Eosinophil Cationic Protein Shows Survival Effect on H9c2 Cardiac Myoblast Cells with Enhanced Phosphorylation of ERK and Akt/GSK-3β under Oxidative Stress

To assess the knowledge and attitudes of pregnant Japanese women regarding non-invasive prenatal testing (NIPT). Between March and June 2013, 557 pregnant women in the Hyogo and Hiroshima Prefectures were surveyed using an anonymous, self-completed questionnaire. A total of 91.9ｵ respondents (512/557) stated that they “agree” or “conditionally agree” with NIPT implementation in Japan. Approximately 28.5ｵ of respondents stated that they knew that the accuracy of a positive NIPT result can be affected by motherʼs age and background, while 34.5ｵ of respondents stated that it was necessary for pregnant women with a positive result to undergo fetal chromosome diagnosis using amniocentesis;both percentages were low. Additionally, 92.3ｵ of respondents would “like a detailed explanation of the test,” 65.1ｵ of them would “like psychological support if the NIPT test results came back positive,” and 5.7ｵ would terminate the pregnancy if the NIPT test results came back positive without undergoing fetal chromosome diagnosis via amniocentesis. Although a high proportion of pregnant Japanese women agreed with the introduction of NIPT into Japanese obstetrical care, there was insufficient knowledge regarding the test. It is necessary for women undergoing NIPT to be provided sufficient information and psychological support

Fast Local Tone Mapping, Summed-Area Tables and Mesopic Vision Simulation

広島大学(Hiroshima University)博士(工学)Engineeringdoctora

Globalizing Regulation : The Issues of Governance and Politics

As economic, political and social activities are globalized, issues of global governance and the rule of law in international affairs are of acute concern. Global governance is a field of study that has complex and extensive sub-fields. The nature of international order, institutions and regimes are examined through analyses of the use of force and collective security,international trade and monetary relations,and international human rights.Not only the state but also non-state actors such as NGOs,businesses and international organizations are seen as important actors in global governance.This paper attempts to give an overview of the issues involved in global governance and politics.Article信州大学経済学論集 61: 91-100(2009)departmental bulletin pape

A Study on Displaying High Dynamic Range Images Considering Human Visual Perception

広島大学(Hiroshima University)博士(工学)Engineeringdoctora

Comparative Study of the Effectiveness of Oral Fluconazole and Intravaginal Clotrimazole in the Treatment of Vaginal Candidiasis

Objective: A study was carried out to compare 3 treatment regimens for vaginal candidiasis

Daptomycin approved in Japan for the treatment of methicillin-resistant Staphylococcus aureus

Daptomycin is a lipoglycopeptide antibacterial drug that is rapidly bactericidal for methicillin-resistant Staphylococcus aureus (MRSA) infection and has antibiotic activity against a wide range of Gram-positive organisms. It has been approved by the Ministry of Health, Labor and Welfare in Japan for the treatment for bacteremia, right-sided endocarditis, and skin and skin-structure infections, such as necrotizing fasciitis, due to MRSA on the basis of a Phase III trial conducted in Japan since July, 2011. In Japanese Phase I and III trials, daptomycin therapy given at 4 mg/kg and 6 mg/kg once per day was well tolerated and effective as standard therapy for the treatment of acute bacterial skin and skin-structure infections and bacteremia caused by MRSA, but side effects remain to be evaluated in large-scale trials