Pisanje prikaza bolesnika na engleskom jeziku

A well-written case report is a clear, concise and informative paper, aimed at professionals from different fields of medicine, with the clear purpose to explain what lesson is to be learnt from the experience. The aim of this paper is to suggest useful guidelines for writing a good case report. It briefly reflects different 'moves' in this piece of academic writing, thus outlining the required form, as well as the four principles of good writing: clarity, honesty, reality and relevance.Dobro napisan prikaz bolesnika je jasan, koncizan i informativan rad namenjen stručnjacima iz različitih oblasti medicine s jasnim ciljem da objasni šta treba naučiti na osnovu datog iskustva. Cilj ovog rada je da prikaže korisne smernice za pisanje dobrog prikaza bolesnika. U radu je dat kratak osvrt na različite 'korake' U vezi s formom ove vrste akademskog pisanja. Rad takođe opisuje četiri principa dobrog pisanja, a to su: jasnoća, istinitost, realnost i relevantnost

Speleological objects of Sokobanja as potential Palaeolithic sites

This monograph connects to the research results Petar Milojević presented in his graduation paper titled “The Survey of potential Paleolithic sites in the region of the Sokobanja basin and closer vicinity” the research for which was conducted within the project “Research of the transition from the middle to the upper Paleolithic in eastern Serbia” conducted by the Faculty of Philosophy from Belgrade in cooperation with the University of Arizona from Tucson (USA), under the auspices of Dušan Mihailović and Steven Kuhn. The research was conducted based on data collected by a team of three authors during only two research campaign each of which lasted two weeks conducted during 2012 and 2013. Such a speed of work would not have been possible without the generous assistance of the population from the Sokobanja basin, who have shown great interest for our research at every site we have visited in their area. They have not just pointed their fingers at topographic maps we carried with us or just pointed in the direction we should go; they assisted us as guides often neglecting their personal affairs. Thus they have spared us from wandering around during the localization of speleological objects, which were quite often covered by vegetation and difficult to notice even from close distance. They have also spared us the risk of getting lost and walking in circles in landscapes such as are the numerous sinkholes on Mount Devica. We owe special thanks to: Saša Stevanović, who guided us to most of the caves; Igor Lazić, Aca Marinković, Zoran Stojadinović, Stevan Bašić, Miodrag Milutinović, Dragi Stanojević, Dragan Milanović, Đorđe Jančić, Danijela Stanojević, Dejan Stanojević, Marijana Marinković, Jelena Milojević, Prilagija Milojević and Ana Dinić for their personal contribution to our research. Our gratitude also goes to the professors of the Faculty of Philosophy from Belgrade, Dušan Mihailović and Vesna Dimitrijević because without their expert support this research could not have been adequately conducted.in Serbian [https://rai.ai.ac.rs/handle/123456789/1149

Rana alergijska reakcija na metilprednizolon sa tolerancijom drugih kortikosteroida

Introduction. In spite of the wide usage of corticosteroids for the treatment of a plethora of diseases, sometimes they can induce immediate hypersensitivity reactions, which are however uncommon. Case Outline. We report a case of immediate allergic reaction induced by intravenous methylprednisolone given before operation for surgical repair of an arm contracture as a sequel of burns, which the child had tolerated a month before. Six weeks later the patient repeated the anaphylactic reaction during skin testing to methylprednisolone. In addition, basophile activation test with methylprednisolone (BAT) was positive. Conclusion. This case report describes a patient who experienced intraoperative anaphylaxis and anaphylactic reaction induced by skin testing. This is the first report on induction of both anaphylactic reactions by methylprednisolone in the same child. Clinical findings, positive BAT and positive skin tests with methylprednisolone imply that the child developed type-I hypersensitivity. The lack of cross-reactivity with other corticosteroids emphasizes that the reactions were caused by the steroid molecule.Uvod. Uprkos širokoj primeni kortikosteroida u lečenju od različitih bolesti, oni ponekad mogu izazvati ranu alergijsku reakciju. Prikaz bolesnika. Kod dvanaestogodišnjeg dečaka došlo je do rane alergijske reakcije izazvane intravenskom primenom metilprednizolona neposredno pre hirurške intervencije, tačnije, korekcije kontrakture šake koja se javila kao komplikacija opekotine. Mesec dana pre pojave alergijske reakcije dete je primalo metilprednizolon i dobro ga podnosilo. Šest nedelja posle operacije ponovo se javila anafilaktička reakcija tokom kožnog testiranja metilprednizolonom. Primenjen je i test aktivacije bazofila (BAT) ovim lekom, čiji je nalaz bio pozitivan. Zaključak. Ovo je prvi prikaz dve vrste anafilaktičke reakcije izazvane metilprednizolonom kod iste osobe. Klinička slika, pozitivni nalaz BAT i pozitivne kožne probe na metilprednizolon pokazuju da se kod deteta razvio prvi tip hipersenzitivne reakcije. Nedostatak unakrsne reaktivnosti s ostalim kortikosteroidima ukazuje na to da je alergijska reakcija izazvana steroidnim molekulom

