1,027 research outputs found
Mazur's isogeny theorem
Mazur's isogeny theorem states that if is a prime for which there exists
an elliptic curve that admits a rational isogeny of degree
, then . This result is one of
the cornerstones of the theory of elliptic curves and plays a crucial role in
the proof of Fermat's Last Theorem. In this expository paper, we overview
Mazur's proof of this theorem, in which modular curves and Galois
representations feature prominently.Comment: Expository paper, 16 page
A Unique Perfect Power Decagonal Number
Let denote the th -gonal number. We consider the
equation for integers and . All
solutions to this equation are known for and . We
consider the case , that of decagonal numbers. Using a descent argument
and the modular method, we prove that the only decagonal number
expressible as a perfect th power with is .Comment: 5 pages. Some typos correcte
Quadratic Points on Non-Split Cartan Modular Curves
In this paper we study quadratic points on the non-split Cartan modular
curves , for and . Recently, Siksek proved that all
quadratic points on arise as pullbacks of rational points on
. Using similar techniques for , and employing a version of
Chabauty for symmetric powers of curves for , we show that the same holds
for and . As a consequence, we prove that certain
classes of elliptic curves over quadratic fields are modular.Comment: 18 pages. To appear in International Journal of Number Theory. Minor
corrections and rewriting. Slightly improved sieving step and more
computation details include
FrontiĂšres du caquet en forme de chanson
Mémoire numérisé par la Direction des bibliothÚques de l'Université de Montréal
MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease
<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with brain innate immune activation mainly mediated by microglia. These cells are known to be activated in the brain of AD patients and to produce inflammatory cytokines and neurotoxic molecules in response to Amyloid beta (AÎČ). Activation of microglia can also promote AÎČ clearance via Toll-like receptors (TLRs). Myeloid differentiation factor 88 (MyD88) is the adaptor molecule for most of these innate immune receptors, transducing the intracellular signal from TLRs to nucleus.</p> <p>Results</p> <p>Here, we report that more than 50% reduction in MyD88 expression in a mouse model of AD accelerated spatial learning and memory deficits. Brain of APP<sub>swe</sub>/PS1-MyD88<sup>+/- </sup>mice was characterized by a delay in accumulation of AÎČ plaques and increased soluble levels of AÎČ oligomers. Furthermore, inflammatory monocyte subset and brain IL-1ÎČ gene expression were significantly reduced in APP<sub>swe</sub>/PS1 mice with impaired MyD88 signaling.</p> <p>Conclusions</p> <p>These data indicate that activation of MyD88 intracellular signaling pathway, likely by TLRs, acts as a natural innate immune mechanism to restrict disease progression of APP<sub>swe</sub>/PS1 mice.</p
La comédie de destruction
Celui qui rit du comique sâempĂȘche dâen comprendre la vĂ©ritable nature, remarquait Aby Warburg lorsquâil Ă©voquait, dans sa confĂ©rence sur le rituel du serpent, lâirruption des clowns au milieu des danseurs katchinas Ă laquelle il avait assistĂ© lors de son sĂ©jour en territoire Hopi durant lâhiver 1896. Parce quâil reste confinĂ© dans le registre de la culture populaire, le burlesque cinĂ©matographique des premiers temps Ă©chappe encore aux conventions sentimentales et morales qui viendront en Ă©dulcorer la force au cours des annĂ©es 1920. Brutal, violent, improvisĂ©, il recueille les principes dâune poĂ©tique nĂ©gative animĂ©e par une dynamique de destruction qui affecte Ă la fois les figures et les Ă©lĂ©ments de la composition. La comĂ©die nâest pas lâautre de la tragĂ©die : elle en rĂ©vĂšle le sens. Ă la maniĂšre du satyre nietzschĂ©en sâavançant sur la scĂšne tragique, lâacteur comique rĂ©vĂšle au spectateur, dans un Ă©clat de rire, la profondeur de « lâeffroyable nuit » et la nullitĂ© du principe dâindividuation.The one who laughs at the comical prevents them