Acute post cardiac injury syndrome occurring immediately after a demanding percutaneous coronary intervention.

Postcardiac injury syndrome (PCIS) occurs as a complication of myocardial infarction (Dressler's syndrome), of cardiac surgery (post-pericardiotomy syndrome), or post-traumatic (either iatrogenic or non-iatrogenic) and involves a pericardial or myocardial injury. There is scarce data regarding occurrence and pathogenesis of PCIS after invasive procedures. Herein, we describe a unique case of acute PCIS with typical clinical, laboratory, echocardiographic findings that occurred one hour after a demanding multi-stenting percutaneous coronary intervention. Possible pathogenetic mechanisms and treatment options are being discussed

Expedition 381 Summary

The primary objective of International Ocean Discovery Program Expedition 381 was to retrieve a record of early continental rifting and basin evolution from the Corinth rift, central Greece. Continental rifting is fundamental for the formation of ocean basins, and active rift zones are dynamic regions of high geohazard potential. However, the detailed spatial and temporal evolution of a complete rift system needed to understand rift development from the fault to plate scale is poorly resolved. In the active Corinth rift, deformation rates are high, the recent synrift succession is preserved and complete offshore, and earlier rift phases are preserved onshore. Additionally, a dense seismic database provides high-resolution imaging of the fault network and seismic stratigraphy around the basin. As the basin has subsided, its depositional environment has been affected by fluctuating global sea level and its absolute position relative to sea level, and the basin sediments record this changing environment through time. In Corinth, we can therefore achieve an unprecedented precision of timing and spatial complexity of rift-fault system development, rift-controlled drainage system evolution, and basin fill in the first few million years of rift history. The following are the expedition themes: High-resolution fault slip and rift evolution history, Surface processes in active rifts, High-resolution late Quaternary Eastern Mediterranean paleoclimate and paleoenvironment of a developing rift basin, and Geohazard assessment in an active rift. These objectives were and will be accomplished as a result of successful drilling, coring, and logging at three sites in the Gulf of Corinth, which collectively yielded 1645 m of recovered core over a 1905 m cored interval. Together, these cores provide (1) a long rift history (Sites M0078 and M0080), (2) a high-resolution record of the most recent phase of rifting (Site M0079), and (3) the spatial variation of rift evolution (comparison of sites in the central and eastern rift). The sediments contain a rich and complex record of changing sedimentation, sediment and pore water geochemistry, and environmental conditions from micropaleontological assemblages. The preliminary chronology developed by shipboard analyses will be refined and improved during postexpedition research, providing a high-resolution chronostratigraphy down to the orbital timescale for a range of tectonic, sedimentological, and paleoenvironmental studies. This chronology will provide absolute timing of key rift events, rates of fault movement, rift extension and subsidence, and the spatial variations of these parameters. The core data will also allow us to investigate the relative roles of and feedbacks between tectonics, climate, and eustasy in sediment flux, basin evolution, and basin environment. Finally, the Corinth rift boreholes will provide the first long Quaternary record of Mediterranean-type climate in the region. The potential range of scientific applications for this unique data set is very large, encompassing tectonics, sedimentary processes, paleoenvironment, paleoclimate, paleoecology, geochemistry, and geohazards

The holistic perspective of the INCISIVE project : artificial intelligence in screening mammography

Finding new ways to cost-effectively facilitate population screening and improve cancer diagnoses at an early stage supported by data-driven AI models provides unprecedented opportunities to reduce cancer related mortality. This work presents the INCISIVE project initiative towards enhancing AI solutions for health imaging by unifying, harmonizing, and securely sharing scattered cancer-related data to ensure large datasets which are critically needed to develop and evaluate trustworthy AI models. The adopted solutions of the INCISIVE project have been outlined in terms of data collection, harmonization, data sharing, and federated data storage in compliance with legal, ethical, and FAIR principles. Experiences and examples feature breast cancer data integration and mammography collection, indicating the current progress, challenges, and future directions

