5,029 research outputs found
Structure of bottle-brush brushes under good solvent conditions. A molecular dynamics study
We report a simulation study for bottle-brush polymers grafted on a rigid
backbone. Using a standard coarse-grained bead-spring model extensive molecular
dynamics simulations for such macromolecules under good solvent conditions are
performed. We consider a broad range of parameters and present numerical
results for the monomer density profile, density of the untethered ends of the
grafted flexible backbones and the correlation function describing the range
that neighboring grafted bottle-brushes are affected by the presence of the
others due to the excluded volume interactions. The end beads of the flexible
backbones of the grafted bottle-brushes do not access the region close to the
rigid backbone due to the presence of the side chains of the grafted
bottle-brush polymers, which stretch further the chains in the radial
directions. Although a number of different correlation lengths exist as a
result of the complex structure of these macromolecules, their properties can
be tuned with high accuracy in good solvents. Moreover, qualitative differences
with "typical" bottle-brushes are discussed. Our results provide a first
approach to characterizing such complex macromolecules with a standard bead
spring model.Comment: To appear in Journal of Physics Condensed Matter (2011
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Using local ecological knowledge to assess the status of the Critically Endangered Chinese giant salamander Andrias davidianus in Guizhou Province, China
The Critically Endangered Chinese giant salamander Andrias davidianus, the world's largest amphibian, is severely threatened by unsustainable exploitation of wild individuals. However, field data with which to assess the salamander's status, population trends, or exploitation across its geographical range are limited, and recent field surveys using standard ecological field techniques have typically failed to detect wild individuals. We conducted community-based fieldwork in three national nature reserves (Fanjingshan, Leigongshan and Mayanghe) in Guizhou Province, China, to assess whether local ecological knowledge constitutes a useful tool for salamander conservation. We collected a sample of dated salamander sighting records and associated data from these reserves for comparative assessment of the relative status of salamander populations across the region. Although Fanjingshan and Leigongshan are still priority sites for salamander conservation, few recent sightings were recorded in either reserve, and respondents considered that salamanders had declined locally at both reserves. The species may already be functionally extinct at Mayanghe. Although respondent data on threats to salamanders in Guizhou are more difficult to interpret, overharvesting was the most commonly suggested explanation for salamander declines, and it is likely that the growing salamander farming industry is the primary driver of salamander extraction from Guizhou's reserves. Questionnaire-based surveys can collect novel quantitative data that provide unique insights into the local status of salamander populations, and we advocate wide-scale incorporation of this research approach into future salamander field programmes
Soleus stretch reflex during cycling
The modulation and strength of the human soleus short latency stretch reflex was investigated by mechanically perturbing the ankle during an unconstrained pedaling task. Eight subjects pedaled at 60 rpm against a preload of 10 Nm. A torque pulse was applied to the crank at various positions during the crank cycle, producing ankle dorsiflexion perturbations of similar trajectory. The stretch reflex was greatest during the power phase of the crank cycle and was decreased to the level of background EMG during recovery. Matched perturbations were induced under static conditions at the same crank angle and background soleus EMG as recorded during the power phase of active pedaling. The magnitude of the stretch reflex was not statistically different from that during the static condition throughout the power phase of the movement. The results of this study indicate that the stretch reflex is not depressed during active cycling as has been shown with the H-reflex. This lack of depression may reflect a decreased susceptibility of the stretch reflex to inhibition, possibly originating from presynaptic mechanisms
One- and two-particle microrheology
We study the dynamics of rigid spheres embedded in viscoelastic media and
address two questions of importance to microrheology. First we calculate the
complete response to an external force of a single bead in a homogeneous
elastic network viscously coupled to an incompressible fluid. From this
response function we find the frequency range where the standard assumptions of
microrheology are valid. Second we study fluctuations when embedded spheres
perturb the media around them and show that mutual fluctuations of two
separated spheres provide a more accurate determination of the complex shear
modulus than do the fluctuations of a single sphere.Comment: 4 pages, 1 figur
Competing Harvesting Strategies In A Simulated Population Under Uncertainty
We present a case study of the use of simulation modelling to develop and test strategies for managing populations under uncertainty. Strategies that meet a stock conservation criterion under a base case scenario are subjected to a set of robustness trials, including biased and highly variable abundance estimates and poaching. Strategy performance is assessed with respect to a conservation criterion, the revenues achieved and their variability. Strategies that harvest heavily, even when the population is apparently very large, perform badly in the robustness trials. Setting a threshold below which harvesting does not take place, and above which all individuals are harvested, does not provide effective protection against over-harvesting. Strategies that rely on population growth rates rather than estimates of population size are more robust to biased estimates. The strategies that are most robust to uncertainty are simple, involving harvesting a relatively small proportion of the population each year. The simulation modelling approach to exploring harvesting strategies is suggested as a useful tool for the assessment of the performance of competing strategies under uncertainty
Fluctuations of a driven membrane in an electrolyte
We develop a model for a driven cell- or artificial membrane in an
electrolyte. The system is kept far from equilibrium by the application of a DC
electric field or by concentration gradients, which causes ions to flow through
specific ion-conducting units (representing pumps, channels or natural pores).
