A novel CMB polarization likelihood package for large angular scales built from combined WMAP and Planck LFI legacy maps

We present a CMB large-scale polarization dataset obtained by combining WMAP Ka, Q and V with Planck 70 GHz maps. We employ the legacy frequency maps released by the WMAP and Planck collaborations and perform our own Galactic foreground mitigation technique, which relies on Planck 353 GHz for polarized dust and on Planck 30 GHz and WMAP K for polarized synchrotron. We derive a single, optimally-noise-weighted, low-residual-foreground map and the accompanying noise covariance matrix. These are shown, through $\chi^2$ analysis, to be robust over an ample collection of Galactic masks. We use this dataset, along with the Planck legacy Commander temperature solution, to build a pixel-based low-resolution CMB likelihood package, whose robustness we test extensively with the aid of simulations, finding excellent consistency. Using this likelihood package alone, we constrain the optical depth to reionazation $\tau=0.069^{+0.011}_{-0.012}$ at $68\%$ C.L., on 54\% of the sky. Adding the Planck high-$\ell$ temperature and polarization legacy likelihood, the Planck lensing likelihood and BAO observations we find $\tau=0.0714_{-0.0096}^{+0.0087}$ in a full $\Lambda$CDM exploration. The latter bounds are slightly less constraining than those obtained employing \Planck\ HFI CMB data for large angle polarization, that only include EE correlations. Our bounds are based on a largely independent dataset that does include also TE correlations. They are generally well compatible with Planck HFI preferring slightly higher values of $\tau$. We make the low-resolution Planck and WMAP joint dataset publicly available along with the accompanying likelihood code.Comment: The WMAP+LFI likelihood module is available on \http://www.fe.infn.it/u/pagano/low_ell_datasets/wmap_lfi_legacy

Cosmological constraints on the magnification bias on sub-millimetre galaxies after large-scale bias corrections

Context. The study of the magnification bias produced on high-redshift sub-millimetre galaxies by foreground galaxies through the analysis of the cross-correlation function was recently demonstrated as an interesting independent alternative to the weak-lensing shear as a cosmological probe. Aims. In the case of the proposed observable, most of the cosmological constraints mainly depend on the largest angular separation measurements. Therefore, we aim to study and correct the main large-scale biases that aect foreground and background galaxy samples to produce a robust estimation of the cross-correlation function. Then we analyse the corrected signal to derive updated cosmological constraints. Methods. We measured the large-scale, bias-corrected cross-correlation functions using a background sample of H-ATLAS galaxies with photometric redshifts >1.2 and two dierent foreground samples (GAMA galaxies with spectroscopic redshifts or SDSS galaxies with photometric ones, both in the range 0.2 < z < 0.8). These measurements are modelled using the traditional halo model description that depends on both halo occupation distribution and cosmological parameters. We then estimated these parameters by performing a Markov chain Monte Carlo under multiple scenarios to study the performance of this observable and how to improve its results. Results. After the large-scale bias corrections, we obtain only minor improvements with respect to the previous magnification bias results, mainly confirming their conclusions: a lower bound on m > 0:22 at 95% CL and an upper bound 8 < 0:97 at 95% CL (results from the zspec sample). Neither the much higher surface density of the foreground photometric sample nor the assumption of Gaussian priors for the remaining unconstrained parameters significantly improve the derived constraints. However, by combining both foreground samples into a simplified tomographic analysis, we were able to obtain interesting constraints on the m8 plane as follows: m = 0:50+0:14 0:20 and 8 = 0:75+0:07 0:10 at 68% C

Fetal-Perinatal Exposure to Bisphenol-A Affects Quality of Spermatozoa in Adulthood Mouse

Bisphenol-A (BPA) is considered an endocrine disruptor with estrogenic activity. It is described as an environment-polluting industrial chemical whose adverse effects on the male reproductive system depend on the period of exposure (i.e., fetal, prepubertal, or adult life). We exposed male mice to BPA during the fetal-perinatal period (from 10 days post coitum to 31 days post partum) and investigated the impact of this early-life exposure on gamete health in adulthood animals at 78 days of age. Both in control and BPA-exposed mice, viability and motility of spermatozoa, as well as sperm motility acquisition and chromatin condensation of spermatozoa, have been evaluated. Results reveal harmful effect of BPA on viability and motility of sperm cells as well as on chromatin condensation status during epididymal maturation of spermatozoa. In particular, BPA exposure interferes with biochemical mechanism useful to stabilize sperm chromatin condensation, as it interferes with oxidation of thiol groups associated to chromatin