Myocarditis exacerbation in a child undergoing inguinal hernioplasty after viral infection

Introduction Immunosuppressive effects of general anesthesia and surgery could have unexpected consequences in a child with recent infection. The incidence of myocarditis in childhood is unknown. Case outline During general anesthesia for inguinal hernia repair, a seven-year-old boy suddenly developed heart failure. Clinical presentation included hypotension, pulmonary edema, drop in hemoglobin oxygen saturation, ST segment elevation and premature ventricular contractions. Homodynamic stability and adequate oxygenation were achieved with dopamine and furosemide. Preoperative history, physical examination and complete blood count were unremarkable. Moderate cardiomegaly and pulmonary edema were present on chest radiography. Diminished left ventricular contractility found on echocardiography increased troponin I and CK-MB levels suggested myocardial injury. Increased C-reactive protein with lymphocytosis suggested inflammation as its cause. Parents failed to report rubella 10 days before the operation. A clinical diagnosis of myocarditis as a complication of rubella was based on increased titer of IgM to rubella. With intravenous immunoglobulin, corticosteroids and symptomatic treatment for heart failure, his condition improved and ejection fraction reached 68 % one month after operation. Conclusion In future, we need protocols with instructions for pediatric patients undergoing elective surgery and anesthesia after viral infections

Anaesthesia in children with inherited neuromuscular diseases

Children with inherited neuromuscular diseases often require anaesthesia for diagnostic or therapy procedures. These patients have an increased risk of perioperative complications due to the nature of the disease and medications administered during anaesthesia. Many anaesthetics and muscle relaxants can aggravate the underlying disease and trigger life-threatening reactions (cardiorespiratory complications, malignant hyperthermia). Besides, the neuromuscular disorders are associated with atypical and undesirable responses to drugs used during anaesthesia and the perioperative period. The paper presents pathophysiological basis of inherited/genetic neuromuscular diseases and specific anaesthesiological problems. The recommendations are suggested with the aim to make the perioperative course in children optimally safe

Anaesthesia in children with inherited neuromuscular diseases

Children with inherited neuromuscular diseases often require anaesthesia for diagnostic or therapy procedures. These patients have an increased risk of perioperative complications due to the nature of the disease and medications administered during anaesthesia. Many anaesthetics and muscle relaxants can aggravate the underlying disease and trigger life-threatening reactions (cardiorespiratory complications, malignant hyperthermia). Besides, the neuromuscular disorders are associated with atypical and undesirable responses to drugs used during anaesthesia and the perioperative period. The paper presents pathophysiological basis of inherited/genetic neuromuscular diseases and specific anaesthesiological problems. The recommendations are suggested with the aim to make the perioperative course in children optimally safe

Preventive effect of ursodeoxycholic acid on parenteral nutrition-associated liver disease in infants

Introduction. Parenteral nutrition-associated cholestasis is well recognized phenomenon in the term and preterm infant receiving long-term parenteral nutrition. Objectives. The aim of this study was to evaluate the effect of ursodeoxycholic acid (UDCA) use on cholestasis in newborns on prolonged TPN. Methods. A total of 56 infants were enrolled in this retrospective study: control group consisted of lower (1500 g) birth weight infants (n=30), as well as the group of pediatric (n=11) and surgical patients (n=15) treated with UDCA. Blood chemistries were obtained two times weekly. Results. All of 56 newborns developed cholestasis but duration of parenteral nutrition (PN) before onset of cholestasis was significantly longer in UDCA treated patients. Average duration of PN before the onset of cholestasis in control group of patients was 25 days in distinction from treated pediatric and surgical patients (39 and 34 days, respectively). The peak serum conjugated bilirubin (CB), AST, ALT and alkaline phosphatase (AP) levels were significantly lower in the treated groups. There was no significant difference among treated pediatric and surgical patients and between lower and higher birth weight infants considering the CB, ALT, AST and AP peak. Duration of cholestasis was significantly decreased in all treated groups. There was a significant difference in time needed to achieve complete enteral intake between pediatric and surgical patient group. Conclusion. Cholestasis developed significantly later in treated groups than in the controls. UDCA appears to be very successful in reducing the symptoms of cholestasis. The difference in efficacy of UDCA treatment between lower and higher birth weight infants could not be proven