We consider the case of planar geometry and Debye-H\"{u}ckel regime, and obtain
the membrane equation of motion within Stokes hydrodynamics. At steady state,
the applied field causes an accumulation of charges close to the membrane,
which, similarly to the equilibrium case, can be described with renormalized
membrane tension and bending modulus. However, as opposed to the equilibrium
situation, we find new terms in the membrane equation of motion, which arise
specifically in the out-of-equilibrium case. We show that these terms lead in
certain conditions to instabilities.Comment: 7 pages, 2 figures. submitted to Europhys. Let
Guiding principles for evaluating the impacts of conservation interventions on human well-being
Measures of socio-economic impacts of conservation interventions have largely been restricted to externally defined indicators focused on income, which do not reflect people's priorities. Using a holistic, locally grounded conceptualization of human well-being instead provides a way to understand the multi-faceted impacts of conservation on aspects of people's lives that they value. Conservationists are engaging with well-being for both pragmatic and ethical reasons, yet current guidance on how to operationalize the concept is limited. We present nine guiding principles based around a well-being framework incorporating material, relational and subjective components, and focused on gaining knowledge needed for decision-making. The principles relate to four key components of an impact evaluation: (i) defining well-being indicators, giving primacy to the perceptions of those most impacted by interventions through qualitative research, and considering subjective well-being, which can affect engagement with conservation; (ii) attributing impacts to interventions through quasi-experimental designs, or alternative methods such as theory-based, case study and participatory approaches, depending on the setting and evidence required; (iii) understanding the processes of change including evidence of causal linkages, and consideration of trajectories of change and institutional processes; and (iv) data collection with methods selected and applied with sensitivity to research context, consideration of heterogeneity of impacts along relevant societal divisions, and conducted by evaluators with local expertise and independence from the intervention
Strong-Segregation Theory of Bicontinuous Phases in Block Copolymers
We compute phase diagrams for starblock copolymers in the
strong-segregation regime as a function of volume fraction , including
bicontinuous phases related to minimal surfaces (G, D, and P surfaces) as
candidate structures. We present the details of a general method to compute
free energies in the strong segregation limit, and demonstrate that the gyroid
G phase is the most nearly stable among the bicontinuous phases considered. We
explore some effects of conformational asymmetry on the topology of the phase
diagram.Comment: 14 pages, latex, 21 figures, to appear in Macromolecule
The effects of climatic fluctuations and extreme events on running water ecosystems
Most research on the effects of environmental change in freshwaters has focused on incremental changes in average conditions, rather than fluctuations or extreme events such as heatwaves, cold snaps, droughts, floods or wildfires, which may have even more profound consequences. Such events are commonly predicted to increase in frequency, intensity and duration with global climate change, with many systems being exposed to conditions with no recent historical precedent. We propose a mechanistic framework for predicting potential impacts of environmental fluctuations on running water ecosystems by scaling up effects of fluctuations from individuals to entire ecosystems. This framework requires integration of four key components: effects of the environment on individual metabolism, metabolic and biomechanical constraints on fluctuating species interactions, assembly dynamics of local food webs and mapping the dynamics of the meta-community onto ecosystem function. We illustrate the framework by developing a mathematical model of environmental fluctuations on dynamically assembling food webs. We highlight (currently limited) empirical evidence for emerging insights and theoretical predictions. For example, widely supported predictions about the effects of environmental fluctuations are: high vulnerability of species with high per capita metabolic demands such as large-bodied ones at the top of food webs; simplification of food web network structure and impaired energetic transfer efficiency; reduced resilience and top-down relative to bottom-up regulation of food web and ecosystem processes. We conclude by identifying key questions and challenges that need to be addressed to develop more accurate and predictive bio-assessments of the effects of fluctuations, and implications of fluctuations for management practices in an increasingly uncertain world
Interfaces in Diblocks: A Study of Miktoarm Star Copolymers
We study AB miktoarm star block copolymers in the strong segregation
limit, focussing on the role that the AB interface plays in determining the
phase behavior. We develop an extension of the kinked-path approach which
allows us to explore the energetic dependence on interfacial shape. We consider
a one-parameter family of interfaces to study the columnar to lamellar
transition in asymmetric stars. We compare with recent experimental results. We
discuss the stability of the A15 lattice of sphere-like micelles in the context
of interfacial energy minimization. We corroborate our theory by implementing a
numerically exact self-consistent field theory to probe the phase diagram and
the shape of the AB interface.Comment: 12 pages, 11 included figure
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