrukcija kao naučna i inženjerska disciplina kao deo mehanike loma obuhvata analizu stanja i dijagnostiku ponašanja i otkaza, procenu veka i revitalizaciju konstrukcija, kao što je poznato od ranije. Primenom metoda definisanih ovom naučnom disciplinom mogu se odrediti „slaba“ mesta u konstrukciji, pre nastanka prsline kao i u prisustvu prsline kod konstrukcija koje su izložene razlitičitim tipovima opterećenja. Procena integriteta rotacione opreme, kao što je vratilo turbine, predstavlja poseban izazov zbog prirode njegovog opterećenja. Kada se na u ceo problem doda i uticaj prsline problem postaje još složeniji i zahteva uključivanje više naučnih disciplina i alata, poput softverskih paketa kojima je moguće simulirati radne uslove opreme, tačnije, dinimačko opterećenje koje može izazvati zamor materijala. Tema ove doktorske disertacije je istraživanje ponašanja rotacione opreme, konkretno vratila turbine, Hidroelektrane „Đerdap II“ u prisustvu prslina sa ciljem određivanja integriteta i preostalog radnog veka vratila turbine. Opasnost u slučaju prisustvu prsline kod ovog tipa opreme je mogućnost pojave krtog loma koji je, po prirodi, nepredvidiv i često sa fatalnim posledicama. Posebna pažnja u ovoj studiji posvećena je mestima koja izazivaju koncentraciju napona. U rešavanju problema procene integriteta rotacione opreme vratila hidroelektrane korišćeni su softverski paketi Abaqus i MORFEO, odnosno principi proširene metode konačnih elemenata (eng. XFEM). Kao ulazni podaci u primeni XFEM metode primenom ovih paketa korišćeni si eksperimentalni rezultati primenom koncepta elasto-plastične mehanike loma kao i primena poznatog Parisovog zakona sa ciljem određivanja brzine rasta zamorne prsline. Dobijeni podaci eksperimentalnim ispitivanjima, konkretno vrednosti parametara C i m poznatog Parisovog zakona, poslužili su kao osnova za urađene numeričke simulacije rasta zamorne prsline u samom vratilu trubine primenom zakona linealno-elastične mehanike loma. Pored toga, u ovoj studiji urađena je naponska analiza vratila turbine kao i neposredno poređenje analitičkih i numeričkih rezultata. Osnovni cilj celokupne studije može se svesti na objašnjenje kompleksnog stanja i generalno ponašanje rotacione opreme, odnosno vratila turbine u prisustvu prslina nastalih zamornim opterećenjem i u prisustvu koncetratora napona. Može se istaći da je i akcenat ove studije utvrđivanje zavisnosti brzine rasta prsline od veličine prsline za određenu geometriju vratila na osnovu čije je moguće proceniti integritet i vek vratila, pored svih poznatih osobina materijala. Indirektno, razvijeni i predstavljeni numerički modeli u ovoj disertaciji, kao i eksperimentalne procedure koji imaju veliku primenljivost u oblasti procene integriteta generalno kod opreme ovog tipa takođe su imali za cilj davanje naučnom ivi inženjerskom doprinosu analize ove studije sa ciljem utvrđivanja integriteta i preostalog radnog veka opreme izložene zamarajućem opterećenju u prisustvu prsline.As it is known, structural integrity as a scientific and engineering discipline as part of fracture mechanics includes structure analysis, its behavior and failure diagnostics, life assessment as well as structural revitalization. By applying the methods defined by this scientific discipline, it is possible to determine "weak" places in the structure, before crack occure and in the presence of a crack in structures that are exposed to a different types of loads. Assessing the integrity of rotary equipment, such as turbine shafts, is a particular challenge due to the nature of its load. Presence the crack makes the whole problem becoming even more complex and requires the inclusion of more scientific disciplines and tools, such as software packages that can simulate the working conditions of equipment, more precisely, dynamic load that can cause material fatigue of the structure. The topic of this doctoral dissertation is the research of the behavior of rotary equipment, specifically turbine shafts, Hydroelectric Power Plant "Đerdap II" in the presence of cracks with the aim of determining the integrity and remaining service life of turbine shafts. The danger in the presence of a crack with this type of equipment is the possibility of a brittle fracture which is, by its nature, unpredictable, and often with fatal consequences. Special attention in this study is dedicated to the places on the structure that cause stress concentration. The Abaqus and MORFEO software packages, i.e. the principles of the extended finite element method (eng. XFEM), were used to solve the problem of assessing the integrity of the rotary equipment of the hydroelectric shaft. As input data in application of XFEM method using aforementioned packages, experimental results obtained by using concept of elastic-plastic fracture mechanics i.e. application of the well-known Paris law with the aim of determining the fatigue crack growth rate are used. The data obtained by experimental tests, specifically the values of parameters C and m of the well-known Paris law, were the basis for numerical simulations of fatigue crack growth in the turbine shaft using the law of linear-elastic fracture mechanics. In addition, in this study, a stress analysis of the turbine shaft was performed, as well as a direct comparison of analytical and numerical results. The main goal of the entire study can be reduced to the explanation of the complex state and general behavior of the rotary equipment, i.e. the turbine shaft in the presence of cracks caused by fatigue load and in the presence of a stress concentrator. It can be pointed out that the main objective of this study is to determine the dependence of crack growth rate on crack size for a certain shaft geometry on the basis of which it is possible to estimate the integrity and life of the shaft, in addition to all known material properties. Indirectly, the developed and presented numerical models in this dissertation, as well as experimental procedures that have great applicability in integrity assessment of this type equipment,viii also provide scientific and engineering contributions of this study analysis, like determining integrity and remaining life of the equipment exposed to a fatigue load in the presence of a crack