Cosmology with the submillimetre galaxies magnification bias: Proof of concept

Context. As recently demonstrated, high-z submillimetre galaxies (SMGs) are the perfect background sample for tracing the mass density profiles of galaxies and clusters (baryonic and dark matter) and their time-evolution through gravitational lensing. Their magnification bias, a weak gravitational lensing eect, is a powerful tool for constraining the free parameters of a halo occupation distribution (HOD) model and potentially also some of the main cosmological parameters. Aims. The aim of this work is to test the capability of the magnification bias produced on high-z SMGs as a cosmological probe. We exploit cross-correlation data to constrain not only astrophysical parameters (Mmin, M1, and ), but also some of the cosmological ones (m, 8, and H0) for this proof of concept. Methods. The measured cross-correlation function between a foreground sample of GAMA galaxies with spectroscopic redshifts in the range 0.2 < z < 0.8 and a background sample of H-ATLAS galaxies with photometric redshifts >1.2 is modelled using the traditional halo model description that depends on HOD and cosmological parameters. These parameters are then estimated by performing a Markov chain Monte Carlo analysis using dierent sets of priors to test the robustness of the results and to study the performance of this novel observable with the current set of data. Results. With our current results, m and H0 cannot be well constrained. However, we can set a lower limit of >0.24 at 95% confidence level (CL) on m and we see a slight trend towards H0 > 70 values. For our constraints on 8 we obtain only a tentative peak around 0.75, but an interesting upper limit of 8 . 1 at 95% CL.We also study the possibility to derive better constraints by imposing more restrictive priors on the astrophysical parameters

Cosmology with the submillimetre galaxies magnification bias: Tomographic analysis

Context. High-z submillimetre galaxies can be used as a background sample for gravitational lensing studies thanks to their magnification bias. In particular, the magnification bias can be exploited in order to constrain the free parameters of a halo occupation distribution (HOD) model and some of the main cosmological parameters. A pseudo-tomographic analysis shows that the tomographic approach should improve the parameter estimation. Aims. In this work the magnification bias has been evaluated as cosmological tool in a tomographic set-up. The cross-correlation function (CCF) data have been used to jointly constrain the astrophysical parameters Mmin, M1, and α in each of the selected redshift bins as well as the cosmological parameters ωM, σ8, and H0 for the lambda cold dark matter (ΛCDM) model. Moreover, we explore the possible time evolution of the dark energy density by also introducing the ω0, ωa parameters in the joint analysis (ω0CDM and ω0ωaCDM). Methods. The CCF was measured between a foreground spectroscopic sample of Galaxy And Mass Assembly galaxies and a background sample of Herschel Astrophysical Terahertz Large Area Survey (H-ATLAS) galaxies. The foreground sample was divided into four redshift bins (0.1-0.2, 0.2-0.3, 0.3-0.5, and 0.5-0.8) and the sample of H-ATLAS galaxies has photometric redshifts > 1.2. The CCF was modelled using a halo model description that depends on HOD and cosmological parameters. Then a Markov chain Monte Carlo method was used to estimate the parameters for different cases. Results. For the ΛCDM model the analysis yields a maximum posterior value at 0.26 with [0.17, 0.41] 68% C.I. for ωM and at 0.87 with [0.75, 1] 68% C.I. for σ8. With our current results H0 is not yet constrained. With a more general ω0CDM model, the constraints on ωM and σ8 are similar, but we found a maximum posterior value for ω0 at -1 with [ - 1.56, -0.47] 68% C.I. In the ω0ωaCDM model, the results are -1.09 with [ - 1.72, -0.66] 68% C.I. for ω0 and -0.19 with [ - 1.88, 1.48] 68% C.I. for ωa. Conclusions. The results on Mmin show a trend towards higher values at higher redshift confirming recent findings. The tomographic analysis presented in this work improves the constraints in the σ8 - ωM plane with respect to previous findings exploiting the magnification bias and it confirms that magnification bias results do not show the degeneracy found with cosmic shear measurements. Moreover, related to dark energy, we found a trend of higher ω0 values for lower H0 values

Track running shoes: a case report of the transition from classical spikes to "super spikes" in track running