from understanding its true nature, as Aby Warburg noted when he mentioned, in his lecture on the serpent ritual, the arrival of clowns in the midst of the Kachina dancers that he saw during his sojourn in Hopi territory during the winter of 1896. Since it remained restricted to the field of popular culture, early farcical films escaped the sentimental and moral conventions that would dilute their strength during the 1920s. Brutal, violent, and improvised, they embraced the principles of a negative poetics animated by a dynamic of destruction that affected both the characters and the compositionâs elements. Comedy is not the inverse of tragedy: it reveals its meaning. Like the Nietzschean satyr entering the tragic scene, the comic actor reveals to the spectator, in a burst of laughter, the depth of âthe terrible nightâ and the foolishness of the principle of individuation.Wer ĂŒber das Komische lacht, wird dessen eigentliches Wesen nicht begreifen können, stellte Aby Warburg fest, als er in seinem Vortrag ĂŒber das Schlangenritual das Auftauchen der Clowns inmitten der Katsina-TĂ€nzer kommentierte, deren Ritual er wĂ€hrend seines Aufenthalts im Hopi-Reservat im Winter 1896 miterlebt hatte. Da es sich lediglich in den eng gesteckten Grenzen der PopulĂ€rkultur bewegte, entkam das burleske Kino der ersten Zeit noch den emotionalen und moralischen Konventionen, die seine ursprĂŒngliche Kraft in den 1920er Jahren einfĂ€rbten. Brutal, gewalttĂ€tig, improvisiert, es enthĂ€lt alle Prinzipien einer negativen Poetik, die von der Dynamik der Destruktion angetrieben wird und sich auf Figuren und Elemente der Komposition auswirkt. Die Komödie ist nicht das GegenstĂŒck zur Tragödie: sie legt ihren Sinn frei. So wie Nietzsches Satyr sich in die tragische Szene wagt, so zeigt der Komödiant dem Zuschauer in einem Lachen die Tiefe der âfurchtbaren Nachtâ und die Nichtigkeit des Individuationsprinzips.Colui che ride del comico non riesce a comprenderne la vera natura, notava Aby Warburg quando evocava, nella sua conferenza sul rituale del serpente, lâirruzione dei clowns tra i danzatori katchinas alla quale aveva assistito durante un suo soggiorno in territorio Hopi durante lâinverno 1896. PoichĂ© resta confinato nellâambito della cultura popolare, il burlesco cinematografico dei primi tempi sfugge ancora alle convenzioni sentimentali e morali che vorranno edulcorarne la forza nel corso degli anni Venti. Brutale, violento, improvvisato, esso raccoglie i principi di una poetica negativa animata da una dinamica di distruzione che intacca, allo stesso tempo, le figure e gli elementi della composizione. La commedia non Ăš lâaltro lato della tragedia: essa ne rivela invece il senso. Alla maniera del satiro nietzschiano che avanza sulla scena tragica, lâattore comico rivela allo spettatore, in uno scoppio di risa, la profonditĂ della spaventosa notte e la nullitĂ di un principio di individuazione.Aquel que rĂe de lo cĂłmico se imposibilita comprender su verdadera naturaleza, remarcaba Aby Warburg cuando evocaba, en su conferencia sobre el ritual de la serpiente, la irrupciĂłn de los payasos en medio de los bailarines katchinas a la cual Ă©l habĂa asistido durante su paso por el territorio Hopi en el invierno de 1896. Confinado al registro de la cultura popular, el burlesco cinematogrĂĄfico iniciĂĄtico escapa todavĂa a las convenciones sentimentales y morales que vendrĂĄn a edulcorar su fuerza a partir de 1920. Brutal, violento, improvisado, recoge los principios de una poĂ©tica negativa animada por una dinĂĄmica de la destrucciĂłn que afecta a la vez a las figuras y a los elementos de la composiciĂłn. La comedia no es lo otro de la tragedia: ella revela su sentido. A la manera de un sĂĄtiro nietzscheano avanzando sobre la escena trĂĄgica, el actor cĂłmico revela al espectador, en un estallido de risa, la profundidad del âhorror de la nocheâ y la estupidez del principio de individuaciĂłn
Bill Readings : penser le dissensus dans les âruinesâ de lâuniversitĂ©
