Research requirements to reduce maintenance costs of civil helicopters

The maintenance problems faced by the operators of civil helicopters that result in high costs are documented. Existing technology that can be applied to reduce maintenance costs and research that should be carried out were identified. Good design practice and application of existing technology were described as having a significant impact on reducing maintenance costs immediately. The research and development that have potential for long range reduction of maintenance costs are presented

Investigation of phase-separated electronic states in 1.5µm GaInNAs/GaAs heterostructures by optical spectroscopy

We report on the comparative electronic state characteristics of particular GaInNAs/GaAs quantum well structures that emit near 1.3 and 1.5 µm wavelength at room temperature. While the electronic structure of the 1.3 µm sample is consistent with a standard quantum well, the 1.5 µm sample demonstrate quite different characteristics. By using photoluminescence sPLd excitation spectroscopy at various detection wavelengths, we demonstrate that the macroscopic electronic states in the 1.5 µm structures originate from phase-separated quantum dots instead of quantum wells. PL measurements with spectrally selective excitation provide further evidence for the existence of composition-separated phases. The evidence is consistent with phase segregation during the growth leading to two phases, one with high In and N content which accounts for the efficient low energy 1.5 µm emission, and the other one having lower In and N content which contributes metastable states and only emits under excitation in a particular wavelength range

The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats.

Corticotropin releasing factor receptor 1 (CRF1) is the key receptor that mediates stress-related body responses. However to date there are no CRF1 antagonists that have shown clinical efficacy in stress-related diseases. We investigated the inhibitory effects of a new generation, topology 2 selective CRF1 antagonists, NGD 98-2 and NGD 9002 on exogenous and endogenous CRF-induced stimulation of colonic function and visceral hypersensitivity to colorectal distension (CRD) in conscious rats. CRF1 antagonists or vehicle were administered orogastrically (og) or subcutaneously (sc) before either intracerebroventricular (icv) or intraperitoneal (ip) injection of CRF (10 µg/kg), exposure to water avoidance stress (WAS, 60 min) or repeated CRD (60 mmHg twice, 10 min on/off at a 30 min interval). Fecal pellet output (FPO), diarrhea and visceromotor responses were monitored. In vehicle (og)-pretreated rats, icv CRF stimulated FPO and induced diarrhea in >50% of rats. NGD 98-2 or NGD 9002 (3, 10 and 30 mg/kg, og) reduced the CRF-induced FPO response with an inhibitory IC50 of 15.7 and 4.3 mg/kg respectively. At the highest dose, og NGD 98-2 or NGD 9002 blocked icv CRF-induced FPO by 67-87% and decreased WAS-induced-FPO by 23-53%. When administered sc, NGD 98-2 or NGD 9002 (30 mg/kg) inhibited icv and ip CRF-induced-FPO. The antagonists also prevented the development of nociceptive hyper-responsivity to repeated CRD. These data demonstrate that topology 2 CRF1 antagonists, NGD 98-2 and NGD 9002, administered orally, prevented icv CRF-induced colonic secretomotor stimulation, reduced acute WAS-induced defecation and blocked the induction of visceral sensitization to repeated CRD

Concert recording 2017-04-14

[Track 1]. Wine and roses / Johnny Mercer arranged by Joe Pass -- [Track 2]. Confirmation / Charlie Parker -- [Track 3]. Exhausted / Malachi Million -- [Track 4]. Inner urge / Joe Henderson -- [Track 5]. Body and soul / Heyman, Sour, Eyton, Green -- [Track 6]. Unseemly / Malachi Million -- [Track 7]. Moment\u27s notice / John Coltrane -- [Track 8]. Inadequate / Malachi Million -- [Track 9]. Always and forever / Pat Metheny arranged by Malachi Million

Concert recording 2017-04-11c

[Track 1]. Misty / Erroll Garner -- [Track 2]. All the things you are / Jerome Kern -- [Track 3]. Giant steps / John Coltrane -- [Track 4]. Big sky [Track 5]. What lies ahead [Track 6]. Only this once [Track 7]. Think kindly of me / Drew Rogers

Exploring User Interface Improvements for Software Developers who are Blind

Software developers who are blind and interact with the computer non-visually face unique challenges with information retrieval. We explore the use of speech and Braille combined with software to provide an improved interface to aid with challenges associated with information retrieval. We motivate our design on common tasks performed by students in a software development course using a Microprocessor without Interlocked Pipeline Stages (MIPS) architecture simulation tool. We test our interface via a single-subject longitudinal study, and we measure and show improvement in both the user’s performance and the user experience

Concert recording 2016-04-19

[Track 01]. When sunny gets blue / Fischer ; arranged by Rogers -- [Track 02]. Alone together / Schwartz -- [Track 03]. Jitterbug Waltz / Waller -- [Track 04]. Moose the mooch / Parker -- [Track 05]. El Nino / Erquiaga -- [Track 06]. Wave / Jobim -- [Track 07]. Unit 7 / Jones

Energy from Agriculture

During the past few years, the demand for energy and petrochemicals has grown at a pace so rapid that our reserves of fossil fuels, once considered inexhaustible, are now being quickly depleted. To help lessen this impending problem, alternative sources of energy must be rapidly developed. Of the many new sources of energy being studied, solar energy, undisputedly, is the most inexhaustible. Energy from the sun, incident upon the earth\u27s surface, exceeds by nearly three orders of magnitude the total energy consumption today. Furthermore, it is not subject to nationalistic boundaries and its use would be compatible with our environmental goals. Several methods of using solar energy are under investigation

Energy From Biochemical Sources

As available energy reserves decline, renewable sources must be utilized. Organic matter, grown agriculturally, represents a renewable energy source, which is readily available. This paper reviews the methods by which organic matter can be converted to energy sources by biochemical processes. The economics of conversion of agricultural crops and byproducts to alcohols by fermentation and conversion of these agricultural materials to methane by anaerobic digestion are examined. Projections of the potential of this energy source are quite promising