Laser shock peening of N-155 superalloy after longtime service

Uzorci superlegure željeza N-155 isječeni su iz lopatice turbine nakon dugotrajnog rada na povišenim temperaturama i tlakovima. Uzorci su izloženi impulsima lasera različitih parametara, promatrani skenirajućim elektronskim mikroskopom (SEM) i analizirani energodisperzivnom spektrometrijom (EDS). U ovisnosti o parametrima lasera, interakcija laserskog snopa i materijala je u nekim slučajevima promatrana kao mehanička, a u drugim kao termomehanička obrada. Mikrotvrdoće su mjerene po Vikersu. U ovom radu, analizirane su mikrostrukture nastale nakon različitih frekvencija impulsa i zatim uspoređene.Iron base superalloy N-155 samples have been cut from the turbine blade which had been exposed to elevated pressure and temperature during its long-time service. The samples have been irradiated with pulsed laser beam, observed with scanning electron microscopy (SEM) and analysed by energo-dispersive spectrometry (EDS). The range of implemented beam parameters for which two types of treatments – mechanical and thermo-mechanical – occurred, has been determined. Vickers micro hardness tests have shown the increase in micro hardness after laser treatment

Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop.

We now know RNA can survive the harsh environment of biofluids when encapsulated in vesicles or by associating with lipoproteins or RNA binding proteins. These extracellular RNA (exRNA) play a role in intercellular signaling, serve as biomarkers of disease, and form the basis of new strategies for disease treatment. The Extracellular RNA Communication Consortium (ERCC) hosted a two-day online workshop (April 19-20, 2021) on the unique challenges of exRNA data analysis. The goal was to foster an open dialog about best practices and discuss open problems in the field, focusing initially on small exRNA sequencing data. Video recordings of workshop presentations and discussions are available (https://exRNA.org/exRNAdata2021-videos/). There were three target audiences: experimentalists who generate exRNA sequencing data, computational and data scientists who work with those groups to analyze their data, and experimental and data scientists new to the field. Here we summarize issues explored during the workshop, including progress on an effort to develop an exRNA data analysis challenge to engage the community in solving some of these open problems

Open problems in extracellular RNA data analysis : insights from an ERCC online workshop

We now know RNA can survive the harsh environment of biofluids when encapsulated in vesicles or by associating with lipoproteins or RNA binding proteins. These extracellular RNA (exRNA) play a role in intercellular signaling, serve as biomarkers of disease, and form the basis of new strategies for disease treatment. The Extracellular RNA Communication Consortium (ERCC) hosted a two-day online workshop (April 19-20, 2021) on the unique challenges of exRNA data analysis. The goal was to foster an open dialog about best practices and discuss open problems in the field, focusing initially on small exRNA sequencing data. Video recordings of workshop presentations and discussions are available (https://exRNA.org/exRNAdata2021-video). There were three target audiences: experimentalists who generate exRNA sequencing data, computational and data scientists who work with those groups to analyze their data, and experimental and data scientists new to the field. Here we summarize issues explored during the workshop, including progress on an effort to develop an exRNA data analysis challenge to engage the community in solving some of these open problems