Impact of the process of polymerization of polyol and toluen diisocyanate on the environoment

The aim of this study was to investigate the impact of the process of polymerization of polyiol and tolyendiisocyanate on the environoment. Toluene diisocyanates are important industryal intermediates used in conjunction with polyether and polyester polyols as coreactants polyurethane foams, paints, varnishes, elasomers and coatings. This presentation summarizes existing information on the release and behavior of the process of polymerization of polyol and toluen diisocyanate on the environment. A major reaction of TDI in the environoment is formation of solid inert polyureas from reaction with water. In use, TDI is reacted with polyols to form many different polyurethane products. Polyurethanes have been show to be stable in the environment and in disposal have no adverse impact on municipal waste handling processes, landfills or incineration.Physical chemistry 2006 : 8th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 26-29 September 200

Улога методологије архитектонског програмирања у процесу пројектовања морфологије простора: пример Трећег Београда

Предметна дисертација се гради на уверењу да је потреба за специфичним аналитичким истраживачким стратегијама и развојем методолошког оквира за њихову примену један од централних проблема у савременом делокругу архитектонског истраживања, едукације и праксе и у том смислу фокус усмерава ка откривању савремене природе методологије архитектонског програмирања, њеног развоја и корена. Повод и актуелност теме истраживања се тако огледа у неопходности редефинисања концептуалног и методолошког оквира програма у архитектонском дискурсу и пројектантском процесу у складу са актуелним пројектантским методама и школама мишљења. Како би се испитали сви изазови унутар пројектантске дисциплине, те осветлила процесна природа пројектовања, тематски оквир истраживања се усмерава ка парадигматској аргументацији методологије архитектонског програмирања и њеног положаја у савременом контексту истраживања и праксе кроз троструку истраживачку позицију – епистемологију, праксиологију и феноменологију пројектовања. Основни циљ истраживања је усмерен на развој научно заснованог приказа и критичке експликације о позицији и улози концептуалнометодолошког оквира програма у архитектонском дискурсу као аналитичког и вишекритеријумски усмереног апарата за систематизацију идеја, дефинисање пројектног проблема и евалуацију финалног пројектантског решења. Резултати истраживања укључују: (1) концепт – систематизовани преглед развоја теоријске мисли и практичне примене методологије програмирања и развоја дефиниције програма у архитектонском дискурсу уз хронолошки преглед библиографских извора и класификацију преседана према парадигмама, (2) контекст – систематизован преглед развоја и примене методологије програмирања у локалном контексту, и (3) курикулум – идентификацију програмских перспектива и модела и експликацију њихове улоге у оквиру савремених архитектонских истраживања, едукације и праксе. Кроз проучавање основних пројектантских метода и фокусно методологије архитектонског програмирања, дисертација је резултирала не само систематизованим прегледом података о анализи тематског оквира, већ и практичним сазнањима о релацијама између програмских перспектива и морфологије простора. Додатно, примена резултата истраживања успостављена је увођењем посредног предмета истраживања, просторног обухвата Трећег Београда.The dissertation is based on the belief that the need for specific analytical research strategies and the development of a methodological framework for their application are the central problems in the contemporary field of architectural research, education, and practice. In this sense, the focus is on discovering the contemporary nature of architectural programming methodology, its development, and its roots. The reason and topicality of the research are thus reflected in the need to redefine the conceptual and methodological framework of the program in architectural discourse and design process in accordance with new generations of design methods and schools of thought. In order to decode all challenges within the design discipline, and highlight the process-based nature of design, the thematic framework of research is directed towards paradigmatic argumentation of architectural programming methodology and its position in the contemporary context of research and practice through a triple research position – epistemology, praxiology and phenomenology of design. The primary goal of the research is aimed at developing a scientifically-based presentation and critical explanation of the position and role of the conceptual-methodological framework of the program in architectural discourse as an analytical and multicriteria-oriented apparatus for systematizing ideas, defining design problems, and evaluating final design solutions. The research results include three pillars: (1) concept – systematized review of the theoretical framework and practical application of architectural programming methodology, and program definition in architectural discourse with a chronological review of bibliographic sources and classification of precedents by paradigms, (2) context – systematic review of architectural programming methodology development and application in the local context, and (3) curriculum – identification of programming perspectives and models, and explication of their role within contemporary architectural research, education and practice. Through the study of fundamental design methods and methodology of architectural programming, the dissertation resulted not only in a systematized paradigmatic review, but also in practical knowledge of the relationship between programming perspectives and spatial morphology. In addition, the application of research results was established by the introduction of an indirect subject of research, the spatial framework of the Third Belgrade