Research on high-tech running shoes is increasing but few studies are available about the use of high-tech track spike shoes (super spikes), despite their growing popularity among running athletes. The aim of this case study was to investigate kinematics, kinetics, and plantar pressures of an Olympic running athlete using two different types of shoes, to provide an easy and replicable method to assess their influence on running biomechanics. The tested athlete performed six running trials, at the same speed, wearing a pair of normal spikes shoes (NSS) and a super spikes shoe (SSS), in random order. SSS increased contact time, vertical impact, and swing force (Effect Size 3.70, 7.86, and 1.31, respectively), while it reduced foot-strike type and vertical ground reaction force rate (Effect Size 3.62 and 7.21, respectively). Moreover, a significant change was observed in medial and lateral load, with SSS inducing a more symmetrical load distribution between the left and right feet compared to the NSS (SSS left medial load 57.1 +/- 2.1%, left lateral load 42.9 +/- 1.4%, right medial load 55.1 +/- 2.6%, right lateral load 44.9 +/- 2.6%; NSS left medial load 58.4 +/- 2.6%, left lateral load 41.6 +/- 2.1%, right medial load 49.2 +/- 3.7%, right lateral load 50.8 +/- 3.7%). The results of this case study suggest the importance of using individual evaluation methods to assess shoe adaptations in running athletes, which can induce biomechanical modifications and should be considered by coaches to ensure optimal running performance

Which physical activity in patients affected by hypoparathyroidism? A review of the literature and practical recommendations

Background Hypoparathyroidism (HypoP) is a rare endocrine condition characterized by hypocalcaemia and hyperphos- phatemia, as a consequence of absent or improperly low parathyroid hormone (PTH) levels. Patients affected by HypoP have a clinical condition often characterized by paresthesias and muscle spasms, as well as long-term consequences as nephro- lithiasis, extraskeletal calcification, and fractures. In the literature, likely due to these symptoms, few data exist regarding the appropriate physical activity (PA) in subjects suffering from HypoP. Purpose This review evaluates the literature on exercise-based approaches to the management of individuals affected by HypoP and evaluates: (1) the effects of physical exercise on muscle cramps and other clinical symptoms; (2) the effects of exercise on PTH and calcium level; (3) the most suitable clinical exercise testing; and (4) the most suitable exercise combination. Methods and results A systematic search was conducted using the databases MEDLINE, Google Scholar using “hypopar- athyroidism AND Physical Activity”, “Training AND hypoparathyroidism”, “Exercise AND muscle cramps”, “Exercise AND Fatigue” as keywords. In addition, references list from the included articles were searched and cross-checked to identify any further potentially eligible studies. A total of 50 manuscripts were found among which 39 manuscripts were selected. A few clinical studies have been performed in HypoP patients to evaluate PA training protocols. Conclusion Although further research is needed to draw solid conclusions regarding best PA protocols in subjects affected by HypoP, a PA protocol has been proposed within the manuscript to encourage patients to attempt exercise to improve their clinical conditions and their quality of life

Effect of pre-season training phase on anthropometric, hormonal and fitness parameters in young soccer players

The aims of the study were to investigate 1) the effect of 8 weeks of PSP training on anthropometrics, salivary hormones and fitness parameters in youth soccer players, 2) the correlations between fitness and hormonal parameters, and 3) the impact of the experience of the coach and his methodology of training on these parameters. Weight, height, BMI, pubertal development (PDS), salivary Cortisol (sC), salivary Testosterone (sT), salivary sDHEAS, intermittent tests (VO2max), and countermovement jump test (CMJ) modifications of 35 youth soccer players (age: 14±0 yrs; BMI: 20.8±1.8 k/m2 ) from two Italian clubs (“Lupa Frascati” -LF-; “Albalonga” -AL) were analysed. A significant (p<0.05) time by club effect was observed in sC (F(1,31) = 9.7, ES = 1.13), sT (F(1,31) = 4.2, ES = 0.74), CMJ (F(1,28) = 26.5, ES = 1.94), and VO2max (F(1,28) = 8.5, ES = 1.10). Statistical differences (p<0.05) in weight (F(1,32) = 25.5, ES = 0.11), sC (F(1,31) = 32.1, ES = 1.43), sT/sC ratio (F(1,31) = 10.1, ES = 0.97), sDHEAS/sC ratio (F(1,31) = 6.3, ES = 0.70), and VO2max (F(1,28) = 64.3, ES = 1.74) were found within time factor. Between clubs, differences (p<0.05) in sC (F(1,32) = 8.5, ES = 1.17), sT (F(1,31) = 4.2, ES = 0.74), CMJ (F(1,28) = 26.5, ES = 1.50), and VO2max (F(1,28) = 8.5, ES = 1.10) were found. CMJ was inversely correlated with sDHEAS (r = -0.38) before PSP, while Δ of CMJ showed significant correlations with Δ of sC (r = 0.43) and ΔVO2max was inversely correlated with ΔBMI (r = -0.54) and ΔsC (r = -0.37) in all subjects. Considering each single club, ΔVO2max showed correlations with ΔBMI (r = -0.45) in AL, while ΔCMJ showed correlations with ΔPDS (r = 0.72) in LF club. Since the PSP is often limited training time to simultaneously develop physical, technical and tactical qualities, an efficient method to distribute the training load is important in youth soccer players to increase the performance and to avoid injuries