Air pollution particulate matter exposure and chronic cerebral hypoperfusion and measures of white matter injury in a murine model

BACKGROUND: Exposure to ambient air pollution particulate matter (PM) is associated with increased risk of dementia and accelerated cognitive loss. Vascular contributions to cognitive impairment are well recognized. Chronic cerebral hypoperfusion (CCH) promotes neuroinflammation and blood-brain barrier weakening, which may augment neurotoxic effects of PM. OBJECTIVES: This study examined interactions of nanoscale particulate matter (nPM; fine particulate matter with aerodynamic diameter METHODS: nPM was collected using a particle sampler near a Los Angeles, California, freeway. Mice were exposed to 10 wk of reaerosolized nPM or filtered air (FA) for 150 h. CCH was induced by BCAS surgery. Mice (C57BL/6J males) were randomized to four exposure paradigms: RESULTS: The joint DISCUSSION: Our data suggest that nPM and CCH contribute to white matter injury in a synergistic manner in a mouse model. Adverse neurological effects may be aggravated in a susceptible population exposed to air pollution. https://doi.org/10.1289/EHP8792

Using cross-sectoral collaboration to create long-lasting solutions: How Implementation of the Cascade and Olympic Agendas Seeks to Cross the Urban-Rural Divide

Since the launch of the Cascade and Olympic Agendas in 2005, Forterra (formerly Cascade Land Conservancy) has been working to cross the urban-rural divide to generate equitable, market-based strategies for Creating Great Communities & Conserving Great Lands. Based on the premise that the NW\u27s greatest opportunities for sustainability requires identification of synergies and constituencies across diverse sectors, Forterra has focused on a number of policy and project initiatives to test and prove up this premise. Examples include: the well-advanced Landscape Conservation and Local Infrastructure Program and an emerging collaboration to generate manufacturing of and building code authorizations for locally-sourced engineered and mass timber for use in multi-story buildings. Both of these examples align urban and rural market forces to create compact, carbon-reducing development, while sustaining resource economies, rural communities and the landscape - all of which are critical to the survival of the Salish Se

Norfolk Flood Risk Management Study

PDF of powerpoint presentation given at the workshop The Economic Impacts of Sea-Level Rise in Hampton Roads: An Appraisal of the Projects Underway on May 18, 2016 at the Virginia Modeling and Simulation Center, 1030 University Blvd, Suffolk, VA 2343

Equity for All: Providing Accessible Healthcare for Patients Living with Disabilities

At the end of this activity, students will be able to: Identify relevant resources to assist patients living with disabilities Recommend appropriate patient-specific resources to minimize barriers to health Identify strategies to enhance the healthcare experience of patients living with disabilities Describe the policies that currently exist to enhance care for patients living with disabilitieshttps://digitalcommons.chapman.edu/pharmacy_books/1027/thumbnail.jp

Effects of Low-Level Additions of Salt on Decomposition Rates and Plant Sodium Concentrations in a Southeastern, US Riparian System

Connor Gruntz is an undergraduate student in the School of Biological Sciences at Louisiana Tech University. Sally Entrekin is a faculty member in the Biology Department at the University of Central Arkansas. Michelle Evans-White is a Professor in the Department of Biological Sciences at the University of Arkansas. Natalie Clay is an Assistant Professor in the School of Biological Sciences at Louisiana Tech Universit

Effects of Low-Level Salt Additions on Plant Growth and Implications for Riparian Detrital Processing

The abstract for this presentation can be downloaded by clicking on the blue download button

Here\u27s the Dirt: The Newest Recommendations for Garlic Mustard Management

Garlic mustard (Alliaria petiolata) is an invasive plant that has quickly become naturalized throughout most of the United States. Due in part to high reproductive output and the release of chemical compounds that disturb beneficial plant-fungal associations, this species is able to outcompete many native plants. Over the years, different garlic mustard management strategies been prescribed and implemented with varying success. Here we summarize methods for the removal of garlic mustard based on the most recent literature and research conducted in our lab. We aim to provide a series of clear tasks that landowners, stakeholders, and managers may find useful regarding the eradication of garlic mustard

Preliminary analysis of an instructional alternative to exclusionary discipline

37 pagesDecades of research have shown that exclusionary discipline practices are not only ineffective for changing student behavior, they lead to worse social, behavioral, and academic outcomes for students. This article explores the findings from a pilot study of the Inclusive Skill-Building Learning Approach (ISLA), an instructional alternative to exclusionary discipline practices. The purposes of ISLA are to improve student social and behavioral problem-solving, teacher and administrator practices, and student-teacher relationships while also reducing lost instructional time for student excluded from their learning environment. Results from the pilot indicated that implementation of ISLA was associated with reductions in exclusionary discipline practices (Cohen’s h effect sizes ranged from .06 to .18 across schools and outcomes), and a substantial decrease in instructional minutes lost (~ 92%). Educational staff also reported favorable impressions of the intervention. Practical and conceptual implications, limitations of this study, and directions for future research are further discussed.The research reported here was supported by the Fairway Fund, a College of Education Faculty Research Award at the University of Oregon and by the Institute of Education Sciences, U.S. Department of Education, through Grant R305A180006 to the University of Oregon

Nonsuicidal self-injury, suicidal thoughts and suicide attempts among sexual minority youth in Ireland during their emerging adult years.

AIM: This study aimed to examine whether or not sexual minority youth constitute an at-risk group for nonsuicidal self-injury, suicidal ideation or suicide attempts during their emerging adult years. METHODS: Using data from the Challenging Times Study, a population-based study of psychopathology and suicide in Ireland, analyses were conducted to test the associations between sexual minority status and the odds of any lifetime experience of nonsuicidal self-injury, suicidal thoughts or suicide attempts among Irish youth aged 19-24 years. RESULTS: Sexual minority youth had 6.6-fold (95% CI 1.7-24.7) increased risk of nonsuicidal self-injury, a 5.0-fold (95% CI 1.3-18.3) increased risk of suicidal ideation, a 7.7-fold (95% CI 1.8-32.0) increased risk of suicide intent and a 6.8-fold (95% CI 1.6-27.6) increased risk of a suicide attempt during their lifetime compared to their heterosexual peers. CONCLUSIONS: This study shows that emerging adulthood is a period of risk for suicide and nonsuicidal self-injurious behaviour among sexual minority youth