244 research outputs found
Simplified direct water footprint model to support urban water management
Water resources conservation corresponding to urban growth is an increasing challenge for European policy makers. Water footprint (WF) is one of the methods to address this challenge. The objective of this study was to develop a simplified model to assess the WF of direct domestic and non-domestic water use within an urban area and to demonstrate its effectiveness in supporting new urban water management strategies and solutions. The new model was tested on three Central European urban areas with different characteristics i.e., Wroclaw (Poland), Innsbruck (Austria), and Vicenza (Italy). Obtained WFs varied from 291 dm3/(day∙capita) in Wroclaw, 551 dm3/(day∙capita) in Vicezna to 714 dm3/(day∙capita) in Innsbruck. In addition, WF obtained with the proposed model for the city of Vicenza was compared with a more complex approach. The results proved the model to be robust in providing reasonable results using a small amount of data
A gender-informed approach to nursing research
This session aims to provide nurse researchers with foundational knowledge to take a gender-informed approach to nursing research by being inclusive of all gender identities, from research proposal and demographics questionnaires, to the purpose of the research and dissemination of the results. Inclusivity of all genders can advance nursing research, education, and practice by guiding the development of knowledge and interventions to reduce disparities among all gender identities
Minimum Data Requirements For Integrating Urban Development And Urban Water Infrastructure Models
Data quality and availability is a common problem in many modelling studies dealing with regional, spatially distributed case studies. This is true for both, urban development models and urban water management models. As current research in urban water management more and more tries to benefit from an integrated view of the performance of water networks in the context of dynamically growing and shrinking cities, this problem of data scarcity increases. Having different applications with different levels of details available, the question arises which data (and which temporal and spatial resolution) is really necessary to be collected in a modeling study with a certain modeling aim. This work tackles this question by running an integrated urban development and urban water model with different detail levels of input data. The approach uses variations in quality (temporal and spatial) of input data for simulating urban development (population data & projections) and given data on existing city structures (e.g. buildings, road network). Permutations of the given information propagated through the urban development model represent several scenarios to calculate parameters for the urban water models (effective impervious area (EIA), dry weather flow (DWF) and water supply demand (WSD)) As urban water models in this study SWMM (storm water management model) for drainage systems and EPAnet for water supply systems is used. Consequently the impact of the input data variation on the results of the hydraulic and hydrodynamic simulations is statistically analyzed using different performance indicators: EIA in relation to ponded volume, DWF to flow velocities and WSD to system pressure clustered by input data. For comparison reasons simulation runs with a well-established urban development model are conducted
Negative regulation of human immune deficiency virus replication in monocytes. Distinctions between restricted and latent expression in THP- 1 cells
Childbirth and consequent atopic disease: emerging evidence on epigenetic effects based on the hygiene and EPIIC hypotheses
Background: In most high and middle income countries across the world, at least 1:4 women give birth by cesarean
section. Rates of labour induction and augmentation are rising steeply; and in some countries up to 50 % of laboring
women and newborns are given antibiotics. Governments and international agencies are increasingly concerned about
the clinical, economic and psychosocial effects of these interventions.
Discussion: There is emerging evidence that certain intrapartum and early neonatal interventions might affect the
neonatal immune response in the longer term, and perhaps trans-generationally. Two theories lead the debate in this
area. Those aligned with the hygiene (or ‘Old Friends’) hypothesis have examined the effect of gut microbiome colonization
secondary to mode of birth and intrapartum/neonatal pharmacological interventions on immune response and epigenetic
phenomena. Those working with the EPIIC (Epigenetic Impact of Childbirth) hypothesis are concerned with the effects of
eustress and dys-stress on the epigenome, secondary to mode of birth and labour interventions.
Summary: This paper examines the current and emerging findings relating to childbirth and atopic/autoimmune
disease from the perspective of both theories, and proposes an alliance of research effort. This is likely to accelerate
the discovery of important findings arising from both approaches, and to maximize the timely understanding of the
longer-term consequences of childbirth practices
Development of XMRV producing B Cell lines from lymphomas from patients with Chronic Fatigue Syndrome
Stronger together: Multi-annual variability of hydrogen production supported by wind power in Sweden
Hydrogen produced from renewable electricity will play an important role in deep decarbonisation of industry. However, adding large electrolyser capacities to a low-carbon electricity system also increases the need for additional electricity generation from variable renewable energies. This will require hydrogen production to be variable unless other sources provide sufficient flexibility. Existing sources of flexibility in hydro-thermal systems are hydropower and thermal generation, which are both associated with sustainability concerns. In this work, we use a dispatch model for the case of Sweden to assess the power system operation with large-scale electrolysers, assuming that additional wind power generation matches the electricity demand of hydrogen production on average. We evaluate different scenarios for restricting the flexibility of hydropower and thermal generation and include 29 different weather years to test the impact of variable weather regimes. We show that (a) in all scenarios electrolyser utilisation is above 60% on average, (b) the inter-annual variability of hydrogen production is substantial if thermal power is not dispatched for electrolysis, and (c) this problem is aggravated if hydropower flexibility is also restricted. Therefore, either long-term storage of hydrogen or backup hydrogen sources may be necessary to guarantee continuous hydrogen flows. Large-scale dispatch of electrolysis capacity supported by wind power makes the system more stable, if electrolysers ramp down in rare hours of extreme events with low renewable generation. The need for additional backup capacities in a fully renewable electricity system will thus be reduced if wind power and electrolyser operation are combined in the system
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