Impact of masking effect on subclinical carotid atherosclerosis in normotensives and untreated masked hypertensive and hypertensive patients

Objectives The masking effect (ME) is present in masked hypertensive patients; however, both normotensive and hypertensive individuals may show a similar phenomenon. Previous studies have shown that ME has been associated with left ventricular hypertrophy and microalbuminuria in treated hypertensive patients. The aim of our study was to evaluate the association between the magnitude of systolic ME and the extent of common carotid artery intima-media thickness (CCA-IMT) development in normotensive individuals and untreated masked hypertensive and hypertensive patients. Participants and methods A total of 1154 individuals underwent 24 h ambulatory blood pressure (BP) monitoring and carotid artery ultrasonographic measurements. The final study population included 360 patients with systolic ME (daytime systolic BP higher than office systolic BP). The participants were divided into three groups according to office and daytime BP values: normotensives, masked hypertensives, and hypertensives. Results Masked hypertensives presented significantly higher systolic ME (-14.6 mmHg) than their normotensive (-8.2 mmHg) and hypertensive (-9.5 mmHg) counterparts. However, systolic ME was associated significantly with CCA-IMT only in the group of masked hypertensives (r = -0.399, P< 0.001). The multivariate linear regression analyses showed significant and independent associations of CCA-IMT with the following factors: age (B= 0.028, 95% confidence interval: 0.001-0.055; P= 0.044) and systolic ME (B = -0.034, 95% confidence interval: -0.066 to -0.003; P= 0.034). A 10 mmHg decrease in systolic ME correlated to an increase of 0.034 mm in the CCA-IMT. Conclusion Systolic ME was associated significantly with CCA-IMT values in masked hypertensives. Both normotensive and hypertensive participants have failed to show similar associations. Copyright (C) 2015 Wolters Kluwer Health, Inc. All rights reserved

Potential Dam Breach Analysis and Flood Wave Risk Assessment Using HEC-RAS and Remote Sensing Data: A Multicriteria Approach

Dam breach has disastrous consequences for the economy and human lives. Floods are one of the most damaging natural phenomena, and some of the most catastrophic flash floods are related to dam collapses. The goal of the present study is to analyse the impact of a possible failure–collapse on a potentially affected area downstream of the existing Bramianos dam on southern Crete Island. HEC-RAS hydraulic analysis software was used to study the dam breach, the flood wave propagation, and estimate the extent of floods. The analysis was performed using two different relief datasets of the same area: a digital elevation model (DEM) taken from very high-resolution orthophoto images (OPH) of the National Cadastre and Mapping Agency SA and a detailed digital surface model (DSM) extracted from aerial images taken by an unmanned aerial vehicle (UAV). Remote sensing data of the Sentinel-2 satellite and OPH were utilised to create the geographic information system (GIS) layers of a thorough land use/cover classification (LULC) for the potentially flooded area, which was used to assess the impact of the flood wave. Different dam breach and flood scenarios, where the water flows over man-made structures, settlements, and olive tree cultivations, were also examined. The study area is dominated mainly by three geological formations with different hydrogeological characteristics that dictated the positioning and structure of the dam and determine the processes that shape the geomorphology and surface roughness of the floodplain, affecting flow conditions. The results show that the impact of a potential dam break at Bramianos dam is serious, and appropriate management measures should be taken to reduce the risk. The water flow downstream of the collapsed dam depends on the water volume stored in the reservoir. Moreover, the comparison of DSM and DEM cases shows that the detailed DSM may indicate more accurately the surface relief and existing natural obstacles such as vegetation, buildings, and greenhouses, enabling more realistic hydraulic simulation results. Dam breach flood simulations and innovative remote sensing data can provide valuable outcomes for engineers and stakeholders for decision-making and planning in order to confront the consequences of similar incidents worldwide