Terapija endometritisa krmača intrauterinom instilacijom preparata na bazi zida kvasca

On the basis of our investigations it was possible to conclude that intrauterine treatment of sows with puerperal uterine infections with sterile YCW (Yeast Cell Wall) resulted in significant clinical improvement. The percent of recidivism was the lowest (10%) in groups of sows treated with 10 and 20 g of YCW. The degree of bacterial CFU (Colony Forming Units) reduction in samples of sows uterine flushings following instillation of YCW (5, 10 and 20 g) was wery high and ranged from 1361 to 1444 times, while in sows treated with Lotagen 2% solution (100 mL) this parametar was only 32. At the moment of weaning, piglets from sows treated with 10 and 20 g of YCW were heavier when compared to the control and Lotagen group and their DBWG (Daily Body Weight Gain) was higher when compared to the Lotagen and control group. Treatment of sows by IU instillation of YCW did not influence the number of piglets in the next breeding cycle.Na osnovu rezultata naših istraživanja bilo je moguće zaključiti da tretman krmača obolelih od puerperalnih infekcija materice, sterilnim preparatom dobijenim iz zida kvasca (YCW), ima za posledicu značajan klinički napredak. Procenat krmača sa recidivom je bio najniži (10%) u grupi tretiranoj sa 10 i 20g YCW. Stepen redukcije broja bakterijskih kolonija (CFU) u uzorcima dobijenih iz materice krmača posle tretmana YCW preparatom je bio veoma visok i kretao se u opsegu od 1361 do 1444 puta. Kod obolelih krmača, tretiranih rastvorom Lotagena (2%), vrednost ovog parametra je bila svega 32. U momentu zalučenja, prasad krmača tretiranih YCW preparatom u količini od 10 i 20 g bila su teža u poređenju sa prasadima krmača grupe tretirane Lotagenom i prasadima kontrolnih (neteretiranih) krmača. Osim toga i njihovi prosečni dnevni prirasti su bili veći. Tretman krmača intrauterinom instilacijom preparata na bazi YCW nije negativno uticao na broj prasadi u sledećem reproduktivnom ciklusu

Composite bosons in bilayer nu = 1 system: An application of the Murthy-Shankar formalism

We calculate the dispersion of the out-of-phase mode characteristic for the bilayer nu = 1 quantum Hall system applying the version of Chern-Simons theory of Murthy and Shankar that cures the unwanted bare electron mass dependence in the low-energy description of quantum Hall systems. The obtained value for the mode when d, distance between the layers, is zero is in a good agreement with the existing pseudospin picture of the system. For d nonzero but small we find that the mode is linearly dispersing and its velocity to a good approximation depends linearly on d. This is in agreement with the Hartree-Fock calculations of the pseudospin picture that predicts a linear dependance on d, and contrary to the naive Hartree predictions with dependence on the square-root of d. We set up a formalism that enables one to consider fluctuations around the found stationary point values. In addition we address the case of imbalanced layers in the Murthy-Shankar formalism.Comment: 10 pages, 1 figur