Description and pilot evaluation of the Metabolic Irregularities Narrowing down Device software: a case analysis of physician programming

Background: There is a gap between the abilities and the everyday applications of Computerized Decision Support Systems (CDSSs). This gap is further exacerbated by the different ‘worlds’ between the software designers and the clinician end-users. Software programmers often lack clinical experience whereas practicing physicians lack skills in design and engineering. Objective: Our primary objective was to evaluate the performance of Metabolic Irregularities Narrowing down Device (MIND) intelligent medical calculator and differential diagnosis software through end-user surveys and discuss the roles of CDSS in the inpatient setting. Setting: A tertiary care, teaching community hospital. Study participants: Thirty-one responders answered the survey. Responders consisted of medical students, 24%; attending physicians, 16%, and residents, 60%. Results: About 62.5% of the responders reported that MIND has the ability to potentially improve the quality of care, 20.8% were sure that MIND improves the quality of care, and only 4.2% of the responders felt that it does not improve the quality of care. Ninety-six percent of the responders felt that MIND definitely serves or has the potential to serve as a useful tool for medical students, and only 4% of the responders felt otherwise. Thirty-five percent of the responders rated the differential diagnosis list as excellent, 56% as good, 4% as fair, and 4% as poor. Discussion: MIND is a suggesting, interpreting, alerting, and diagnosing CDSS with good performance and end-user satisfaction. In the era of the electronic medical record, the ongoing development of efficient CDSS platforms should be carefully considered by practicing physicians and institutions

Remediation of arsenic contaminated water by a novel carboxymethyl cellulose bentonite adsorbent

Suitability of bentonite clay modified with sodium carboxymethyl cellulose (Na-CMC) for the removal of arsenic(III) ions from aqueous solution was tested in batch adsorption studies and complemented by theoretical modeling with Langmuir, Freundlich and Temkin isotherm models. The effects of various factors, such as the initial adsorbate concentrations, pH, and temperature of the solutions were investigated in series of experiments. FTIR analysis was used to detect functional groups typical for cellulose and bentonite. Scanning electron microscope was used to analyze the surface morphology of the composites. It was established that the removal process was fast in the beginning and adsorption equilibrium was attained in around 20 minutes with good fittings to both Langmuir and Freundlich model. Maximum adsorption capacity (Q max ) obtained from experiments was 9.4 mg/g. No influence of solution pH and temperature on the sorption was noticed. The series of conducted experiments showed that synthesized composites are suitable for the removal of arsenic from wastewaters by adsorption as efficient and low-cost technique. © 2019, ALÖKI Kft., Budapest, Hungary

Supplementary material for the article: Wedmann, R.; Onderka, C.; Wei, S.; Szijártó, I. A.; Miljkovic, J. L.; Mitrovic, A.; Lange, M.; Savitsky, S.; Yadav, P. K.; Torregrossa, R.; et al. Improved Tag-Switch Method Reveals That Thioredoxin Acts as Depersulfidase and Controls the Intracellular Levels of Protein Persulfidation. Chemical Science 2016, 7 (5), 3414–3426. https://doi.org/10.1039/c5sc04818d

Supplementary material for: [https://doi.org/10.1039/c5sc04818d]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1925

Supplementary data for article: Snijder, P. M.; Baratashvili, M.; Grzeschik, N. A.; Leuvenink, H. G. D.; Kuijpers, L.; Huitema, S.; Schaap, O.; Giepmans, B. N. G.; Kuipers, J.; Miljkovic, J. L.; et al. Overexpression of Cystathionine γ-Lyase Suppresses Detrimental Effects of Spinocerebellar Ataxia Type 3. Molecular Medicine 2015, 21, 758–768. https://doi.org/10.2119/molmed.2015.00221

Supplementary material for: [https://doi.org/10.2119/molmed.2015.00221]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2255

Supplementary data for article: Snijder, P. M.; Baratashvili, M.; Grzeschik, N. A.; Leuvenink, H. G. D.; Kuijpers, L.; Huitema, S.; Schaap, O.; Giepmans, B. N. G.; Kuipers, J.; Miljkovic, J. L.; et al. Overexpression of Cystathionine γ-Lyase Suppresses Detrimental Effects of Spinocerebellar Ataxia Type 3. Molecular Medicine 2015, 21, 758–768. https://doi.org/10.2119/molmed.2015.00221

Supplementary material for: [https://doi.org/10.2119/molmed.2015.00221]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2255

Organically vs. Conventionally Grown Vegetables: Multi-elemental Analysis and Nutritional Evaluation

Vegetables are important contributors to a healthy diet, and their adequate daily intake can help prevent some of the major illnesses. The aimof the study was to examine the content of the major and trace elements in selected organically grown (OG) and conventionally grown (CG) vegetables (cabbage, kohlrabi, Brussels sprout, beetroot, carrot, potato, and onion), taken from city green markets. Multi-elemental analysis was carried out by inductively coupled plasma method with optical emission spectrometry (ICP-OES). Nutritional quality evaluation in comparison to nutritional reference values was done. In studied vegetables, Al, Ca, K, Fe (with the exception of organic kohlrabi), Mg, Na, P, S, and Zn were quantified in all samples, whereas As, Cd, Co, Hg, Se, and V were below the limit of detection for these elements. Macroelements and trace elements were found at higher concentrations in OG and CG vegetables, respectively. Differences in concentrations of studied elements between the same vegetable species produced in two agricultural systems were significant, except for beetroot (p ≤ 0.05). Principal component analysis and hierarchical cluster analysis results showed that the botanical origin had higher influence on sample differentiation than the agronomic practice, which was in accordance with the results obtained by Mann-Whitney U test. Good quality of both OG and CG vegetables in respect of nutritionally beneficial elements was observed

Analysis of the state of vegetation in the municipality of Jagodina (Serbia) through remote sensing and suggestions for protection

Both environmental control and appropriate measurement results present basis for the quality protection of geospatial elements. Providing environmental monitoring activities and creating control network is the obligation of each state, whereas local communities provide observation and control of air quality, water quality, waste quality, soil quality, vegetation and land cover control, etc. This has been the reason for the analysis of vegetation of the municipality of Jagodina in Serbia. By processing satellite images, data on the sources of pollution and polluting materials of the vegetation have been discovered. These include spot (stationary), linear (mobile and stationary) and surface (stationary and mobile) sources. While processing satellite images by the Idrisi software, we have acquired results that indicate certain vegetation modifications (images obtained through infrared spectral imaging). Results obtained through remote sensing indicate the necessity to define adequate vegetation monitoring, to complete a register of pollutants, to set up information system and define ways of data presentation in order to manage a single, complete register of environmental pollutants in the municipality of Jagodina