776 research outputs found

    Investigation of BOLD using CARR-PURCELL T2 Weighting with SPIRAL Readout

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    It is demonstrated that a Carr-Purcell (CP) technique based on the fully adiabatic pulse sequence (CP-LASER) with SPIRAL readout can be used to generate zoomed images with relatively short acquisition window (at) for the investigation of the mechanisms of the BOLD effect. Based on the capability of the developed technique to refocus the dynamic dephasing, it is demonstrated that the BOLD effect is suppressed as the pulse interval cp of CP-LASER sequence decreased

    Motion Deblurring in the Wild

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    The task of image deblurring is a very ill-posed problem as both the image and the blur are unknown. Moreover, when pictures are taken in the wild, this task becomes even more challenging due to the blur varying spatially and the occlusions between the object. Due to the complexity of the general image model we propose a novel convolutional network architecture which directly generates the sharp image.This network is built in three stages, and exploits the benefits of pyramid schemes often used in blind deconvolution. One of the main difficulties in training such a network is to design a suitable dataset. While useful data can be obtained by synthetically blurring a collection of images, more realistic data must be collected in the wild. To obtain such data we use a high frame rate video camera and keep one frame as the sharp image and frame average as the corresponding blurred image. We show that this realistic dataset is key in achieving state-of-the-art performance and dealing with occlusions

    Maximizing Tissue Contrast for MRI Evaluation of Parkinson’s Disease

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    A Pilot Program For The Recruitment and Education of Navy Veterans Based on System-Level Technical Expertise and Leadership Maturation Developed During Service

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    The project, Stern2STEM, aims to advance STEM (Science, Technology, Engineering, and Mathematics) education through the preparation of student veterans to pursue baccalaureate STEM degrees and support the re-employment of these veterans into the Department of Defense (DoD) and the wider defense support industry. The program builds on the training that veterans have received in highly skilled technical areas, both in the classroom and “on-the-job”, to develop system level expertise in their respective technical disciplines. Key components of the program include: (1) establishing a mechanism for outreach and recruitment; (2) providing leveling, tutoring, mentoring, and support for students; (3) teaching and learning through proven pedagogical practices and through sound academic advising; (4) partnering with the DoD community to facilitate student career placement in the DoD STEM workforce; (5) providing workforce development for DoD STEM professionals. This paper will discuss the academic challenges that student veterans face while in higher education and the current STEM pipelines as students move through their college to professional careers. The early impact of academic tutoring, professional advising, mentorship, career placement, and recruitment of current service members into STEM disciplines through involvement with Stern2STEM will be discussed. Through Stern2STEM’s systematic interventions, the project has the potential to have a significant impact on the broader STEM education community as many of the principles, lessons learned, and tools developed will prove valuable for institutions which have a large population of student veterans

    Integration Concept of Injection, Forming and Foaming: A Practical Approach to Manufacture Hybrid Structures

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    Motivated by the concept of the integrative production systems, the hybrid process of polymer injection molding and sheet metal forming, known as polymer injection forming (PIF), has been introduced to manufacture sheet metal-polymer components in a single operation. Despite the wide potential application of this technology, its implementation in actual industrial production has been hindered due to several challenges; a thick layer of polymer where there is deep deformation, non-uniform deformation due to pressure loss and the opposite phenomena of shrinkage and springback. To mitigate these practical issues, the novel idea of integrating supercritical fluid (Sc.F.) technology with the PIF process is introduced in this work. As the proposed technology is a manufacturing innovation, with no available information in the literature correlating to this concept, two sets of experiments are designed to investigate the feasibility of this integration. In the first set, the effect of blank material and shot volume as design variables were investigated over a range of Sc.F. weight percentage. To improve the cell morphology in experiments with the low-strength sheet material, several other processing scenarios are explored in the second set of experiments. The results of this study clearly demonstrate the capabilities of this concept manufacturing process in terms of initiating the foaming process within the simultaneous injection/forming process, ensuring weight reduction (of up to 16%) and complete elimination of issues related to shrinkage

    Французский колониализм во Вьетнаме: становление и особенности

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    Актуальность исследовательской работы связана с тем, что французский колониальный период является важным периодом национальной истории Вьетнамцев.Кроме того, эта проблема также является одной из центральных тем исторического дискурса, описывающая мировую политическую стратификацию за предыдущие пять столетий, и, одновременно, имеющая прецеденты в современности. Работа представляет собой комплексный анализ характеристики французского колониализма во Вьетнаме и основных воздействий французского колониализма на развитие современного Вьетнама.The importance of research work relates to the fact that French colonial period is an important period in the national history of Vietnameses. Moreover, this issue is also considered as the central themes of historical discourse, describing the world political stratification in the five previous centuries and, simultaneously with precedents in modern times. The research work is a comprehensive analysis of French colonialism’s characteristics in Vietnam and some major influences of this colonial regime on the development of modern Vietnam

    Proteinaceous microspheres for targeted RNA delivery prepared by an ultrasonic emulsification method

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    In the present work we used sonochemically prepared proteinaceous BSA spheres as a novel RNA-delivery system. The preparation of RNA-loaded BSA spheres was accomplished using an environmental friendly method termed the “ultrasonic emulsification method”. It was demonstrated that ultrasonic waves do not cause the RNA chains to degrade and the RNA molecules remain untouched. The BSA–RNA complex was successfully introduced into mammalian (human) U2OS osteosarcoma cells and Trypanosoma brucei parasites. Using PVA coating of the RNA–BSA spheres we have achieved a significant increase in the number of microspheres penetrating mammalian cells. The mechanism of RNA encapsulation and the structure of the RNA–BSA complex are reported.Ulyana Shimanovich thanks Ministry of Science and Technology, Israel for the "Woman in Science" scholarship (3-8219)

    LAS BATALLAS FESTIVAS DE ESPANA

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    Serving individual customer needs at reasonable prices can be a profitable target market in high-wage countries. The dilemma between scale and scope-oriented production is one major research topic within the Cluster of Excellence "Integrative Production Technology for High-Wage Countries" at the RWTH Aachen University. One main objective of this project is to bridge the existing gap between individual manufacturing and mass production. Modularization is a widely accepted approach in tool-based manufacturing processes. In this paper, we propose a flexible design methodology for modular tools and dies. The methodology will assist the design engineer in setting up a series of modularized tools in a conceptually closed manner. The described methodology covers modularization in a broad sense, i.e. it includes hardware modularization as well as modularization of the construction process. The methodology consists of three phases: initiation, analysis and design phase
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