Ce mĂ©moire prĂ©sente une interprĂ©tation et une explication critique des propositions principales de lâouvrage posthume de Bill Readings, The University in Ruins (Harvard, 1996). Lâauteur vise Ă introduire la pensĂ©e de Readings en tant que translation du diffĂ©rend lyotardien vers les dĂ©bats autour de la crise des curricula et des « guerres culturelles » amĂ©ricaines. DeuxiĂšmement, ce travail mobilise le dialogue qui lâa opposĂ© au projet pĂ©dagogique de Gerald Graff, lequel trouvait dans la notion de « Conflit » elle-mĂȘme le ciment dâune nouvelle communautĂ© universitaire. La communautĂ© du « dissensus » chez Readings apparaĂźt en comparaison dans toute sa radicalitĂ©. En renonçant Ă lâidĂ©ologie de lâĂ©mancipation du sujet caractĂ©ristique de la modernitĂ©, Readings envisageait la scĂšne de lâenseignement depuis un mode Ă©thique hĂ©tĂ©ronome, et caractĂ©risait la pĂ©dagogie comme relation asymĂ©trique et infinie Ă autrui. Enfin, il sâagit dâexposer comment la communautĂ© du dissensus prĂ©serve comme aporie la question de lâidentitĂ© collective autant que celle de la nature du lien social dans lâuniversitĂ© « dĂ©rĂ©fĂ©rentialisĂ©e ». Pour ce faire, ce mĂ©moire propose sur ces idĂ©es un Ă©clairage nouveau en les rapprochant de la pensĂ©e dialogique et anthropologique bakhtiniennes.This masterâs thesis offers a critical interpretation and exploration of the main proposals of Bill Readingsâ posthumous book, The University in Ruins (Harvard, 1996). I situate Readingsâ provocative thoughts as a translation of Lyotardâs notion of differend into American pedagogical debates within the literary crisis upon the curricula and the so-called âCulture Warsâ. The study expands on the dialogue which opposed Readings to Graff, where the latter sought to posit the notion of âConflictâ as the locus of a renewed academic community. In contrast to Graff, the radicalism of Readingsâ âcommunity of dissensusâ becomes more salient. While renouncing the emancipatory ideals of Modernity, Readings suggested an understanding of education as a space of heteronomous ethics, and pedagogy as an infinite and asymmetrical relationship to others. Finally, I show that the âcommunity of dissensusâ maintains as a permanent question the aporetic nature of its identity as well as of the nature of the social bond within the âpost-historicalâ university. By doing so, this work provides an original contribution which underlines a kinship between Readingsâ most controversial statements and Mikhail Bakhtinâs dialogism and anthropological ideas
Pourvoyeur dâirrĂ©alitĂ©, Fantasmagorie, Ămile Cohl, 1908
Dans le cinĂ©ma des premiers temps se fait jour, de façon fugitive, une conception ornementale de lâimage en mouvement que le cinĂ©ma narratif, fondĂ© sur les ressorts de lâillusionnisme photographique, devait Ă©clipser et dont Fantasmagorie, le premier film de Cohl rĂ©alisĂ© en 1908, pourrait ĂȘtre lâarchĂ©type.In early cinema there appears, fleetingly, an ornamental conception of the moving image, which narrative cinema would soon eclipse and whose archetype might be Fantasmagorie, Cohlâs first film, made in 1908
Fermat's last theorem and modular curves over real quadratic fields
We study the Fermat equation xn+yn=zn over quadratic fields Q(dâ) for squarefree d with 26â€dâ€97. By studying quadratic points on the modular curves X0(N), d-regular primes, and working with Hecke operators on spaces of Hilbert newforms, we extend work of Freitas and Siksek to show that for most squarefree d in this range there are no non-trivial solutions to this equation for nâ„4
Brancusi filma
Abordando a inĂ©dita produção de filmes e as fotografias de Brancusi, o autor destaca como tais meios eram usados pelo artista como instrumentos de reflexĂŁo, que dialogavam com sua produção de esculturas. Na anĂĄlise, coloca-se o ateliĂȘ do artista como espaço de trabalho em transformação, substituindo a ideia de apresentação das obras, pela de sua representação. As relaçÔes entre os meios sĂŁo discutidas a partir de trĂȘs processos de transferĂȘncia: a fotografia como filme, o filme como fotografia e o filme como escultura
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